Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Verian Bader"'
Autor:
Michael Hermann Wißing, Toni Luise Meister, Maximilian Klaus Nocke, André Gömer, Mejrema Masovic, Leonard Knegendorf, Yannick Brüggemann, Verian Bader, Anindya Siddharta, Claus-Thomas Bock, Alexander Ploss, Scott P. Kenney, Konstanze F. Winklhofer, Patrick Behrendt, Heiner Wedemeyer, Eike Steinmann, Daniel Todt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Hepatitis E virus (HEV) is a long-neglected RNA virus and the major causative agent of acute viral hepatitis in humans. Recent data suggest that HEV has a very heterogeneous hypervariable region (HVR), which can tolerate major genomic rearra
Externí odkaz:
https://doaj.org/article/36a2243de9ad4d3885e1b54753f3ea25
Autor:
Nikolas Furthmann, Verian Bader, Lena Angersbach, Alina Blusch, Simran Goel, Ana Sánchez-Vicente, Laura J. Krause, Sarah A. Chaban, Prerna Grover, Victoria A. Trinkaus, Eva M. van Well, Maximilian Jaugstetter, Kristina Tschulik, Rune Busk Damgaard, Carsten Saft, Gisa Ellrichmann, Ralf Gold, Arend Koch, Benjamin Englert, Ana Westenberger, Christine Klein, Lisa Jungbluth, Carsten Sachse, Christian Behrends, Markus Glatzel, F. Ulrich Hartl, Ken Nakamura, Chadwick W. Christine, Eric J. Huang, Jörg Tatzelt, Konstanze F. Winklhofer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-24 (2023)
Abstract NEMO is a ubiquitin-binding protein which regulates canonical NF-κB pathway activation in innate immune signaling, cell death regulation and host-pathogen interactions. Here we identify an NF-κB-independent function of NEMO in proteostasis
Externí odkaz:
https://doaj.org/article/254c39b4dc224a428f4f65c841b52060
Autor:
Hilal Cihankaya, Verian Bader, Konstanze F. Winklhofer, Matthias Vorgerd, Johann Matschke, Sarah Stahlke, Carsten Theiss, Veronika Matschke
Publikováno v:
Cells, Vol 13, Iss 12, p 995 (2024)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by motor neuron degeneration in the central nervous system. Recent research has increasingly linked the activation of nucleotide oligomerization domain-like recept
Externí odkaz:
https://doaj.org/article/64776c81889148ebbfca908b0baa0155
Autor:
Maya Junghans, Felix John, Hilal Cihankaya, Daniel Schliebs, Konstanze F. Winklhofer, Verian Bader, Johann Matschke, Carsten Theiss, Veronika Matschke
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Background: Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disease characterized by the loss of motor neurons in cerebral cortex, brainstem and spinal cord. Numerous studies have demonstrated signs of oxidative stress in postmo
Externí odkaz:
https://doaj.org/article/5abadaa444884d188c726ea89d05ffb0
Autor:
Cornelius Mueller-Buehl, Jacqueline Reinhard, Lars Roll, Verian Bader, Konstanze F. Winklhofer, Andreas Faissner
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Fast-spiking parvalbumin interneurons are critical for the function of mature cortical inhibitory circuits. Most of these neurons are enwrapped by a specialized extracellular matrix (ECM) structure called perineuronal net (PNN), which can regulate th
Externí odkaz:
https://doaj.org/article/212563a364134ad592f6e26253856357
Autor:
David Marks, Natalie Heinen, Lisa Bachmann, Sophia Meermeyer, Michelle Werner, Lucia Gallego, Peter Hemmerich, Verian Bader, Konstanze F. Winklhofer, Elisabeth Schröder, Shirley K. Knauer, Thorsten Müller
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-16 (2021)
Abstract The amyloid precursor protein (APP) is a type I transmembrane protein with unknown physiological function but potential impact in neurodegeneration. The current study demonstrates that APP signals to the nucleus causing the generation of agg
Externí odkaz:
https://doaj.org/article/3bde9ac885af4675b505ae599942c36d
Autor:
Sebastian Jung, Verian Bader, Ana Natriashvili, Hans-Georg Koch, Konstanze F. Winklhofer, Jörg Tatzelt
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract OmpC and OmpF are among the most abundant outer membrane proteins in E. coli and serve as hydrophilic channels to mediate uptake of small molecules including antibiotics. Influx selectivity is controlled by the so-called constriction zone or
Externí odkaz:
https://doaj.org/article/85496819d379446e91f9fae7cfa50b28
Autor:
Markus Teucher, Hui Zhang, Verian Bader, Konstanze F. Winklhofer, Ana J. García-Sáez, Andrzej Rajca, Stephanie Bleicken, Enrica Bordignon
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Abstract Bax is a Bcl-2 protein crucial for apoptosis initiation and execution, whose active conformation is only partially understood. Dipolar EPR spectroscopy has proven to be a valuable tool to determine coarse-grained models of membrane-embedded
Externí odkaz:
https://doaj.org/article/daf6f5f4ac01421a922c80047164d90d
Autor:
Agnes Ulfig, Verian Bader, Marharyta Varatnitskaya, Natalie Lupilov, Konstanze F. Winklhofer, Lars I. Leichert
Publikováno v:
Redox Biology, Vol 43, Iss , Pp 101981- (2021)
Macrophages are innate immune cells that internalize and present exogenous antigens to T cells via MHC class II proteins. They operate at sites of infection in a highly inflammatory environment, generated in part by reactive oxygen species, in partic
Externí odkaz:
https://doaj.org/article/3c26e4bd688b45ada13a8e83e8aaae1d
Autor:
Kaibo Xie, Marharyta Varatnitskaya, Abdelouahid Maghnouj, Verian Bader, Konstanze F. Winklhofer, Stephan Hahn, Lars I. Leichert
Publikováno v:
Redox Biology, Vol 28, Iss , Pp - (2020)
Neutrophils produce a cocktail of oxidative species during the so-called oxidative burst to attack phagocytized bacteria. However, little is known about the neutrophils' redox homeostasis during the oxidative burst and there is currently no consensus
Externí odkaz:
https://doaj.org/article/9f4c46784d9348f28c75f90f9d8ce9d6