Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Verena Thalhammer"'
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140076 (2015)
The packaging of DNA into nucleosomes and the organisation into higher order structures of chromatin limits the access of sequence specific DNA binding factors to DNA. In cells, DNA methylation is preferentially occuring in the linker region of nucle
Externí odkaz:
https://doaj.org/article/08840385232749ea95dcaf3cb2d1b169
Autor:
Beat W. Schäfer, Ewa Koscielniak, Bernd Blank, Paolo Nanni, Peter Bode, Marco Wachtel, Maria E. Gierisch, Dominik Laubscher, Regina Hecker, David Herrero-Martin, Laura A. Lopez-Garcia, Verena Thalhammer
Supplementary Table S3. PAX3-FOXO1 phospho-peptides identified by mass spectrometry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d49dfaa39017fb8bb19f4f8521f00cf
https://doi.org/10.1158/0008-5472.22406300
https://doi.org/10.1158/0008-5472.22406300
Autor:
Beat W. Schäfer, Ewa Koscielniak, Bernd Blank, Paolo Nanni, Peter Bode, Marco Wachtel, Maria E. Gierisch, Dominik Laubscher, Regina Hecker, David Herrero-Martin, Laura A. Lopez-Garcia, Verena Thalhammer
Pediatric tumors harbor very low numbers of somatic mutations and therefore offer few targets to improve therapeutic management with targeted drugs. In particular, outcomes remain dismal for patients with metastatic alveolar rhabdomyosarcoma (aRMS),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8db77c9439699b7ea833a8851f179e2d
https://doi.org/10.1158/0008-5472.c.6507038
https://doi.org/10.1158/0008-5472.c.6507038
Autor:
Beat W. Schäfer, Ewa Koscielniak, Bernd Blank, Paolo Nanni, Peter Bode, Marco Wachtel, Maria E. Gierisch, Dominik Laubscher, Regina Hecker, David Herrero-Martin, Laura A. Lopez-Garcia, Verena Thalhammer
Supplementary Figure Legends. Legend for Supplementary Figures S1-S7.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd2f04dc5f923c21648c84f408f6dcac
https://doi.org/10.1158/0008-5472.22406315.v1
https://doi.org/10.1158/0008-5472.22406315.v1
Autor:
Beat W. Schäfer, Ewa Koscielniak, Bernd Blank, Paolo Nanni, Peter Bode, Marco Wachtel, Maria E. Gierisch, Dominik Laubscher, Regina Hecker, David Herrero-Martin, Laura A. Lopez-Garcia, Verena Thalhammer
Supplementary Materials and Methods. Description of additional methods and procedures used in the study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589222c131d0d9ec64e0f8537183cdbb
https://doi.org/10.1158/0008-5472.22406309.v1
https://doi.org/10.1158/0008-5472.22406309.v1
Autor:
Regina Hecker, Ewa Koscielniak, Peter K. Bode, Maria E. Gierisch, David Herrero-Martin, Bernd Blank, Laura A. Lopez-Garcia, Marco Wachtel, Verena Thalhammer, Dominik Laubscher, Paolo Nanni, Beat W. Schäfer
Publikováno v:
Cancer research
Pediatric tumors harbor very low numbers of somatic mutations and therefore offer few targets to improve therapeutic management with targeted drugs. In particular, outcomes remain dismal for patients with metastatic alveolar rhabdomyosarcoma (aRMS),
Publikováno v:
Molecular Human Reproduction. 14:431-444
Whether exogenous factors influenced the level of mitochondrial polarity (DeltaPsim) in the subplasmalemmal cytoplasm of the oocyte was investigated with denuded and cumulus-enclosed human and mouse oocytes between the germinal vesicle and metaphase
Autor:
Kathya Pretre, Susanne Oesch, Verena Thalhammer, Aleksandar Boro, Felix Niggli, Beat W. Schäfer, Marco Wachtel, Florian Rechfeld
Ewing's sarcoma family of tumors (EFT) is characterized by the presence of chromosomal translocations leading to the expression of oncogenic transcription factors such as, in the majority of cases, EWS/FLI1. Because of its key role in Ewing's sarcoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c70e1cce0bf7372112d8c849d4bd82
https://www.zora.uzh.ch/id/eprint/70710/
https://www.zora.uzh.ch/id/eprint/70710/
Autor:
Marco Wachtel, Regina Hecker, Beat W. Schäfer, Dominik Laubscher, Verena Thalhammer, Peter K. Bode, Laura A. Lopez-Garcia, David Herrero-Martin
Publikováno v:
Cancer Research. 74:3966-3966
Oncogenic addiction provides an opportunity to develop new treatment options, especially for childhood cancers. Pediatric tumors contain a lower number of oncogenic mutations compared to most adult cancers, suggesting stronger dependency on individua
Publikováno v:
Cancer Research. 72:271-271
Oncogenic transcription factors are the second most frequently mutated class of proteins. They represent ideal therapeutic targets because oncogene addiction is common to a broad spectrum of tumors and their inhibition may help to develop further alt