Výsledky vyhledávání - "Veronica Ayechu Muruzabal"

Akademický článek

Specific Human Milk Oligosaccharides Differentially Promote Th1 and Regulatory Responses in a CpG-Activated Epithelial/Immune Cell Coculture

Autor: Marit Zuurveld, Veronica Ayechu-Muruzabal, Gert Folkerts, Johan Garssen, Belinda van‘t Land, Linette E. M. Willemsen

Publikováno v: Biomolecules, Vol 13, Iss 2, p 263 (2023)

Proper early life immune development creates a basis for a healthy and resilient immune system, which balances immune tolerance and activation. Deviations in neonatal immune maturation can have life-long effects, such as development of allergic disea

Externí odkaz: https://doaj.org/article/174543ab9a78449bbf825591f5d3654f

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Akademický článek

Human Milk Oligosaccharide 2′-Fucosyllactose Modulates Local Viral Immune Defense by Supporting the Regulatory Functions of Intestinal Epithelial and Immune Cells

Autor: Veronica Ayechu-Muruzabal, Bente Poelmann, Alinda J. Berends, Nienke Kettelarij, Johan Garssen, Belinda van’t Land, Linette E. M. Willemsen

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 18, p 10958 (2022)

Human milk contains bioactive components that provide protection against viral infections in early life. In particular, intestinal epithelial cells (IEC) have key regulatory roles in the prevention of enteric viral infections. Here we established an

Externí odkaz: https://doaj.org/article/a262bcb1f475472a9eb4a64ba3008b59

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Akademický článek

Modulation of the Epithelial-Immune Cell Crosstalk and Related Galectin Secretion by DP3-5 Galacto-Oligosaccharides and β-3′Galactosyllactose

Autor: Veronica Ayechu-Muruzabal, Melanie van de Kaa, Reshmi Mukherjee, Johan Garssen, Bernd Stahl, Roland J. Pieters, Belinda van’t Land, Aletta D. Kraneveld, Linette E. M. Willemsen

Publikováno v: Biomolecules, Vol 12, Iss 3, p 384 (2022)

Prebiotic galacto-oligosaccharides (GOS) were shown to support mucosal immune development by enhancing regulatory-type Th1 immune polarization induced by synthetic CpG oligodeoxynucleotides (TLR9 agonist mimicking a bacterial DNA trigger). Epithelial

Externí odkaz: https://doaj.org/article/bcf952359cc64444bc79cc8576a8b9a6

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Akademický článek

A Fermented Milk Matrix Containing Postbiotics Supports Th1- and Th17-Type Immunity In Vitro and Modulates the Influenza-Specific Vaccination Response In Vivo in Association with Altered Serum Galectin Ratios

Autor: Veronica Ayechu-Muruzabal, Ling Xiao, Tjalling Wehkamp, Ingrid van Ark, Elisabeth J. Hoogendoorn, Thea Leusink-Muis, Gert Folkerts, Johan Garssen, Linette E. M. Willemsen, Belinda van’t Land

Publikováno v: Vaccines, Vol 9, Iss 3, p 254 (2021)

During a specific milk fermentation process with Bifidobacterium breve C50 and Streptococcus thermophilus 065 (LactofidusTM), postbiotics with possible immunomodulatory properties are produced. We investigated the effects of this fermentation product

Externí odkaz: https://doaj.org/article/3c11a1001d9245208010ba28dd97384d

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Akademický článek

Exposure of Intestinal Epithelial Cells to 2′-Fucosyllactose and CpG Enhances Galectin Release and Instructs Dendritic Cells to Drive Th1 and Regulatory-Type Immune Development

Autor: Veronica Ayechu-Muruzabal, Saskia A. Overbeek, Atanaska I. Kostadinova, Bernd Stahl, Johan Garssen, Belinda van’t Land, Linette E.M. Willemsen

Publikováno v: Biomolecules, Vol 10, Iss 5, p 784 (2020)

Intestinal epithelial cells (IEC) release immunomodulatory galectins upon exposure to CpG DNA (mimicking bacterial triggers) and short-chain galacto- and long-chain fructo-oligosaccharides (GF). This study aims to investigate the immunomodulatory pro

Externí odkaz: https://doaj.org/article/3f76737ef0e646cebb5786112cdc6d2d

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Akademický článek

Diversity of Human Milk Oligosaccharides and Effects on Early Life Immune Development

Autor: Veronica Ayechu-Muruzabal, Arthur H. van Stigt, Marko Mank, Linette E. M. Willemsen, Bernd Stahl, Johan Garssen, Belinda van't Land

Publikováno v: Frontiers in Pediatrics, Vol 6 (2018)

One of the well-known features of human milk, is the capacity to protect against the risk and impact of neonatal infections, as well as to influence the onset of allergic and metabolic disease manifestations. The major objective of this review is to

Externí odkaz: https://doaj.org/article/e4b7a7275d6d4cd29ea4f0cd049a7cd8

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Akademický článek

Raw Cow’s Milk Reduces Allergic Symptoms in a Murine Model for Food Allergy—A Potential Role for Epigenetic Modifications

Autor: Suzanne Abbring, Johanna Wolf, Veronica Ayechu-Muruzabal, Mara A.P. Diks, Bilal Alashkar Alhamwe, Fahd Alhamdan, Hani Harb, Harald Renz, Holger Garn, Johan Garssen, Daniel P. Potaczek, Betty C.A.M. van Esch

Publikováno v: Nutrients, Vol 11, Iss 8, p 1721 (2019)

Epidemiological studies identified raw cow’s milk consumption as an important environmental exposure that prevents allergic diseases. In the present study, we investigated whether raw cow’s milk has the capacity to induce tolerance to an unrelate

Externí odkaz: https://doaj.org/article/cf2403cb2b104e13837327c53a66e19f

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