Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Verna Salo"'
Autor:
Subhash K. Tripathi, Tommi Välikangas, Ankitha Shetty, Mohd Moin Khan, Robert Moulder, Santosh D. Bhosale, Elina Komsi, Verna Salo, Rafael Sales De Albuquerque, Omid Rasool, Sanjeev Galande, Laura L. Elo, Riitta Lahesmaa
Publikováno v:
iScience, Vol 11, Iss , Pp 334-355 (2019)
Summary: Th17 cells contribute to the pathogenesis of inflammatory and autoimmune diseases and cancer. To reveal the Th17 cell-specific proteomic signature regulating Th17 cell differentiation and function in humans, we used a label-free mass spectro
Externí odkaz:
https://doaj.org/article/a33e53201c9e49cfa508eb772af0ab8f
Autor:
Subhash K. Tripathi, Zhi Chen, Antti Larjo, Kartiek Kanduri, Kari Nousiainen, Tarmo Äijo, Isis Ricaño-Ponce, Barbara Hrdlickova, Soile Tuomela, Essi Laajala, Verna Salo, Vinod Kumar, Cisca Wijmenga, Harri Lähdesmäki, Riitta Lahesmaa
Publikováno v:
Cell Reports, Vol 19, Iss 9, Pp 1888-1901 (2017)
The development of therapeutic strategies to combat immune-associated diseases requires the molecular mechanisms of human Th17 cell differentiation to be fully identified and understood. To investigate transcriptional control of Th17 cell differentia
Externí odkaz:
https://doaj.org/article/d673990638a54d0f83990621f297efa2
Methods for time series analysis of RNA-seq data with application to human Th17 cell differentiation
Autor:
Riitta Lahesmaa, Verna Salo, Zhi Jane Chen, Harri Lähdesmäki, Subhash K. Tripathi, Tarmo Äijö, Vincent L. Butty, Christopher B. Burge
Publikováno v:
Bioinformatics
Motivation: Gene expression profiling using RNA-seq is a powerful technique for screening RNA species’ landscapes and their dynamics in an unbiased way. While several advanced methods exist for differential expression analysis of RNA-seq data, prop
Autor:
Riitta Lahesmaa, Tarmo Äijö, Harri Lähdesmäki, Verna Salo, Brigitta Stockinger, Kirsti Laurila, Soile Tuomela, Subhash K. Tripathi, Lotta E. Oikari, Bhawna Gupta, Zhi Chen
Publikováno v:
Blood. 119:e151-e160
Th17 cells play an essential role in the pathogenesis of autoimmune and inflammatory diseases. Most of our current understanding on Th17 cell differentiation relies on studies carried out in mice, whereas the molecular mechanisms controlling human Th
Autor:
Soile, Tuomela, Sini, Rautio, Helena, Ahlfors, Viveka, Öling, Verna, Salo, Ubaid, Ullah, Zhi, Chen, Saara, Hämälistö, Subhash K, Tripathi, Tarmo, Äijö, Omid, Rasool, Hayssam, Soueidan, Lodewyk, Wessels, Brigitta, Stockinger, Harri, Lähdesmäki, Riitta, Lahesmaa
Publikováno v:
Oncotarget
Uncontrolled Th17 cell activity is associated with cancer and autoimmune and inflammatory diseases. To validate the potential relevance of mouse models of targeting the Th17 pathway in human diseases we used RNA sequencing to compare the expression o