Zobrazeno 1 - 10 of 182 pro vyhledávání: '"Verma VA"'
1
Akademický článek
Novel indolo [3,2-c]isoquinoline-5-one-6-yl [1,2,4]triazolo [3,4-b] [1,3,4]thiadiazole analogues: Design, synthesis, anticancer activity, docking with SARS-CoV-2 Omicron protease and MESP/TD-DFT approaches.
Autor: Verma VA; Department of Chemistry, Sri Prabhu Arts, Science and J. M. Bohra Commerce Degree College, Shorapur-585 224, Yadgir, Karnataka, India., Saundane AR; Department of P.G. Studies and Research in Chemistry, Gulbarga University, Kalaburagi, 585106, Karnataka, India., Shamrao R; Department of Chemistry, Government First Grade College, Shahapur-585 223, Yadgir, Karnataka, India., Meti RS; Department of Biochemistry, Mangalore University, P.G. Centre Chikka Aluvara, 571234, Karnataka, India., Shinde VM; Department of Botany, Gulbarga University, Kalaburagi, Karnataka, 585 106, India.
Publikováno v: Journal of molecular structure [J Mol Struct] 2022 Sep 15; Vol. 1264, pp. 133153. Date of Electronic Publication: 2022 Apr 25.
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2
Akademický článek
Discovery of Inhibitors of the Lipopolysaccharide Transporter MsbA: From a Screening Hit to Potent Wild-Type Gram-Negative Activity.
Autor: Verma VA; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Wang L; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Labadie SS; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Liang J; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Sellers BD; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Wang J; WuXi AppTec Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China., Dong L; WuXi AppTec Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China., Wang Q; WuXi AppTec Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China., Zhang S; WuXi AppTec Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China., Xu Z; WuXi AppTec Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China., Zhang Y; WuXi AppTec Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China., Niu Y; WuXi AppTec Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China., Wang X; WuXi AppTec Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China., Wai J; WuXi AppTec Co., Ltd., 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, People's Republic of China., Koehler MFT; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Hu H; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Alexander MK; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Nishiyama M; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Miu A; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Xu Y; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Pang J; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Katakam AK; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Reichelt M; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Austin CD; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Ho H; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Payandeh J; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States., Koth CM; Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2022 Mar 10; Vol. 65 (5), pp. 4085-4120. Date of Electronic Publication: 2022 Feb 20.
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3
Akademický článek
Synthesis of novel indolo[3,2-c]isoquinoline derivatives bearing pyrimidine, piperazine rings and their biological evaluation and docking studies against COVID-19 virus main protease.
Autor: Verma VA; Department of Chemistry, Shri Prabhu Arts, Science and J.M. Bohra Commerce, Degree College, Shorapur-585 228, Yadgir, Karnataka, India., Saundane AR; Department of P.G. Studies and Research in Chemistry, Gulbarga University, Kalaburagi 585106, Karnataka, India., Meti RS; Department of Biochemistry, Mangalore University, P.G. Centre Chikka, Aluvara 571234, Karnataka, India., Vennapu DR; Department of Pharmaceutical Chemistry, KLE University College of Pharmacy, Belagavi 5900010, Karnataka, India.
Publikováno v: Journal of molecular structure [J Mol Struct] 2021 Apr 05; Vol. 1229, pp. 129829. Date of Electronic Publication: 2020 Dec 27.
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4
Akademický článek
A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment.
Autor: Balestrini A; Department of Immunology Discovery, Genentech, Inc., South San Francisco, CA., Joseph V; Department of Biomedical Imaging, Genentech, Inc., South San Francisco, CA., Dourado M; Department of Neuroscience, Genentech, Inc., South San Francisco, CA., Reese RM; Department of Neuroscience, Genentech, Inc., South San Francisco, CA., Shields SD; Department of Neuroscience, Genentech, Inc., South San Francisco, CA., Rougé L; Department of Structural Biology, Genentech, Inc., South San Francisco, CA., Bravo DD; Department of Biochemical and Cellular Pharmacology, Genentech, Inc., South San Francisco, CA., Chernov-Rogan T; Department of Biochemical and Cellular Pharmacology, Genentech, Inc., South San Francisco, CA., Austin CD; Department of Pathology, Genentech, Inc., South San Francisco, CA., Chen H; Department of Discovery Chemistry, Genentech, Inc., South San Francisco, CA., Wang L; Department of Discovery Chemistry, Genentech, Inc., South San Francisco, CA., Villemure E; Department of Discovery Chemistry, Genentech, Inc., South San Francisco, CA., Shore DGM; Department of Discovery Chemistry, Genentech, Inc., South San Francisco, CA., Verma VA; Department of Discovery Chemistry, Genentech, Inc., South San Francisco, CA., Hu B; Pharmaron-Beijing Co. Ltd., BDA, Beijing, People's Republic of China., Chen Y; Pharmaron-Beijing Co. Ltd., BDA, Beijing, People's Republic of China., Leong L; Department of Pathology, Genentech, Inc., South San Francisco, CA., Bjornson C; Department of Pathology, Genentech, Inc., South San Francisco, CA., Hötzel K; Department of Pathology, Genentech, Inc., South San Francisco, CA., Gogineni A; Department of Biomedical Imaging, Genentech, Inc., South San Francisco, CA., Lee WP; Department of Translational Immunology, Genentech, Inc., South San Francisco, CA., Suto E; Department of Translational Immunology, Genentech, Inc., South San Francisco, CA., Wu X; Department of Translational Immunology, Genentech, Inc., South San Francisco, CA., Liu J; Department of Translational Immunology, Genentech, Inc., South San Francisco, CA., Zhang J; Department of Translational Immunology, Genentech, Inc., South San Francisco, CA., Gandham V; Department of Biomedical Imaging, Genentech, Inc., South San Francisco, CA., Wang J; Department of Biochemical and Cellular Pharmacology, Genentech, Inc., South San Francisco, CA., Payandeh J; Department of Structural Biology, Genentech, Inc., South San Francisco, CA., Ciferri C; Department of Structural Biology, Genentech, Inc., South San Francisco, CA., Estevez A; Department of Structural Biology, Genentech, Inc., South San Francisco, CA., Arthur CP; Department of Structural Biology, Genentech, Inc., South San Francisco, CA., Kortmann J; Department of Immunology Discovery, Genentech, Inc., South San Francisco, CA., Wong RL; Department of Immunology Discovery, Genentech, Inc., South San Francisco, CA., Heredia JE; Department of Immunology Discovery, Genentech, Inc., South San Francisco, CA., Doerr J; Department of Molecular Biology, Genentech, Inc., South San Francisco, CA., Jung M; Department of OMNI Bioinformatics, Genentech, Inc., South San Francisco, CA., Vander Heiden JA; Department of OMNI Bioinformatics, Genentech, Inc., South San Francisco, CA., Roose-Girma M; Department of Molecular Biology, Genentech, Inc., South San Francisco, CA., Tam L; Department of Molecular Biology, Genentech, Inc., South San Francisco, CA., Barck KH; Department of Biomedical Imaging, Genentech, Inc., South San Francisco, CA., Carano RAD; Department of Biomedical Imaging, Genentech, Inc., South San Francisco, CA., Ding HT; Department of Clinical Pharmacology, Genentech, Inc., South San Francisco, CA., Brillantes B; Department of Biomolecular Resources, Genentech, Inc., South San Francisco, CA., Tam C; Department of Biomolecular Resources, Genentech, Inc., South San Francisco, CA., Yang X; Department of Product Development Biometric Biostatistics, Genentech, Inc., South San Francisco, CA., Gao SS; Department of Clinical Imaging, Genentech, Inc., South San Francisco, CA., Ly JQ; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, CA., Liu L; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, CA., Chen L; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, CA., Liederer BM; Department of Drug Metabolism and Pharmacokinetics, Genentech, Inc., South San Francisco, CA., Lin JH; Department of Early Clinical Development, Genentech, Inc., South San Francisco, CA., Magnuson S; Department of Discovery Chemistry, Genentech, Inc., South San Francisco, CA., Chen J; Department of Biochemical and Cellular Pharmacology, Genentech, Inc., South San Francisco, CA., Hackos DH; Department of Neuroscience, Genentech, Inc., South San Francisco, CA., Elstrott J; Department of Biomedical Imaging, Genentech, Inc., South San Francisco, CA., Rohou A; Department of Structural Biology, Genentech, Inc., South San Francisco, CA., Safina BS; Department of Discovery Chemistry, Genentech, Inc., South San Francisco, CA., Volgraf M; Department of Discovery Chemistry, Genentech, Inc., South San Francisco, CA., Bauer RN; Department of OMNI-Biomarker Development, Genentech, Inc., South San Francisco, CA., Riol-Blanco L; Department of Immunology Discovery, Genentech, Inc., South San Francisco, CA.
Publikováno v: The Journal of experimental medicine [J Exp Med] 2021 Apr 05; Vol. 218 (4).
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5
Akademický článek
Curse or Cure? A Perspective on the Developability of Aldehydes as Active Pharmaceutical Ingredients.
Autor: Gampe C; Genentech, 1 DNA Way, South San Francisco, 94080 California, United States., Verma VA; Genentech, 1 DNA Way, South San Francisco, 94080 California, United States.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2020 Dec 10; Vol. 63 (23), pp. 14357-14381. Date of Electronic Publication: 2020 Sep 29.
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6
Akademický článek
Lipid metabolism reprogramming in endometrial cancer: biological functions and therapeutic implications.
Autor: Wang, Xiangyu1 (AUTHOR), Li, Yinuo1 (AUTHOR), Hou, Xin1 (AUTHOR), Li, Jingfang1 (AUTHOR), Ma, Xiangyi1 (AUTHOR) xyma@tjh.tjmu.edu.cn
Publikováno v: Cell Communication & Signaling. 9/10/2024, Vol. 22 Issue 1, p1-19. 19p.
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8
Akademický článek
Exploration of Pyrrolobenzodiazepine (PBD)-Dimers Containing Disulfide-Based Prodrugs as Payloads for Antibody-Drug Conjugates.
Autor: Pei Z; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Chen C; WuXi Biologics, 288 Fute Zhong Road , Waigaoqiao Free Trade Zone, Shanghai 200131 , China., Chen J; Wuxi Apptec , 288 Fute Zhong Road , Waigaoqiao Free Trade Zone, Shanghai 200131 , China., Cruz-Chuh JD; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Delarosa R; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Deng Y; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Fourie-O'Donohue A; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Figueroa I; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Guo J; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Jin W; WuXi Biologics, 288 Fute Zhong Road , Waigaoqiao Free Trade Zone, Shanghai 200131 , China., Khojasteh SC; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Kozak KR; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Latifi B; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Lee J; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Li G; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Lin E; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Liu L; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Lu J; WuXi Biologics, 288 Fute Zhong Road , Waigaoqiao Free Trade Zone, Shanghai 200131 , China., Martin S; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Ng C; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Nguyen T; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Ohri R; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Lewis Phillips G; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Pillow TH; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Rowntree RK; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Stagg NJ; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Stokoe D; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Ulufatu S; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Verma VA; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Wai J; Wuxi Apptec , 288 Fute Zhong Road , Waigaoqiao Free Trade Zone, Shanghai 200131 , China., Wang J; Wuxi Apptec , 288 Fute Zhong Road , Waigaoqiao Free Trade Zone, Shanghai 200131 , China., Xu K; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Xu Z; Wuxi Apptec , 288 Fute Zhong Road , Waigaoqiao Free Trade Zone, Shanghai 200131 , China., Yao H; Wuxi Apptec , 288 Fute Zhong Road , Waigaoqiao Free Trade Zone, Shanghai 200131 , China., Yu SF; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Zhang D; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States., Dragovich PS; Genentech Inc. , 1 DNA Way , South San Francisco , California 94080 , United States.
Publikováno v: Molecular pharmaceutics [Mol Pharm] 2018 Sep 04; Vol. 15 (9), pp. 3979-3996. Date of Electronic Publication: 2018 Aug 06.
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9
Akademický článek
Discovery of a Potent (4 R,5 S)-4-Fluoro-5-methylproline Sulfonamide Transient Receptor Potential Ankyrin 1 Antagonist and Its Methylene Phosphate Prodrug Guided by Molecular Modeling.
Autor: Chen H, Volgraf M, Do S, Kolesnikov A, Shore DG, Verma VA, Villemure E, Wang L, Chen Y; Pharmaron-Beijing Co. Ltd. , 6 Taihe Road, BDA , Beijing 100176 , P. R. China., Hu B; Pharmaron-Beijing Co. Ltd. , 6 Taihe Road, BDA , Beijing 100176 , P. R. China., Lu AJ; Pharmaron-Beijing Co. Ltd. , 6 Taihe Road, BDA , Beijing 100176 , P. R. China., Wu G; Pharmaron-Beijing Co. Ltd. , 6 Taihe Road, BDA , Beijing 100176 , P. R. China., Xu X; Pharmaron-Beijing Co. Ltd. , 6 Taihe Road, BDA , Beijing 100176 , P. R. China., Yuen PW; Pharmaron-Beijing Co. Ltd. , 6 Taihe Road, BDA , Beijing 100176 , P. R. China., Zhang Y; Pharmaron-Beijing Co. Ltd. , 6 Taihe Road, BDA , Beijing 100176 , P. R. China., Erickson SD; Small Molecule Research, Pharmaceutical Research and Early Drug Development , Hoffmann-La Roche Inc. , 340 Kingsland Street , Nutley , New Jersey 07110 , United States., Dahl M; Small Molecule Research, Pharmaceutical Research and Early Drug Development , Hoffmann-La Roche Inc. , 340 Kingsland Street , Nutley , New Jersey 07110 , United States., Brotherton-Pleiss C; Small Molecule Research, Pharmaceutical Research and Early Drug Development , Hoffmann-La Roche Inc. , 340 Kingsland Street , Nutley , New Jersey 07110 , United States., Tay S, Ly JQ, Murray LJ, Chen J, Amm D; Ion Channels Group, Evotec AG , Manfred Eigen Campus, Essener Bogen 7 , 22419 Hamburg , Germany., Lange W; Ion Channels Group, Evotec AG , Manfred Eigen Campus, Essener Bogen 7 , 22419 Hamburg , Germany., Hackos DH, Reese RM, Shields SD, Lyssikatos JP, Safina BS, Estrada AA
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2018 Apr 26; Vol. 61 (8), pp. 3641-3659. Date of Electronic Publication: 2018 Apr 12.
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10
Akademický článek
Probing the allosteric NBD-TMD crosstalk in the ABC transporter MsbA by solid-state NMR.
Autor: Novischi, S. Y. Phoebe1 (AUTHOR), Karoly-Lakatos, Andrea1 (AUTHOR), Chok, Kerby1 (AUTHOR), Bonifer, Christian1 (AUTHOR), Becker-Baldus, Johanna1 (AUTHOR), Glaubitz, Clemens1 (AUTHOR) glaubitz@em.uni-frankfurt.de
Publikováno v: Communications Biology. 1/5/2024, Vol. 7 Issue 1, p1-11. 11p.
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