Výsledky vyhledávání - "Veronica Clemens"

Immune responses elicited by the GEN-003 candidate HSV-2 therapeutic vaccine in a randomized controlled dose-ranging phase 1/2a trial

Autor: Lena Kien, Veronica Clemens, Seth Hetherington, Jessica Flechtner, Matthew Brudner, Amy Baccari, Deborah Long, Shane Larson, Mojca Skoberne, Jason Chan

Publikováno v: Vaccine. 34:5314-5320

Purpose GEN-003 is a candidate therapeutic HSV-2 vaccine containing a fragment of infected cell protein 4 (ICP4.2), a deletion mutant of glycoprotein D2 (gD2ΔTMR), and Matrix-M2 adjuvant. In a dose-ranging phase 1/2a clinical trial, immunization wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b304463037fc832358f2ad5eaba0ea84
https://doi.org/10.1016/j.vaccine.2016.09.001

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Functional Antibody Responses to GEN-003, a Herpes Simplex Virus Immunotherapy that Durably Reduces Viral Shedding up to 12 Months Post Dosing

Autor: Thomas Oliphant, Jessica Flechtner, Amy Baccari, Johanna K. Kaufmann, Seth Hetherington, Bin Zhang, Nicolle Siddall, Lisa K. McNeil, Shane Larson, Veronica Clemens

Publikováno v: Open Forum Infectious Diseases. 3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0d8466447d3d48b51c41e8e9caaa6b55
https://doi.org/10.1093/ofid/ofw172.1046

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Significant Neutralizing Antibody and Cytolytic T Cell Responses to GEN-003, a Herpes Simplex Virus Immunotherapy, in a Phase 2b Study

Autor: Thomas Oliphant, Amy Baccari, Nicolle Siddall, David Dominguez, Lisa K. McNeil, Tyler Fenske, Veronica Clemens, James Perry, Jessica Flechtner, Seth Hetherington, Thomas C. Heineman, Jin Yuan

Publikováno v: Open Forum Infectious Diseases. 4:S519-S519

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6ca52b8120e69cb838ce894f5e8e1042
https://doi.org/10.1093/ofid/ofx163.1351

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Identification of novel virus-specific antigens by CD4⁺ and CD8⁺ T cells from asymptomatic HSV-2 seropositive and seronegative donors

Autor: Danielle Garvie, Veronica Clemens, Deborah Long, Jessica Price, Shane Larson, Todd Gierahn, Mojca Skoberne, George R. Siber, Jessica Flechtner, Kenya Prince Cohane, Amy Baccari

Publikováno v: Virology.

Reactivation of latent herpes simplex virus 2 (HSV-2) infections can be characterized by episodic recurrent genital lesions and/or viral shedding. We hypothesize that infected (HSV-2(pos)) asymptomatic individuals have acquired T cell responses to sp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfccc013e8f4e6ec8742ff74563a118c
https://pubmed.ncbi.nlm.nih.gov/25108380

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