Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Vernon T. Oi"'
Autor:
Sherie L. Morrison, Stephen B. Porter, K. Ryan Trinh, Letitia A. Wims, Jerrod Denham, Vernon T. Oi
Publikováno v:
The Journal of Immunology. 160:2802-2808
In the present study we have characterized a family of anti-dansyl Abs with the variable region of the heavy chain on human Cκ and the variable region of the light chain on different human γ constant regions (creating inside-out molecules). Althoug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54aec9af14f84a67d121e452b4b7b305
https://doi.org/10.4049/jimmunol.160.6.2802
https://doi.org/10.4049/jimmunol.160.6.2802
Publikováno v:
Molecular Immunology. 30:797-804
Structural similarities between two members of the immunoglobulin superfamily were explored by making chimeric immunoglobulin/CD4 antigen molecules. A crossover in the middle of the originally proposed J kappa homology unit of the first domain of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d24cd51ee68685bec4d97d5c1942a74d
https://doi.org/10.1016/0161-5890(93)90002-s
https://doi.org/10.1016/0161-5890(93)90002-s
Publikováno v:
Molecular immunology. 27(2)
We have studied by electron microscopy a fascinating series of antidansyl monoclonal antibodies developed by Dangl et al. (Cytometry 2, 395-401, 1982) which have the same variable domain but different constant domains. Three of the four subclasses of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6315f8f13b2f0bb59faf182f1cd5a398
https://pubmed.ncbi.nlm.nih.gov/2320011
https://pubmed.ncbi.nlm.nih.gov/2320011
We have characterized a series of genetically engineered chimeric human IgG3 and IgG4 anti-dansyl (DNS) antibodies with identical antibody-combining sites but different hinge region amino acid compositions to determine how the hinge region influences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a72a2913febd56ba371c928ad88d8c47
https://europepmc.org/articles/PMC53220/
https://europepmc.org/articles/PMC53220/
Publikováno v:
Cancer Investigation. 6:185-192
(1988). Genetically Engineered Antibody Molecules: New Tools for Cancer Therapy. Cancer Investigation: Vol. 6, No. 2, pp. 185-192.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e5bf1e5b89feb932d85e308dee1e7e
https://doi.org/10.3109/07357908809077046
https://doi.org/10.3109/07357908809077046
Autor:
David Holowka, Robert J. Shopes, Patricia M. Kane, Barbara Baird, Vernon T. Oi, Jon D. Erickson
Publikováno v:
International Archives of Allergy and Immunology. 88:23-28
Structural interactions between IgE and its high-affinity receptor have been investigated with the methods of fluorescence resonance energy transfer and genetic engineering. The results indicate that IgE has a bent conformation when bound to receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15035781b1ecf2df0633ac6aaa4687c6
https://doi.org/10.1159/000234742
https://doi.org/10.1159/000234742
Publikováno v:
Proceedings of the National Academy of Sciences. 81:6851-6855
We have created mouse-human antibody molecules of defined antigen-binding specificity by taking the variable region genes of a mouse antibody-producing myeloma cell line with known antigen-binding specificity and joining them to human immunoglobulin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a7b4a9ee1d2495b374e67afd09ce7c
https://doi.org/10.1073/pnas.81.21.6851
https://doi.org/10.1073/pnas.81.21.6851
Publikováno v:
Immunogenetics. 18:311-321
We have generated a new series of monoclonal antibodies recognizing allotypic determinants on mouse IgG1, IgG2a, and IgG2b. In this communication we describe their reactivity at the molecular level. A number of genetic specificities (as defined by re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e531933a0591dd9f5b67b5d3fd832da
https://doi.org/10.1007/bf00372464
https://doi.org/10.1007/bf00372464
Autor:
J Dangle, Lubert Stryer, J Reidler, T M Vuong, Vernon T. Oi, Leonore A. Herzenberg, Richard R. Hardy
Publikováno v:
Nature. 307:136-140
Mouse monoclonal anti-dansyl antibodies with the same antigen-binding sites but different heavy chain constant regions were generated. The extent of segmental flexibility in times of nanoseconds and the capacity to fix complement were greatest for Ig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f11ef128a1893faa85d14f9bd22f68
https://doi.org/10.1038/307136a0
https://doi.org/10.1038/307136a0