Výsledky vyhledávání - "Vernon M. Coffield"

Fostering Equitable Outcomes in Introductory Biology Courses through Use of a Dual Domain Pedagogy

Autor: Patrick A. Vigueira, Vernon M. Coffield, Kevin Suh, Dinene Crater, Todd A. Lyda, Angela C. Bauer, Verónica A. Segarra, Cynthia C. Vigueira

Publikováno v: CBE Life Sciences Education

Recent studies demonstrate that significant learning gains can be achieved when instructors take intentional steps to address the affective components of learning. While such efforts enhance the outcomes of all students, they are particularly benefic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f992aef6061b7d037cf40fba3871fa4
https://doi.org/10.1187/cbe.19-07-0134

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hDOT1L links histone methylation to leukemogenesis

Autor: Yaqiang Li, Lishan Su, Qi Jiang, Vernon M. Coffield, Yihui Lin, Yi Zhang, Yuki Okada, Qin Feng, Guoliang Xu

Publikováno v: Cell. 121(2)

SummaryEpigenetic modifications play an important role in human cancer. One such modification, histone methylation, contributes to human cancer through deregulation of cancer-relevant genes. The yeast Dot1 and its human counterpart, hDOT1L, methylate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26e09045c537ca0329ba55db2ef69504
https://pubmed.ncbi.nlm.nih.gov/15851025

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Regulation of the hematopoietic stem/progenitor cell subsets in mouse bone marrow by the cdk inhibitor p18INK4c

Autor: Tamara D. Simon, Grigoriy I. Kovalev, Vernon M. Coffield, Lishan Su

Publikováno v: Experimental Hematology. 28:1494

Although the majority of hematopoietic stem cells (HSC) is quiescent in adult mouse bone marrow, all HSC are recruited into cycle regularly. Thus, HSC repeatedly enter and exit the cell cycle. Activation of quiescent cells requires D type cyclins in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6112ff9a97de46644d5f4c65eae36f45
https://doi.org/10.1016/s0301-472x(00)00567-1

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Thymic pathogenicity of an HIV-1 envelope is associated with increased CXCR4 binding efficiency and V5-gp41-dependent activity, but not V1/V2-associated CD4 binding efficiency and viral entry

Autor: Lishan Su, Eric G. Meissner, Vernon M. Coffield

Publikováno v: Virology. (2):184-197

We previously described a thymus-tropic HIV-1 envelope (R3A Env) from a rapid progressor obtained at the time of transmission. An HIV-1 molecular recombinant with the R3A Env supported extensive replication and pathogenesis in the thymus and did not

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b4ad0a97f27a92f4ae5a2482fed3807

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