Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Verena Rohnalter"'
Autor:
Matthias Lauth, Martin E. Fernandez-Zapico, Michael Krause, Robert R. McWilliams, Maite G. Fernandez-Barrena, Anne M. Vrabel, Philipp S. Holz, Verena Rohnalter, Luciana L. Almada, Simon Joost
PDf file - 405K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::928038b0c65a00e613be531becfe4cc5
https://doi.org/10.1158/0008-5472.22393574.v1
https://doi.org/10.1158/0008-5472.22393574.v1
Autor:
Simon Joost, Martin E. Fernandez-Zapico, Philipp Simon Holz, Verena Rohnalter, Maite G. Fernandez-Barrena, Matthias Lauth, Robert R. McWilliams, Luciana L. Almada, Michael Krause, Anne M. Vrabel
Publikováno v:
Cancer Research. 72:88-99
The Hedgehog (HH) pathway has been identified as an important deregulated signal transduction pathway in pancreatic ductal adenocarcinoma (PDAC), a cancer type characterized by a highly metastatic phenotype. In PDAC, the canonical HH pathway activity
Autor:
Rune Toftgård, Matthias Lauth, Mahsa Kooshesh, Verena Rohnalter, Per Svenningsson, Åsa Bergström
Publikováno v:
Molecular Pharmacology. 78:486-496
Recently we identified GANT61, a small-molecule antagonist of Gli transcription factors, which are the final effectors of the mammalian Hedgehog (HH) signaling pathway. Here we describe a diamine substructure of GANT61 that carries the biological act
Autor:
Julia Obert, Kristina Dorzweiler, Sabine Müller-Brüsselbach, Florian Finkernagel, Katrin Roth, Verena Rohnalter, Till Adhikary, Rolf Müller, Maike Bensberg
Publikováno v:
Oncotarget
DNA-damaging drugs induce a plethora of molecular and cellular alterations in tumor cells, but their interrelationship is largely obscure. Here, we show that carboplatin treatment of human ovarian carcinoma SKOV3 cells triggers an ordered sequence of
Autor:
Philipp Simon Holz, Simon Joost, Matthias Lauth, Maite G. Fernandez-Barrena, Martin E. Fernandez-Zapico, Verena Rohnalter, Luciana L. Almada
Publikováno v:
Cancer Research. 72:3704-3705
In a recent publication ([1][1]), we showed that low levels of the GLI1 transcription factor sensitize pancreatic ductal adenocarcinoma (PDAC) cells to induce an epithelial-to-mesenchymal transition (EMT). Analysis of the mechanism identified E-cadhe