Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Verena Schuette"'
Publikováno v:
Biochemical and Biophysical Research Communications. 629:171-175
Melanoma differentiation-associated gene 5 (MDA5) is an essential viral double-stranded RNA sensor to trigger antiviral immune responses, including type I interferon (IFN) induction. Aberrant activation of this viral sensor is known to cause autoimmu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c6764188662a70667cec12b599926f9
http://hdl.handle.net/2433/282775
http://hdl.handle.net/2433/282775
Autor:
Sven Burgdorf, Verena Schuette
Publikováno v:
Current opinion in immunology. 26
The efficiency of antigen cross-presentation, which is the presentation of extracellular antigens on MHC I molecules, critically depends on the stability of the internalized antigens. Since rapid degradation within the lysosomal compartment impairs c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::439e2edc7f499eed572d9908282ec5b4
https://pubmed.ncbi.nlm.nih.gov/24556402
https://pubmed.ncbi.nlm.nih.gov/24556402
Autor:
Verena Schuette, Christian Kurts, Katharina Hochheiser, Percy A. Knolle, Veronika Lukacs-Kornek, Sven Burgdorf, Verena Semmling
Publikováno v:
Proceedings of the National Academy of Sciences. 107
Cross-presentation allows dendritic cells (DCs) to load antigenic peptides on MHC-I molecules, which is important for activating cytotoxic T cells (CTL) that combat tumors and viruses. We recently showed that, under steady-state conditions, antigens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20151ffe2606a0c5fe9a7ac14762ebba
https://doi.org/10.1073/pnas.1000598107
https://doi.org/10.1073/pnas.1000598107
Autor:
Martina Berg, Hansjörg Schild, Michaela Kern, Linda Diehl, Jan P. Böttcher, Verena Schuette, D Stabenow, Sven Burgdorf, Christian Kurts, Anna Schurich, Andreas Limmer, Percy A. Knolle
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 184(8)
Cross-presentation of soluble Ag on MHC class I molecules to naive CD8 T cells by liver sinusoidal endothelial cells (LSECs) leads to induction of T cell tolerance that requires interaction between coinhibitory B7-H1 on LSECs and programmed cell deat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::568ca103cb69349efa9bc2dcfb63acb0
https://pubmed.ncbi.nlm.nih.gov/20425916
https://pubmed.ncbi.nlm.nih.gov/20425916