Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Veronica, Ghini"'
Autor:
Veronica Ghini
Publikováno v:
Inorganics, Vol 12, Iss 6, p 168 (2024)
Despite the increasing interest in the development of novel metal-based compounds for cancer treatment, these molecules are currently poorly characterized in mechanistic terms, due to their multiple macromolecular targets inside the cells. In this re
Externí odkaz:
https://doaj.org/article/810a7fa794ce49d4be875fca37138850
Publikováno v:
Cells, Vol 13, Iss 8, p 661 (2024)
Cancer cell lines are frequently used in metabolomics, such as in vitro tumor models. In particular, A2780 cells are commonly used as a model for ovarian cancer to evaluate the effects of drug treatment. Here, we compare the NMR metabolomics profiles
Externí odkaz:
https://doaj.org/article/1c511b77f5d547dc98c592bc1b26a9b0
Autor:
Veronica Ghini, Walter Vieri, Tommaso Celli, Valentina Pecchioli, Nunzia Boccia, Tania Alonso-Vásquez, Lorenzo Pelagatti, Marco Fondi, Claudio Luchinat, Laura Bertini, Vieri Vannucchi, Giancarlo Landini, Paola Turano
Publikováno v:
PLoS Pathogens, Vol 19, Iss 11, p e1011787 (2023)
Plasma of COVID-19 patients contains a strong metabolomic/lipoproteomic signature, revealed by the NMR analysis of a cohort of >500 patients sampled during various waves of COVID-19 infection, corresponding to the spread of different variants, and ha
Externí odkaz:
https://doaj.org/article/3dcc4f1be0ec479088b1bc0e377e0aa3
Autor:
Christopher Riccardi, Marzia Calvanese, Veronica Ghini, Tania Alonso-Vásquez, Elena Perrin, Paola Turano, Giorgio Giurato, Alessandro Weisz, Ermenegilda Parrilli, Maria Luisa Tutino, Marco Fondi
Publikováno v:
mSystems, Vol 8, Iss 2 (2023)
ABSTRACT Microbial communities experience continuous environmental changes, with temperature fluctuations being the most impacting. This is particularly important considering the ongoing global warming but also in the “simpler” context of seasona
Externí odkaz:
https://doaj.org/article/5fc33df373954d3188475e4bfd30419d
Autor:
Veronica Ghini, Gaia Meoni, Lorenzo Pelagatti, Tommaso Celli, Francesca Veneziani, Fabrizia Petrucci, Vieri Vannucchi, Laura Bertini, Claudio Luchinat, Giancarlo Landini, Paola Turano
Publikováno v:
PLoS Pathogens, Vol 18, Iss 4 (2022)
Metabolomics and lipidomics have been used in several studies to define the biochemical alterations induced by COVID-19 in comparison with healthy controls. Those studies highlighted the presence of a strong signature, attributable to both metabolite
Externí odkaz:
https://doaj.org/article/09104308b92c4fbf9ea38cacc82c392c
Autor:
Veronica Ghini, Laura Maggi, Alessio Mazzoni, Michele Spinicci, Lorenzo Zammarchi, Alessandro Bartoloni, Francesco Annunziato, Paola Turano
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
1H NMR spectra of sera have been used to define the changes induced by vaccination with Pfizer-BioNTech vaccine (2 shots, 21 days apart) in 10 COVID-19-recovered subjects and 10 COVID-19-naïve subjects at different time points, starting from before
Externí odkaz:
https://doaj.org/article/45750eecf21141039b27e2162cd804ec
Autor:
Elena Perrin, Veronica Ghini, Michele Giovannini, Francesca Di Patti, Barbara Cardazzo, Lisa Carraro, Camilla Fagorzi, Paola Turano, Renato Fani, Marco Fondi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
It is thought that when multiple carbon sources are available, bacteria metabolize them either sequentially or simultaneously. Here, the authors show that a marine bacterium can use a mixed strategy when multiple possible nutrients are provided, and
Externí odkaz:
https://doaj.org/article/21233beabc35403aa26a55265b2622ac
Autor:
Francesca Cantini, Emanuele Andreano, Ida Paciello, Veronica Ghini, Francesco Berti, Rino Rappuoli, Lucia Banci
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 1981 (2022)
The higher-order structure (HOS) of protein therapeutics has been confirmed as a critical quality parameter. In this study, we compared 2D 1H-13C ALSOFAST-HMQC NMR spectra with immunochemical ELISA-based analysis to evaluate their sensitivity in asse
Externí odkaz:
https://doaj.org/article/226ecd17b12e421781c070bfbaac9012
Autor:
Giuseppina D’Alessandro, Deborah Quaglio, Lucia Monaco, Clotilde Lauro, Francesca Ghirga, Cinzia Ingallina, Michela De Martino, Sergio Fucile, Alessandra Porzia, Maria Amalia Di Castro, Federica Bellato, Francesca Mastrotto, Mattia Mori, Paola Infante, Paola Turano, Stefano Salmaso, Paolo Caliceti, Lucia Di Marcotullio, Bruno Botta, Veronica Ghini, Cristina Limatola
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-12 (2019)
Abstract Background Glioma is the most common and primary brain tumors in adults. Despite the available multimodal therapies, glioma patients appear to have a poor prognosis. The Hedgehog (Hh) signaling is involved in tumorigenesis and emerged as a p
Externí odkaz:
https://doaj.org/article/ff7751943fc1431e869c9fb22d5bcc4c
Autor:
Matteo Becatti, Andrea Bencini, Silvia Nistri, Luca Conti, Maria Giulia Fabbrini, Laura Lucarini, Veronica Ghini, Mirko Severi, Claudia Fiorillo, Claudia Giorgi, Lorenzo Sorace, Barbara Valtancoli, Daniele Bani
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-20 (2019)
Abstract Oxidative stress due to excess superoxide anion ($${{\bf{O}}}_{{\bf{2}}}^{{\boldsymbol{\cdot }}{\boldsymbol{-}}}$$ O2⋅− ) produced by dysfunctional mitochondria is a key pathogenic event of aging and ischemia-reperfusion diseases. Here,
Externí odkaz:
https://doaj.org/article/04182cdca23f47ec9e1ab153252d5613