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An evaluation of the emerging interventions against Respiratory Syncytial Virus (RSV)-associated acute lower respiratory infections in children

Autor: Simões Eric AF, Huda Tanvir, Zgaga Lina, Theodoratou Evropi, Verma Vasundhara R, Nair Harish, Wright Peter F, Rudan Igor, Campbell Harry

Publikováno v: BMC Public Health, Vol 11, Iss Suppl 3, p S30 (2011)

Abstract Background Respiratory Syncytial Virus (RSV) is the leading cause of acute lower respiratory infections (ALRI) in children. It is estimated to cause approximately 33.8 million new episodes of ALRI in children annually, 96% of these occurring

Externí odkaz: https://doaj.org/article/e41a75b4eb464c4f87e0c7915b6da3af

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Akademický článek

Novel indolo [3,2-c]isoquinoline-5-one-6-yl [1,2,4]triazolo [3,4-b] [1,3,4]thiadiazole analogues: Design, synthesis, anticancer activity, docking with SARS-CoV-2 Omicron protease and MESP/TD-DFT approaches.

Autor: Verma VA; Department of Chemistry, Sri Prabhu Arts, Science and J. M. Bohra Commerce Degree College, Shorapur-585 224, Yadgir, Karnataka, India., Saundane AR; Department of P.G. Studies and Research in Chemistry, Gulbarga University, Kalaburagi, 585106, Karnataka, India., Shamrao R; Department of Chemistry, Government First Grade College, Shahapur-585 223, Yadgir, Karnataka, India., Meti RS; Department of Biochemistry, Mangalore University, P.G. Centre Chikka Aluvara, 571234, Karnataka, India., Shinde VM; Department of Botany, Gulbarga University, Kalaburagi, Karnataka, 585 106, India.

Publikováno v: Journal of molecular structure [J Mol Struct] 2022 Sep 15; Vol. 1264, pp. 133153. Date of Electronic Publication: 2022 Apr 25.

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Akademický článek

Discovery of Inhibitors of the Lipopolysaccharide Transporter MsbA: From a Screening Hit to Potent Wild-Type Gram-Negative Activity.

Autor: Verma VA; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Wang L; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Labadie SS; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Liang J; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Sellers BD; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Wang J; WuXi AppTec Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China., Dong L; WuXi AppTec Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China., Wang Q; WuXi AppTec Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China., Zhang S; WuXi AppTec Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China., Xu Z; WuXi AppTec Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China., Zhang Y; WuXi AppTec Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China., Niu Y; WuXi AppTec Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China., Wang X; WuXi AppTec Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China., Wai J; WuXi AppTec Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China., Koehler MFT; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Hu H; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Alexander MK; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Nishiyama M; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Miu A; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Xu Y; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Pang J; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Katakam AK; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Reichelt M; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Austin CD; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Ho H; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Payandeh J; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Koth CM; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2022 Mar 10; Vol. 65 (5), pp. 4085-4120. Date of Electronic Publication: 2022 Feb 20.

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Akademický článek

Synthesis of novel indolo[3,2-c]isoquinoline derivatives bearing pyrimidine, piperazine rings and their biological evaluation and docking studies against COVID-19 virus main protease.

Autor: Verma VA; Department of Chemistry, Shri Prabhu Arts, Science and J.M. Bohra Commerce, Degree College, Shorapur-585 228, Yadgir, Karnataka, India., Saundane AR; Department of P.G. Studies and Research in Chemistry, Gulbarga University, Kalaburagi 585106, Karnataka, India., Meti RS; Department of Biochemistry, Mangalore University, P.G. Centre Chikka, Aluvara 571234, Karnataka, India., Vennapu DR; Department of Pharmaceutical Chemistry, KLE University College of Pharmacy, Belagavi 5900010, Karnataka, India.

Publikováno v: Journal of molecular structure [J Mol Struct] 2021 Apr 05; Vol. 1229, pp. 129829. Date of Electronic Publication: 2020 Dec 27.

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