Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Vernon M. Camp"'
Autor:
Zhaobin Zhang, Jeffrey J. Olson, Mark M. Goodman, Vernon M. Camp, Lawrence E. Williams, Jonathan McConathy, Eugene Malveaux, Weiping Yu
Publikováno v:
Journal of Medicinal Chemistry. 53:876-886
The non-natural amino acids (R)- and (S)-2-amino-3-fluoro-2-methylpropanoic acid 5 and (R)- and (S)-3-fluoro-2-methyl-2-N-(methylamino)propanoic acid 8 were synthesized in shorter reaction sequences than in the original report starting from enantiome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa533d13af123001b1d888e4cd121e38
https://doi.org/10.1021/jm900556s
https://doi.org/10.1021/jm900556s
Autor:
J D Bremner, Clinton D. Kilts, Nachwa Jarkas, David Purselle, Charles B. Nemeroff, Vernon M. Camp, Mark M. Goodman, Jonathon A. Nye, John R. Votaw
Publikováno v:
Journal of Nuclear Medicine. 49:2018-2025
The novel PET radioligand 11C-N,N-dimethyl-2-(2′-amino-4′-hydroxymethylphenylthio)benzylamine (11C-HOMADAM) binds with high affinity and selectively to the serotonin transporter (SERT). The purpose of this study was to develop a reliable kinetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8682bf99d59abe30eb2fd15da2540143
https://doi.org/10.2967/jnumed.108.054262
https://doi.org/10.2967/jnumed.108.054262
Autor:
Nachwa Jarkas, Eugene J. Malveaux, Michael J. Owens, Vernon M. Camp, Leonard L. Howell, Ronald Voll, Jeffrey S. Stehouwer, Mark M. Goodman, Larry A Williams, John Votaw, Fanxing Zeng
Publikováno v:
Journal of Medicinal Chemistry. 49:6760-6767
2beta-carbomethoxy-3beta-(3'-((Z)-2-iodoethenyl)phenyl)nortropane (mZIENT, 1) and 2beta-carbomethoxy-3beta-(3'-((Z)-2-bromoethenyl)phenyl)nortropane (mZBrENT, 2) were synthesized and evaluated for binding to the human serotonin, dopamine, and norepin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8262054a723f8ab7c26918a6601a8a6f
https://doi.org/10.1021/jm060641q
https://doi.org/10.1021/jm060641q
Autor:
Xiaojian Wang, Niren Murthy, Vernon M. Camp, Lawrence E. Williams, Mark M. Goodman, Seungjun Lee, W. Robert Taylor, Daiana Weiss, Malveaux Eugene, Kiyoko Takemiya, Xuli Feng, Xinghai Ning, Mohammad A. Rafi, Wonewoo Seo
Publikováno v:
Angewandte Chemie (International ed. in English), vol 53, iss 51
A positron emission tomography (PET) tracer composed of (18)F-labeled maltohexaose (MH(18)F) can image bacteria in vivo with a sensitivity and specificity that are orders of magnitude higher than those of fluorodeoxyglucose ((18)FDG). MH(18)F can det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f2b1dded246392943f9c0bcec919b5a
https://escholarship.org/uc/item/1r0540c5
https://escholarship.org/uc/item/1r0540c5
Autor:
Robin R. Goodman, John R. Votaw, Vernon M. Camp, Mark M. Goodman, Eugene Malveaux, Lawrence E. Williams, Jonathan McConathy, Nachwa Jarkas, Ronald J. Voll, Clinton D. Kilts
Publikováno v:
Nuclear Medicine and Biology. 32:75-86
[ 11 C] N , N -Dimethyl-2-(2′-amino-4′-ethylphenylthio)benzylamine ([ 11 C]EADAM) was synthesized in the development of a serotonin transporter (SERT) imaging ligand for positron emission tomography (PET). The methods of ligand synthesis, results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c43f38814e2d3fd908674f70d2774630
https://doi.org/10.1016/j.nucmedbio.2004.07.001
https://doi.org/10.1016/j.nucmedbio.2004.07.001
Autor:
Jonathan McConathy, Nicholas E. Simpson, Eugene Malveaux, Vernon M. Camp, Laurent Martarello, Geoffrey Bowers, Mark M. Goodman, Jeffrey J. Olson, Chiab P. Simpson
Publikováno v:
Journal of Medicinal Chemistry. 45:2250-2259
syn- and anti-1-amino-3-[18F]fluoromethyl-cyclobutane-1-carboxylic acid (FMACBC, 16 and 17), analogues of anti-1-amino-3-[18F]fluorocyclobutyl-1-carboxylic acid (FACBC), were prepared to evaluate the contributions of C-3 substitution and configuratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a0b77908fd3d82c78348a6e99d56f4
https://doi.org/10.1021/jm010242p
https://doi.org/10.1021/jm010242p
Autor:
Margaret R. Davis, Gene Malveaux, Vernon M. Camp, Robert Keil, Clinton D. Kilts, Mark M. Goodman, Roy A.E. Bakay, Dongxia Xing, Ping Chen, Timothy D. Ely, Ray L. Watts, John R. Votaw, Bing Shi, Michael J. Owens, Thygarajan Subramanian, John M. Hoffman
Publikováno v:
Journal of Medicinal Chemistry. 43:639-648
2beta-(R)-Carbo-1-fluoro-2-propoxy-3beta-(4-chlorophenyl) tro pane ((R)-FIPCT, R-6) and 2beta-(S)-carbo-1-fluoro-2-propoxy-3beta-(4-chlorophenyl) tro pane ((S)-FIPCT, S-6) were prepared and evaluated in vitro and in vivo for dopamine transporter (DAT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2867b2a6f6518c6fddbd4609dbd1ad9a
https://doi.org/10.1021/jm9902234
https://doi.org/10.1021/jm9902234
Autor:
Bing Shi, Timothy D. Ely, Mark M. Goodman, John M. Hoffman, John R. Votaw, Michael J. Owens, Vernon M. Camp, Robert Keil, Eugene Malveaux, Dongxia Xing, Clinton D. Kilts, Philip D. Lambert, Laurent Martarello
Publikováno v:
Nuclear Medicine and Biology. 27:1-12
Fluorine-18 labeled 2beta-carbomethoxy-3beta-(4-chlorophenyl)-8-(2-fluoroethyl)nort ropane (FECNT) was synthesized in the development of a dopamine transporter (DAT) imaging ligand for positron emission tomography (PET). The methods of radiolabeling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49e9547379ce816d517c6dde515fb9ef
https://doi.org/10.1016/s0969-8051(99)00080-3
https://doi.org/10.1016/s0969-8051(99)00080-3
Autor:
Vernon M. Camp, J. Douglas Bremner, Margaret R. Davis, John R. Votaw, Mark M. Goodman, Ronald J. Voll, Jonathon A. Nye
Publikováno v:
Nuclear medicine and biology. 41(3)
Fluorine-18 labeled 2β-carbomethoxy-3β-(4-chlorophenyl)-8-(2-fluoroethyl)nortropane ([(18)F]FECNT) binds reversibly to the dopamine transporter (DAT) with high selectivity. [(18)F]FECNT has been used extensively in the quantification of DAT occupan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc464309f264b5d1fe8a6529bbf8bee1
https://pubmed.ncbi.nlm.nih.gov/24533985
https://pubmed.ncbi.nlm.nih.gov/24533985
Autor:
Francois Villinger, Jyotirmay Sharma, Raghuveer Halkar, Praveen K. Amancha, Kereen Gordon, Susan Muller, Philip S. Low, Roger Schibli, Cristina Müller, Malgorzata Lipowska, Vernon M. Camp, Susan A. Safley, Christopher P. Leamon, Collin J. Weber
Publikováno v:
Surgery. 154(6)
Background Human pituitary adenomas express folate receptors (FR); therefore, we hypothesized that parathyroid (PT) tumors also might express FR, whereas normal human thyroids might not. The purpose of our study was to characterize the functionality
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33352cae67d1df4fac6647ea3353afd6
https://pubmed.ncbi.nlm.nih.gov/24206618
https://pubmed.ncbi.nlm.nih.gov/24206618