Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Veronica Colomer"'
Publikováno v:
Biochemical and Biophysical Research Communications. 288:1071-1077
Immature secretory granules (ISG's) are sites of segregation of proteins destined for secretion by unregulated pathways from those stored in mature secretory granules in endocrine cells. To determine whether significant soluble protein sorting occurs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c1f5b8b8468743c56fd538f8163afb7
https://doi.org/10.1006/bbrc.2001.5889
https://doi.org/10.1006/bbrc.2001.5889
Autor:
Christine M. Disteche, Veronica Colomer, K. Duan, C.A. Ross, Sushma S. Thomas, Jamal Nasir, Simone Engelender, Michael R. Hayden, Roxann Ashworth, K. Nichol
Publikováno v:
Mammalian Genome. 9:565-570
Huntington's Disease (HD) is an inherited progressive neurodegenerative disorder associated with a mutation in a gene expressed in both affected and non-affected tissues. The selective neuropathology in HD is thought to be mediated in part through in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf50192dc2a37c85a28f2958f02b46b7
https://doi.org/10.1007/s003359900819
https://doi.org/10.1007/s003359900819
Autor:
Simone Engelender, Christopher A. Ross, Anthony Lanahan, Paul F. Worley, Mariko Tokito, Alan H. Sharp, Veronica Colomer, Erika L.F. Holzbaur
Publikováno v:
Human Molecular Genetics. 6:2205-2212
Huntington's disease (HD) is an inherited neurodegenerative disease caused by expansion of a polyglutamine repeat in the HD protein huntingtin. Huntingtin's localization within the cell includes an association with cytoskeletal elements and vesicles.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e8f96cc7bdd9570c96bc7bc40956755
https://doi.org/10.1093/hmg/6.13.2205
https://doi.org/10.1093/hmg/6.13.2205
Autor:
Mark W. Becher, Veronica Colomer, Simone Engelender, Alan H. Sharp, Christopher A. Ross, Jon D. Wood
Publikováno v:
Brain Pathol
Each of the glutamine repeat neurodegenerative diseases has a particular pattern of pathology largely restricted to the CNS. However, there is considerable overlap among the regions affected, suggesting that the diseases share pathogenic mechanisms,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2c314cdd53e1c1d0f42b4c333014d84
https://doi.org/10.1111/j.1750-3639.1997.tb00898.x
https://doi.org/10.1111/j.1750-3639.1997.tb00898.x
Publikováno v:
Journal of Biological Chemistry. 271:48-55
A major unresolved issue in the field of secretory granule biogenesis is the extent to which the aggregation of granule content proteins is responsible for the sorting of regulated from constitutively secreted proteins. The aggregation process is pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8b465c5de408d7b144be862800eea7d
https://doi.org/10.1074/jbc.271.1.48
https://doi.org/10.1074/jbc.271.1.48
Autor:
Jesse Mez, Scott M. Katzen, Peter R. Mouton, Akira Kakizuka, Noam Kurtis, Lea Ben-Haïem, Veronica Colomer, Neal G. Copeland, Christopher A. Ross, Jennifer Kiluk, Nancy A. Jenkins, Alan H. Sharp, Daniel Goti
Machado-Joseph disease (MJD) is an inherited neurodegenerative disorder caused by ataxin-3 with a polyglutamine expansion. It is proposed that a toxic cleavage fragment of mutant ataxin-3 alternatively spliced isoform mjd1a triggers neurodegeneration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e4a304f2d2560f3d8d9ea8ac0c1b8d
https://europepmc.org/articles/PMC6730179/
https://europepmc.org/articles/PMC6730179/
Autor:
Russell L. Margolis, R. Ingersoll, Veronica Colomer, Simone Engelender, K. Duan, Michael R. Hayden, M.-J. Lafuente, Jamal Nasir, Christopher A. Ross
Publikováno v:
Gene. 254(1-2)
The huntingtin-associated protein (HAP-1) interacts with the Huntington disease gene product, huntingtin. It is predominantly expressed in the brain and shows an increased affinity for mutant huntingtin. We have sequenced an 18,656 bp genomic region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fde6292967a800c2cac607800067cdd
https://pubmed.ncbi.nlm.nih.gov/10974549
https://pubmed.ncbi.nlm.nih.gov/10974549
Autor:
Alan H. Sharp, John J. Kleiderlein, Jonathan Kushi, K. Duan, Christopher A. Ross, Joseph P. Yuan, Russell L. Margolis, Veronica Colomer, Zachary Kaminsky, Jonathan D. Wood
Publikováno v:
Molecular and cellular neurosciences. 11(3)
Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy (DRPLA). The normal function of atrophin-1 is unknown. We have identified five atrophin-1 interacting proteins (AIPs) which bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1dc7beac28f64e1b4ec1c46e8b7299b
https://pubmed.ncbi.nlm.nih.gov/9647693
https://pubmed.ncbi.nlm.nih.gov/9647693
Autor:
Chiara Zurzolo, Rosalia Mora, Enrique Rodriguez-Boulan, Concetta Lipardi, Lucio Nitsch, Veronica Colomer, Simona Paladino
Publikováno v:
The Journal of Cell Biology
Most epithelial cells sort glycosylphosphatidylinositol (GPI)-anchored proteins to the apical surface. The “raft” hypothesis, based on data mainly obtained in the prototype cell line MDCK, postulates that apical sorting depends on the incorporati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d9c8f6296afd43af9e4a3570c4330d3
http://hdl.handle.net/11588/346022
http://hdl.handle.net/11588/346022
Autor:
Veronica Colomer-Gould, Vincenzo Enea
Publikováno v:
Molecular and biochemical parasitology. 43(1)
The circumsporozoite (CS) gene encodes the most immunogenic component of the plasmodial sporozoites. The immunodominant epitope-encoding domain of the CS gene shows sequences that are repeated in tandem. A detailed analysis of the CS repeats of certa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5e5b1de927140a3b77598f5fd0718fd
https://pubmed.ncbi.nlm.nih.gov/2290446
https://pubmed.ncbi.nlm.nih.gov/2290446