Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Veronica, Di Paolo"'
Autor:
Francesco Piazza, Veronica Di Paolo, Greta Scapinello, Sabrina Manni, Livio Trentin, Luigi Quintieri
Publikováno v:
Frontiers in Oncology, Vol 11 (2022)
Lymphoplasmacytic lymphoma (LPL) is a rare subtype of B cell-derived non-Hodgkin lymphoma characterized by the abnormal growth of transformed clonal lymphoplasmacytes and plasma cells. This tumor almost always displays the capability of secreting lar
Externí odkaz:
https://doaj.org/article/68b4f7f5e3854d7bbb0ae40f95bc12b1
Autor:
Veronica Di Paolo, Chiara Fulci, Dante Rotili, Francesca Sciarretta, Alessia Lucidi, Blasco Morozzo della Rocca, Anastasia De Luca, Antonio Rosato, Luigi Quintieri, Anna Maria Caccuri
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1131-1139 (2019)
The antitumor agent 6-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)hexan-1-ol (1) is a potent inhibitor of GSTP1-1, a glutathione S-transferase capable of inhibiting apoptosis by binding to JNK1 and TRAF2. We recently demonstrated that, unlike its par
Externí odkaz:
https://doaj.org/article/7658832476ab4c16a9cb9de4edf953e6
Autor:
Giulia Siciliano, Veronica Di Paolo, Dante Rotili, Rossella Migale, Francesca Pedini, Marialuisa Casella, Serena Camerini, Daniele Dalzoppo, Rob Henderson, Tonnie Huijs, Koen J. Dechering, Antonello Mai, Anna Maria Caccuri, Marco Lalle, Luigi Quintieri, Pietro Alano
Publikováno v:
Pharmaceuticals, Vol 15, Iss 2, p 168 (2022)
This work describes the activity of 6-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)hexan-1-ol (NBDHEX) and of its newly identified carboxylic acid metabolite on the human malaria parasite Plasmodium falciparum. NBDHEX has been previously identified as
Externí odkaz:
https://doaj.org/article/a949dc021e86479e8207123ad14c5b58
Publikováno v:
Diagnostics, Vol 11, Iss 6, p 1118 (2021)
Extracellular vesicles (EVs) are important mediators of intercellular communication playing a pivotal role in the regulation of physiological and pathological processes, including cancer. In particular, there is significant evidence suggesting that t
Externí odkaz:
https://doaj.org/article/59b816564d4e4dd7821018ef6db22065
Autor:
Chiara Fulci, Dante Rotili, Anastasia De Luca, Lorenzo Stella, Blasco Morozzo della Rocca, Mariantonietta Forgione, Veronica Di Paolo, Antonello Mai, Mattia Falconi, Luigi Quintieri, Anna M. Caccuri
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 240-247 (2017)
Context: The nitrobezoxadiazole derivative NBDHEX is a potent inhibitor of glutathione transferase P1-1 (GSTP1-1) endowed with outstanding anticancer activity in different tumor models. Objective: To characterize by in vitro biochemical and in silico
Externí odkaz:
https://doaj.org/article/3789f8d2549b4ac8b31477f4b3596ba3
Numerous drugs have the potential to be affected by cytochrome P450 (CYP) 2B6-mediated drug-drug interactions (DDIs).In this work, we extend a static approach to the prediction of the extent of pharmacokinetics DDIs between substrates and inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afbacafb9e77af3cd102c0f4ca6c1fc2
http://hdl.handle.net/11577/3454260
http://hdl.handle.net/11577/3454260
Autor:
Giulia, Siciliano, Veronica, Di Paolo, Dante, Rotili, Rossella, Migale, Francesca, Pedini, Marialuisa, Casella, Serena, Camerini, Daniele, Dalzoppo, Rob, Henderson, Tonnie, Huijs, Koen J, Dechering, Antonello, Mai, Anna Maria, Caccuri, Marco, Lalle, Luigi, Quintieri, Pietro, Alano
Publikováno v:
Pharmaceuticals (Basel, Switzerland). 15(2)
This work describes the activity of 6-((7-nitrobenzo[
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::532ddfcccdec0b928fabd6db1cb7fa38
https://pubmed.ncbi.nlm.nih.gov/35215282
https://pubmed.ncbi.nlm.nih.gov/35215282
Autor:
Francesco Piazza, Veronica Di Paolo, Greta Scapinello, Sabrina Manni, Livio Trentin, Luigi Quintieri
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 11 (2022)
Frontiers in Oncology, Vol 11 (2022)
Lymphoplasmacytic lymphoma (LPL) is a rare subtype of B cell-derived non-Hodgkin lymphoma characterized by the abnormal growth of transformed clonal lymphoplasmacytes and plasma cells. This tumor almost always displays the capability of secreting lar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::891cc71c56becc8ddc5ab81f189b3037
https://pubmed.ncbi.nlm.nih.gov/35087759
https://pubmed.ncbi.nlm.nih.gov/35087759
Autor:
Gabriele Stocco, Luigi Quintieri, Marianna Lucafò, Giuliana Decorti, Marco Pelin, Veronica Di Paolo, Elena Genova
Publikováno v:
Chemico-biological interactions. 347
Thiopurines, immunomodulating drugs used in the management of different chronic autoimmune conditions and as anti-leukemic agents, may exert in some cases gastrointestinal toxicity. Moreover, since these agents are administered orally, they are absor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d446abca77d967d6aac8068932496508
https://pubmed.ncbi.nlm.nih.gov/34416244
https://pubmed.ncbi.nlm.nih.gov/34416244
Autor:
Laura Calderan, Stefano Moro, Veronica Di Paolo, Maria Grazia Ferlin, Mattia Sturlese, Matteo Dal Pra, Davide Carta, Roberta Bortolozzi, Elena Mattiuzzo, Ernest Hamel, Giampietro Viola, Roberto Ronca, Giuseppe Antoniazzi, Luigi Quintieri
A small number of fluorinated 7-phenyl-pyrroloquinolinone (7-PPyQ) derivatives was synthesized in an attempt to improve the metabolic stability of 3N-ethyl-7-PPyQ and 3N-benzoyl-7-PPyQ. The possible impacts of the fluorine-hydrogen isosterism on both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf0876d5db277bd3407b21ac983be5f9
http://hdl.handle.net/11577/3303577
http://hdl.handle.net/11577/3303577