Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Verena Schlaphoff"'
Autor:
Richard Taubert, Matthias Hardtke-Wolenski, Fatih Noyan, Claudine Lalanne, Danny Jonigk, Jerome Schlue, Till Krech, Ralf Lichtinghagen, Christine S Falk, Verena Schlaphoff, Heike Bantel, Luigi Muratori, Michael P Manns, Elmar Jaeckel
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179074 (2017)
Autoimmune hepatitis (AIH) is a chronic hepatitis with an increasing incidence. The majority of patients require life-long immunosuppression and incomplete treatment response is associated with a disease progression. An abnormal iron homeostasis or h
Externí odkaz:
https://doaj.org/article/ebbf465973454f569aff82c17f17f705
Autor:
Isabel Veloso Alves Pereira, Bettina Buchmann, Lisa Sandmann, Kathrin Sprinzl, Verena Schlaphoff, Katinka Döhner, Florian Vondran, Christoph Sarrazin, Michael P Manns, Cláudia Pinto Marques Souza de Oliveira, Beate Sodeik, Sandra Ciesek, Thomas von Hahn
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117152 (2015)
The sodium-taurocholate cotransporting polypeptide (NTCP) is both a key bile acid (BA) transporter mediating uptake of BA into hepatocytes and an essential receptor for hepatitis B virus (HBV) and hepatitis D virus (HDV). In this study we aimed to ch
Externí odkaz:
https://doaj.org/article/3cba6396885a4f29bfcfe777bdb7a6e9
Autor:
Antoaneta A Markova, Ulrike Mihm, Verena Schlaphoff, Sebastian Lunemann, Natalie Filmann, Birgit Bremer, Thomas Berg, Christoph Sarrazin, Stefan Zeuzem, Michael P Manns, Markus Cornberg, Eva Herrmann, Heiner Wedemeyer
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94512 (2014)
Ribavirin (RBV) remains part of several interferon-free treatment strategies even though its mechanisms of action are still not fully understood. One hypothesis is that RBV increases responsiveness to type I interferons. Pegylated Interferon alpha (P
Externí odkaz:
https://doaj.org/article/4e3b9b2386f5441eaf7e39811ea37044
Autor:
Verena Schlaphoff, Sebastian Lunemann, Pothakamuri Venkata Suneetha, Jerzy Jaroszewicz, Jan Grabowski, Julia Dietz, Fabian Helfritz, Hueseyin Bektas, Christoph Sarrazin, Michael Peter Manns, Markus Cornberg, Heiner Wedemeyer
Publikováno v:
PLoS Pathogens, Vol 7, Iss 5, p e1002045 (2011)
The outcome of viral infections is dependent on the function of CD8+ T cells which are tightly regulated by costimulatory molecules. The NK cell receptor 2B4 (CD244) is a transmembrane protein belonging to the Ig superfamily which can also be express
Externí odkaz:
https://doaj.org/article/2834350100cf463fa8f1f03781eda727
Autor:
H. Wedemeyer, Katja Deterding, Verena Schlaphoff, Benedikt Strunz, Julia Hengst, Niklas K. Björkström, Hans-Gustaf Ljunggren, M.P. Manns
Publikováno v:
Zeitschrift für Gastroenterologie. 54:1343-1404
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b8afa4714b94ecc043cb6c903b1cffb
https://doi.org/10.1055/s-0036-1597523
https://doi.org/10.1055/s-0036-1597523
Autor:
Markus Cornberg, Verena Schlaphoff, Heiner Wedemeyer, Svenja Hardtke, Sebastian Lunemann, Katja Deterding, Julia Hengst, Michael P. Manns, Andreas L. Klein, Christine S. Falk
The natural course of acute Hepatitis C Virus (aHCV) infection is highly heterogeneous, and only few biomarkers have been identified to reliably predict the outcome of infection. We analysed a large panel of soluble inflammatory mediators, immune cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01e81d5e28c2f4ea4d261b963e2708f5
https://www.ncbi.nlm.nih.gov/pubmed/30548086
https://www.ncbi.nlm.nih.gov/pubmed/30548086
Autor:
Markus Cornberg, Solomon Owusu Sekyere, Jan Grabowski, Thomas Schirdewahn, Verena Schlaphoff, Heiner Wedemeyer, Birgit Bremer, A. Wranke, J. Kirschner, Pothakamuri Venkata Suneetha, Michael P. Manns, Svenja Hardtke, Sebastian Lunemann
Publikováno v:
Journal of Infectious Diseases. 215:139-149
Background Hepatitis D virus (HDV) infection affects 15-20 million individuals worldwide and causes severely progressive hepatitis. It is unknown to what extent cellular immune responses contribute to liver disease and control of viral replication in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::147b3820e9e98122748f5ec4c193d86b
https://doi.org/10.1093/infdis/jiw514
https://doi.org/10.1093/infdis/jiw514
Autor:
Christine S. Falk, Verena Schlaphoff, Katja Deterding, Markus Cornberg, Heiner Wedemeyer, Michael P. Manns, Julia Hengst
Publikováno v:
Journal of Infectious Diseases. 214:1965-1974
Background Persistent infection with hepatitis C virus (HCV) causes profound alterations of the cytokine and chemokine milieu in peripheral blood. However, it is unknown to what extend these alterations affect the progression of liver disease and whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f35a1ab754b02fef54e2662c99396f
https://doi.org/10.1093/infdis/jiw457
https://doi.org/10.1093/infdis/jiw457
Autor:
Michael P. Manns, Markus Cornberg, Heiner Wedemeyer, Kim Haag, Birgit Bremer, Meike Dirks, Karin Weissenborn, Henning Pflugrad, Julia Hengst, Ramona Schuppner, Verena Schlaphoff, Christine S. Falk, Amare Aregay, Solomon Owusu Sekyere
Background & aims Chronic inflammatory liver diseases are frequently associated with neuropsychiatric and cognitive dysfunctions. We hypothesized that symptomatic patients may show altered levels of soluble inflammatory mediators (SIMs) as well as ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6776efc8072826446d4716b07a9803cc
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85057173254
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85057173254
Autor:
Roland Jacobs, P. Fytili, Christoph Klade, Markus Cornberg, Michael P. Manns, Heiner Wedemeyer, Pothakamuri Venkata Suneetha, Rakesh K. Bakshi, Gustavo Fioravanti Vieira, Anke R. M. Kraft, Shihong Zhang, Dinler A. Antunes, Verena Schlaphoff
Publikováno v:
Journal of Virology. 89:8304-8317
T cell responses play a critical role in controlling or clearing viruses. Therefore, strategies to prevent or treat infections include boosting T cell responses. T cells specific for various pathogens have been reported in unexposed individuals and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3ba90782211ee02b44fe45082cec4fa
https://doi.org/10.1128/jvi.00539-15
https://doi.org/10.1128/jvi.00539-15