Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Vernon J. Feil"'
Publikováno v:
Xenobiotica. 31:443-455
1. [UL-7,8-ring 14C]-1,2,7,8-tetrachlorodibenzo-p-dioxin (1278-TCDD) was administered orally to a ruminating Holstein bull calf (43.6 kg; 1.2 mg kg-1 body weight). Urine and faeces were collected daily for 96 h, while blood was sampled at multiple ti
Autor:
T.O. Tiernan, Vernon L. Anderson, Janice K. Huwe, Vernon J. Feil, Richard G. Zaylskie, Martin J. Marchello, Kenneth L. Davison
Publikováno v:
Journal of Agricultural and Food Chemistry. 48:6163-6173
Four calves were fed polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans for 120 days at levels somewhat higher than what may be found in forage near some waste incinerators and manufacturing plants. Four calves were fed identical die
Publikováno v:
Chemosphere. 40:957-962
The in vivo formation of dioxins from chemical precursors was investigated in rats. Sprague-Dawley rats were fed pentachlorophenol or a predioxin in peanut oil for 14 days. Mass balance calculations indicated that pentachlorophenol was not converted
Publikováno v:
Xenobiotica. 30:427-440
1. The bile duct cannulated turkey poult (n = 3) dosed orally with [14C]ractopamine HCl [(1R*,3R*),(1R*,3S*)-4-hydroxy-alpha-[[[3-(4-hydroxy[14C]phenyl)-1-methy lpropyl]amino]methyl]-benzenemethanol hydrochloride; 19.9 mg; 9.28 microCi] excreted 37.4
Publikováno v:
Chemosphere. 37:1885-1893
Metabolism studies of 1,4,7,8-tetrachlorodibenzo p -dioxin (TCDD), a relatively nontoxic dioxin congener, were undertaken to gain a better understanding of mammalian metabolism of dioxins without the problems associated with the use of the most toxic
Publikováno v:
Journal of Agricultural and Food Chemistry. 46:3280-3284
Human exposure to the environmental pollutants in the polychlorinated dibenzodioxin and dibenzofuran classes is mainly through bioaccumulation of residues in animal food products. Estimates of risk require detailed knowledge of diet, consumption patt
Autor:
Vernon J. Feil
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 38:1071-1076
The syntheses of 14 C-ring labeled levamisole ([-]-2,3,5,6-tetrahydro-6-phenyl[ 14 C-UL]imidazo[2,1-b]thiazole) from acetophenone-ring-UL- 14 C in 5 steps plus resolution with a 7.5% overall field, and 13 C 6 -ring labeled tetramisole ([±]-2,3,5,6-t
Publikováno v:
Xenobiotica. 26:921-933
1. 14C-sulphadimethoxine (4-amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzene-[U-14C]-sulphonamide; 14C-SDM) was given orally (60 mg/kg body weight) to eight swine (weight 27-32 kg). Urine and faeces were collected from 0 to 72 h after dosing and tissue s
Publikováno v:
Journal of Agricultural and Food Chemistry. 43:2970-2973
Disposition of oral sulfathiazole was studied in swine. Pigs were slaughtered 6, 12, 24, and 48 h after an oral dose of [ 14 C]sulfathiazole (two at each time period). Excretion of 14 C was rapid (>90% in 48 h), primarily via the urine. Metabolites i
Publikováno v:
Xenobiotica. 25:511-520
1. Rats dosed orally with 2.85 +/- 0.30 mg [14C]ractopamine HC1 [(1R*, 3R*), (1R*, 3S*)-4-hydroxy-alpha-[[[3-(4-hydroxyphenyl)- 1-methylpropyl]-amino]-methyl]([U-14C]benzenemethanol)hydrochloride] containing 1.44 +/- 0.15 microCi radioactivity excret