Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Verne A. Ray"'
Autor:
Austin J. Joyce, Margitta G. Wahrenburg, Paula A. Muehlbauer, Verne A. Ray, Henry E. Holden, Gail N. Turner, David E. Amacher, John H. Ellis
Publikováno v:
Mutation Research/Genetic Toxicology. 300:79-90
Azithromycin was subjected to a series of three in vitro and one in vivo genetic toxicology assays for the detection of drug-associated gene or chromosomal effects. In the Ames Salmonella typhimurium tester strains TA1535, TA1537, TA98 and TA100, the
Publikováno v:
Mutation Research/Environmental Mutagenesis and Related Subjects. 64:391-406
We have systematically evaluated the mouse lymphoma TK+/- leads to TK-/- mutagenesis assay to determine if this somatic-cell test system would be a useful addition to the routine screening battery already used in our laboratory for the detection of c
Publikováno v:
Journal of Toxicology and Environmental Health. 1:211-227
Oxamniquine (UK-4271; 6-hydroxymethyl-2-isopropylaminomethyl-7-nitro-1,2,3,4-tetrahydroquinoline) is a new schistosomicidal agent currently undergoing clinical investigation in South America. Essentially a complete cure rate against Brazilian Schisto
Autor:
R. McGaughy, Verne A. Ray, Hinda Bergman, M. Argus, K. Chu, C. Frith, Thomas J. Slaga, Raymond W. Tennant, Stephen Nesnow, E. Weisburger, T. Helmes
Publikováno v:
Mutation Research/Reviews in Genetic Toxicology. 185:1-195
The literature on 506 selected chemicals has been evaluated for evidence that these chemicals induce tumors in experimental animals and this assessment comprises the Gene-Tox Carcinogen Data Base. Three major sources of information were used to creat
Autor:
David Brusick, T.K. Rao, V.F. Simmon, Verne A. Ray, Joyce McCann, E.S. Von Halle, M.M. Brown, L.E. Kier, Angela E. Auletta, Virginia C. Dunkel, Kristien Mortelmans, Michael J. Prival
Publikováno v:
Mutation Research/Reviews in Genetic Toxicology. 168:69-240
The Salmonella assay has been in use for almost 15 years and can be defined as a routine test for mutagenicity and for predicting potential carcinogenicity. It detects the majority of animal carcinogens and consequently plays an important role in saf
Autor:
Stephen Nesnow, J.S. Wassom, L.D. Kier, Angela E. Auletta, Michael D. Waters, K.L. Kannan, Verne A. Ray, R.T. Haas
Publikováno v:
Mutation Research/Reviews in Genetic Toxicology. 185:197-241
This report of the Gene-Tox Assessment Panel is a compilation of data that documents the chemical testing efforts in genetic toxicology through mid-1979. It thus provides an historical perspective of the major efforts in this field and the utility of
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 20:257-263
Cytogenetic studies have been performed to determine the effect of 6-mercaptopurine (6-MP) on mammalian chromosomes in vivo . An elevated level of chromosome breakage is present in mouse bone marrow cells within 12 h after oral or parenteral dosing w
Publikováno v:
Toxicology and Applied Pharmacology. 30:107-116
Recent reports have advocated the use of a battery of tests for evaluating the mutagenic potential of chemicals. The present study was undertaken to compare three such procedures: the host-mediated, the dominant lethal, and the in vivo cytogenetic as
Autor:
Verne F. Ray
Publikováno v:
American Anthropologist. 38:67-75
Autor:
Verne F. Ray
Publikováno v:
Southwestern Journal of Anthropology. 8:251-259