Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Verl Siththanandan"'
Autor:
Nikolaus R. Wagner, Ashis Sinha, Verl Siththanandan, Angelica M. Kowalchuk, Jessica L. MacDonald, Suzanne Tharin
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
The evolutionary emergence of the corticospinal tract and corpus callosum are thought to underpin the expansion of complex motor and cognitive abilities in mammals. Molecular mechanisms regulating development of the neurons whose axons comprise these
Externí odkaz:
https://doaj.org/article/79d7b588615e43ecb088e961edbc7f99
Autor:
Rong Liu, Neil Billington, Yi Yang, Charles Bond, Amy Hong, Verl Siththanandan, Yasuharu Takagi, James R. Sellers
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Myosin-7a is found in actin bundles, microvilli and stereocilia, and plays conserved roles in hearing and vision. Here the authors identify M7BP, a myosin-7a binding protein that activates and dimerizes myosin-7a, enabling cargo transport and assembl
Externí odkaz:
https://doaj.org/article/82ee430ef28b4669aae273c5e81f0e66
Autor:
Amy Hong, Rong Liu, Charles Bond, Yasuharu Takagi, Yi Yang, Neil Billington, James R. Sellers, Verl Siththanandan
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Myosin-7a, despite being monomeric in isolation, plays roles in organizing actin-based cell protrusions such as filopodia, microvilli and stereocilia, as well as transporting cargoes within them. Here, we identify a binding protein for Drosophila myo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8a285273ce1ecc1a97d145b19e61f2b
https://pubmed.ncbi.nlm.nih.gov/33495456
https://pubmed.ncbi.nlm.nih.gov/33495456
Autor:
James R. Sellers, Charles Bond, Amy Hong, Rong Liu, Yi Yang, Verl Siththanandan, Neil Billington, Yasuharu Takagi
Publikováno v:
Biophysical Journal. 118:433a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8688312cade0a6a04cec9d24c318a068
https://doi.org/10.1016/j.bpj.2019.11.2434
https://doi.org/10.1016/j.bpj.2019.11.2434
Autor:
Xufeng Wu, Verl Siththanandan, Yasuharu Takagi, Neil Billington, Fang Zhang, Yi Yang, James R. Sellers, Amy Hong, Rong Liu
Publikováno v:
Biophysical Journal. 114:210a-211a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58e7e089c869bb8ab4ea4b0a66f96be0
https://doi.org/10.1016/j.bpj.2017.11.1179
https://doi.org/10.1016/j.bpj.2017.11.1179
Autor:
James R. Sellers, Verl Siththanandan
Publikováno v:
Biochemical Society Transactions. 39:1136-1141
The myosin superfamily is diverse in its structure, kinetic mechanisms and cellular function. The enzymatic activities of most myosins are regulated by some means such as Ca2+ ion binding, phosphorylation or binding of other proteins. In the present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d7a5ef2d616211144a2a6d090ebf94d
https://doi.org/10.1042/bst0391136
https://doi.org/10.1042/bst0391136
Autor:
Michael A. Ferenczi, Gabor Hild, John E. T. Corrie, Martin R. Webb, Timothy G. West, Verl Siththanandan
Publikováno v:
Biophysical Journal. 96(8):3281-3294
A phosphorylated, single cysteine mutant of nucleoside diphosphate kinase, labeled with N-[2-(iodoacetamido)ethyl]-7-diethylaminocoumarin-3-carboxamide (P approximately NDPK-IDCC), was used as a fluorescence probe for time-resolved measurement of cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3ffde87c6d29adc68dba113355d9443
Autor:
Yi Yang, Matt L. Walker, Michael Chen, James R. Sellers, Peter J. Knight, Verl Siththanandan, Thomas G. Baboolal, Michelle Peckham
Full-length Drosophila myosin 7a (myosin 7a-FL) has a complex tail containing a short predicted coiled coil followed by a MyTH4-FERM domain, an SH3 domain, and a C-terminal MyTH4-FERM domain. Myosin 7a-FL expressed in Sf9 cells is monomeric despite t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a489d58e2313c6ee940338969c222262
https://europepmc.org/articles/PMC2649957/
https://europepmc.org/articles/PMC2649957/
Autor:
Sergey Y. Bershitsky, W.I. Helsby, Verl Siththanandan, Pierre Panine, Andrey K. Tsaturyan, Natalia A. Koubassova, Manfred Roessle, Theyencheri Narayanan, Michael A. Ferenczi
Publikováno v:
Structure (London, England : 1993). 13(1)
Summary Muscle force results from the interaction of the globular heads of myosin-II with actin filaments. We studied the structure-function relationship in the myosin motor in contracting muscle fibers by using temperature jumps or length steps comb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8023c85f653fcba491801de6b348fda5
https://pubmed.ncbi.nlm.nih.gov/15642268
https://pubmed.ncbi.nlm.nih.gov/15642268
Autor:
Thomas G. Baboolal, Michelle Peckham, Yi Yang, James R. Sellers, Verl Siththanandan, Matt L. Walker, Peter J. Knight
Publikováno v:
Biophysical Journal. 96(3):3a-4a
Drosophila myosin-7a is a single-headed myosin with a tail containing two MyTH4-FERM domains separated by an SH3 domain. Myosin-7a is often found in regions of high actin density and mutations in human myosin-7a result in deafness and blindness. We h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f1929455ebd04f811cd99ad58da61a