Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Veronica Aedo-Lopez"'
Autor:
André Manuel da Silva Lopes, Sara Colomer-Lahiguera, Célia Darnac, Stellio Giacomini, Sébastien Bugeia, Garance Gutknecht, Gilliosa Spurrier-Bernard, Michel Cuendet, Fanny Muet, Veronica Aedo-Lopez, Nuria Mederos, Olivier Michielin, Alfredo Addeo, Sofiya Latifyan, Manuela Eicher
Publikováno v:
JMIR Research Protocols, Vol 12, p e48386 (2023)
BackgroundManagement of severe symptomatic immune-related adverse events (IrAEs) related to immune checkpoint inhibitors (ICIs) can be facilitated by timely detection. As patients face a heterogeneous set of symptoms outside the clinical setting, rem
Externí odkaz:
https://doaj.org/article/7eb558a2a18346f7a7e9ccc15a86392c
Publikováno v:
Frontiers in Surgery, Vol 9 (2022)
IntroductionGender equity in medicine has become a significant topic of discussion due to consistently low female representation in academia and leadership roles. Gender imbalance directly affects patient care. This study examined the gender and craf
Externí odkaz:
https://doaj.org/article/93991fb544a24c2695c80b5b8aa77802
Autor:
Eric Taing Mounnarath, Walid Zwieky, Veronica Aedo-Lopez, Obaidullah Fazli, Berenice Jean Sheridan
Publikováno v:
SAGE Open Medical Case Reports, Vol 10 (2022)
The Wilms tumour is the fourth most common paediatric malignancy. On the contrary, it is extremely rare in adults as it accounts for less than 1% of all renal malignancies. This scarcity of cases placed a significant challenge in generating evidence-
Externí odkaz:
https://doaj.org/article/d141225b41c04456a0b8d02d8ddd7d48
Autor:
Fanny Seraphine Krebs, Bianca Moura, Edoardo Missiaglia, Veronica Aedo-Lopez, Olivier Michielin, Petros Tsantoulis, Bettina Bisig, Mounir Trimech, Vincent Zoete, Krisztian Homicsko
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4520 (2023)
The development of targeted therapies for non-BRAF p.Val600-mutant melanomas remains a challenge. Triple wildtype (TWT) melanomas that lack mutations in BRAF, NRAS, or NF1 form 10% of human melanomas and are heterogeneous in their genomic drivers. MA
Externí odkaz:
https://doaj.org/article/6e05220d67084f598aef1d934deb7008
Autor:
Carole Bandiera, Isabella Locatelli, Perrine Courlet, Evelina Cardoso, Khalil Zaman, Athina Stravodimou, Ana Dolcan, Apostolos Sarivalasis, Jean-Philippe Zurcher, Veronica Aedo-Lopez, Jennifer Dotta-Celio, Solange Peters, Monia Guidi, Anna Dorothea Wagner, Chantal Csajka, Marie P. Schneider
Publikováno v:
Cancers, Vol 15, Iss 1, p 316 (2023)
The cyclin-dependent kinase 4/6 inhibitor (CDK4/6i) palbociclib is administered orally and cyclically, causing medication adherence challenges. We evaluated components of adherence to palbociclib, its relationship with pharmacokinetics (PK), and drug
Externí odkaz:
https://doaj.org/article/e6a9eb86102f48dda445e51a3e7d7df4
Autor:
Vincent Pillonel, Vincent Dunet, Andreas F. Hottinger, Gregoire Berthod, Luis Schiappacasse, Solange Peters, Olivier Michielin, Veronica Aedo-Lopez
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-6 (2019)
Abstract Background Immune checkpoint inhibitors (ICPis) have revolutionised the treatment of melanoma by significantly increasing survival rates and disease control. However, ICPis can have specific immune-related adverse events, including rare but
Externí odkaz:
https://doaj.org/article/a9ca01da9ef54827a9cf91bbd1aeee21
Autor:
Bianca Gautron Moura, Camille L. Gerard, Nathalie Testart, Marian Caikovski, Alexandre Wicky, Veronica Aedo-Lopez, Grégoire Berthod, Krisztian Homicsko, John O. Prior, Clarisse Dromain, Lana E. Kandalaft, Michel A. Cuendet, Olivier Michielin
Publikováno v:
Cancers, Vol 15, Iss 1, p 31 (2022)
Combined ipilimumab and nivolumab significantly improve outcomes in metastatic melanoma patients but bear an important financial impact on the healthcare system. Here, we analyze the treatment costs, focusing on irAE. We conducted a retrospective ana
Externí odkaz:
https://doaj.org/article/3415957103b8466e9532cd8b162a1f62
Autor:
Erika Richtig, Joanna Mangana, Christian Posch, Christoph Hoeller, Julia Maria Ressler, Matthias Karasek, Lukas Koch, Rita Silmbrod, Veronica Aedo-Lopez, Helmut Kehrer, Felix Weihsengruber, Peter Koelblinger, Julian Kofler, Christine Hafner
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 2 (2021)
Background Talimogene laherparepvec (T-VEC) is a licensed therapy for use in melanoma patients of stage IIIB-IVM1a with injectable, unresectable metastatic lesions in Europe. Approval was based on the Oncovex Pivotal Trial in Melanoma study, which al
Externí odkaz:
https://doaj.org/article/ea3dbbcfc7aa40dd9cf2d630e1cec0b6
Autor:
Veronica Aedo-Lopez, Camille L. Gérard, Sarah Boughdad, Bianca Gautron Moura, Gregoire Berthod, Antonia Digklia, Krisztian Homicsko, Niklaus Schaefer, Rafael Duran, Michel A. Cuendet, Olivier Michielin
Publikováno v:
Cancers, Vol 14, Iss 5, p 1162 (2022)
To assess the safety and efficacy of ipilimumab plus nivolumab around selective internal radiation therapy (SIRT) in patients with metastatic uveal melanoma (mUM). We present a retrospective, single center study of 32 patients with mUM divided into t
Externí odkaz:
https://doaj.org/article/54372c4e1c594502b7385c09e20339d6
Autor:
Fanny S. Krebs, Camille Gérard, Alexandre Wicky, Veronica Aedo-Lopez, Edoardo Missiaglia, Bettina Bisig, Mounir Trimech, Olivier Michielin, Krisztian Homicsko, Vincent Zoete
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 8021 (2020)
We report a case of an uveal melanoma patient with GNAQ p.Gly48Leu who responded to MEK inhibition. At the time of the molecular analysis, the pathogenicity of the mutation was unknown. A tridimensional structural analysis showed that Gαq can adopt
Externí odkaz:
https://doaj.org/article/8b601cb30f094e7ea5e5472d01ca60e2