Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Verge de Los Aires A"'
Autor:
James J. Gilchrist, Seiko Makino, Vivek Naranbhai, Piyush K. Sharma, Surya Koturan, Orion Tong, Chelsea A. Taylor, Robert A. Watson, Alba Verge de los Aires, Rosalin Cooper, Evelyn Lau, Sara Danielli, Dan Hameiri-Bowen, Wanseon Lee, Esther Ng, Justin Whalley, Julian C. Knight, Benjamin P. Fairfax
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Natural Killer cells are key mediators of anti-tumour immunosurveillance and anti-viral immunity. Here, the authors map regulatory genetic variation in primary Natural Killer cells, providing new insights into their role in human health and disease.
Externí odkaz:
https://doaj.org/article/cbbc9c0a99e94646b648b74ad72ecb2a
Autor:
Bénédict Fallet, Yi Hao, Marianna Florova, Karen Cornille, Alba Verge de los Aires, Giulia Girelli Zubani, Yusuf I. Ertuna, Victor Greiff, Ulrike Menzel, Karim Hammad, Doron Merkler, Sai T. Reddy, Jean-Claude Weill, Claude-Agnès Reynaud, Daniel D. Pinschewer
Publikováno v:
Cell Reports, Vol 30, Iss 4, Pp 1013-1026.e7 (2020)
Summary: Persistent viral infections subvert key elements of adaptive immunity. To compare germinal center (GC) B cell responses in chronic and acute lymphocytic choriomeningitis virus infection, we exploit activation-induced deaminase (AID) fate-rep
Externí odkaz:
https://doaj.org/article/1e1d8fe3acfc47169da56f38415abc28
Autor:
Robert A. Watson, Chelsea A. Taylor, Orion Tong, Rosalin Cooper, Elsita Jungkurth, Piyush Kumar Sharma, Bethan Storey, Weiyu Ye, Bo Sun, Alba Verge de los Aires, Flavia Matos Santo, Isar Nassiri, James J. Gilchrist, Eleni Ieremia, Mark R. Middleton, Benjamin P. Fairfax
Immune checkpoint blockade (ICB) has markedly improved outcomes across a range of tumours, including metastatic melanoma (MM). However, peripheral biomarkers of response remain lacking and underlying mechanisms of action incompletely described. A num
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb06cfffc46000bf093ea5dec1de454e
https://doi.org/10.1101/2023.02.11.528080
https://doi.org/10.1101/2023.02.11.528080
Autor:
Weller, Sandra, Sterlin, Delphine, Fadeev, Tatiana, Coignard, Eva, Verge de los Aires, Alba, Goetz, Clara, Fritzen, Rémi, Bahuaud, Mathilde, Batteux, Frederic, Gorochov, Guy, Weill, Jean-Claude, Reynaud, Claude-Agnès
Publikováno v:
Science Immunology. 8
Marginal zone (MZ) B cells are one of the main actors of T-independent (TI) responses in mice. To identify the B cell subset(s) involved in such responses in humans, we vaccinated healthy individuals with Pneumovax, a model TI vaccine. By high-throug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eb70e8434ebc8190f5e6df3e33fc34a
https://doi.org/10.1126/sciimmunol.ade1413
https://doi.org/10.1126/sciimmunol.ade1413
Autor:
Benjamin Fairfax, Chelsea Taylor, Robert Watson, Orion Tong, Weiyu Ye, Isar Nassiri, James Gilchrist, Alba Verge de los Aires, Piyush Sharma, Surya Koturan, Rosalin Cooper, Victoria Woodcock, Elsita Jungkurth, Brian Shine, Nicholas Coupe, Miranda Payne, Vivek Naranbhai, Stefan Groha, Paul Emery, Kulveer Mankia, Matthew Freedman, Toni Choueiri, M Middleton, Alexander Gusev
Although treatment with immune checkpoint blockade (ICB) has transformed outcomes for patients with melanoma (1, 2), it frequently triggers immune related adverse events (irAEs), causing serious morbidity and presenting a major hurdle to immuno-oncol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::860696c0efeb58e147c6b78c5707d2a0
https://doi.org/10.21203/rs.3.rs-1531341/v1
https://doi.org/10.21203/rs.3.rs-1531341/v1
Autor:
Chelsea A. Taylor, Robert A. Watson, Orion Tong, Weiyu Ye, Isar Nassiri, James J. Gilchrist, Alba Verge de los Aires, Piyush Kumar Sharma, Surya Koturan, Rosalin A. Cooper, Victoria K. Woodcock, Elsita Jungkurth, Brian Shine, Nicholas Coupe, Miranda J. Payne, David N. Church, Vivek Naranbhai, Stefan Groha, Paul Emery, Kulveer Mankia, Matthew L. Freedman, Toni K. Choueiri, Mark R. Middleton, Alexander Gusev, Benjamin P. Fairfax
Publikováno v:
Nature medicine. 28(12)
Treatment with immune checkpoint blockade (ICB) frequently triggers immune-related adverse events (irAEs), causing considerable morbidity. In 214 patients receiving ICB for melanoma, we observed increased severe irAE risk in minor allele carriers of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c10b9965e7948bb4b13ce5c06561db93
https://pubmed.ncbi.nlm.nih.gov/36526722
https://pubmed.ncbi.nlm.nih.gov/36526722
Autor:
R.A. Watson, C.A. Taylor, O. Tong, R. Cooper, I. Nassiri, E. Jungkurth, P.K. Sharma, A. Verge de los Aires, E. Ieremia, M.R. Middleton, B.P. Fairfax
Publikováno v:
Annals of Oncology. 33:S878-S879
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e21b43b8b607a39464fb8e881eaea3dc
https://doi.org/10.1016/j.annonc.2022.07.860
https://doi.org/10.1016/j.annonc.2022.07.860
Autor:
Robert A, Watson, Orion, Tong, Rosalin, Cooper, Chelsea A, Taylor, Piyush K, Sharma, Alba Verge, de Los Aires, Elise A, Mahé, Hélène, Ruffieux, Isar, Nassiri, Mark R, Middleton, Benjamin P, Fairfax
Publikováno v:
Sci Immunol
The antitumor action of immune checkpoint blockade (ICB) is primarily mediated by CD8(+) T cells. How sensitivity to ICB varies across CD8(+) T cell subsets and clonotypes and the relationship of these with clinical outcome is unclear. To explore thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d5c7e12fb586a480cd2b0bb5a629660
https://pubmed.ncbi.nlm.nih.gov/34597125
https://pubmed.ncbi.nlm.nih.gov/34597125
Autor:
Isar Nassiri, Fairfax Bp, Rosalin Cooper, A. Verge de Los Aires, Orion Tong, Sharma Pk, Mahé Ea, Watson Ra, Middleton Mr, Taylor Ca, Hélène Ruffieux
Immune checkpoint blockers (ICB) exert their anti-cancer effects via CD8+ T cells, although how responses vary over sub-populations and across clones is incompletely understood. We performed single-cell RNA-sequencing of CD8+ T cells and their recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7d124c4fec3096d597cc6f27165fcec
https://doi.org/10.1101/2020.11.15.383786
https://doi.org/10.1101/2020.11.15.383786
Autor:
Isar Nassiri, Chelsea A Taylor, P. Kumar Sharma, Rosalin Cooper, Benjamin P. Fairfax, A. Verge de los Aires, E Mahe, R.A. Watson, S Danielli, Orion Tong
Publikováno v:
Annals of Oncology. 32:S1211
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4fc4d59e2b2a79ace8066599928e16e
https://doi.org/10.1016/j.annonc.2021.08.1706
https://doi.org/10.1016/j.annonc.2021.08.1706