Single cell dynamics of tumor specificity vs bystander activity in CD8 ⁺ T cells define the diverse immune landscapes in colorectal cancer.

Autor: Borràs DM; Cell Stress and Immunity (CSI) Lab, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Verbandt S; Digestive Oncology, Department of Oncology, KU Leuven, Leuven, Belgium., Ausserhofer M; Universität Innsbruck, Department of Molecular Biology, Digital Science Center (DiSC), Innsbruck, Austria., Sturm G; Biocenter, Institute of Bioinformatics, Medical University of Innsbruck, Innsbruck, Austria., Lim J; Department of Health Sciences and Technology, Samsung Advanced Institute for Health Science and Technology, Sungkyunkwan University, Seoul, Republic of Korea.; Samsung Genome Institute, Samsung Medical Center, Sungkyunkwan University, Seoul, Republic of Korea., Verge GA; Cell Stress and Immunity (CSI) Lab, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Vanmeerbeek I; Cell Stress and Immunity (CSI) Lab, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Laureano RS; Cell Stress and Immunity (CSI) Lab, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Govaerts J; Cell Stress and Immunity (CSI) Lab, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Sprooten J; Cell Stress and Immunity (CSI) Lab, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Hong Y; Digestive Oncology, Department of Oncology, KU Leuven, Leuven, Belgium., Wall R; Digestive Oncology, Department of Oncology, KU Leuven, Leuven, Belgium., De Hertogh G; Department of Pathology, University Hospitals Leuven, Leuven, Belgium., Sagaert X; Department of Pathology, University Hospitals Leuven, Leuven, Belgium., Bislenghi G; Department of Abdominal Surgery, University Hospitals Leuven, Leuven, Belgium., D'Hoore A; Department of Abdominal Surgery, University Hospitals Leuven, Leuven, Belgium., Wolthuis A; Department of Abdominal Surgery, University Hospitals Leuven, Leuven, Belgium., Finotello F; Universität Innsbruck, Department of Molecular Biology, Digital Science Center (DiSC), Innsbruck, Austria., Park WY; Department of Health Sciences and Technology, Samsung Advanced Institute for Health Science and Technology, Sungkyunkwan University, Seoul, Republic of Korea.; Samsung Genome Institute, Samsung Medical Center, Sungkyunkwan University, Seoul, Republic of Korea., Naulaerts S; Cell Stress and Immunity (CSI) Lab, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Tejpar S; Digestive Oncology, Department of Oncology, KU Leuven, Leuven, Belgium. sabine.tejpar@kuleuven.be., Garg AD; Cell Stress and Immunity (CSI) Lab, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium. abhishek.garg@kuleuven.be.

Publikováno v: Cell discovery [Cell Discov] 2023 Nov 15; Vol. 9 (1), pp. 114. Date of Electronic Publication: 2023 Nov 15.