Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Verena Mantke"'
Autor:
Carsten Müller-Tidow, Georg Lenz, Heike Hintelmann, Lars Henning Schmidt, Wolfgang E. Berdel, Saliha Harrach, Carsten Höltke, Christoph Schliemann, Verena Mantke, Janine Stucke-Ring, Caroline Brand, Torsten Kessler, Rolf M. Mesters, Wolfgang Hartmann, Eva Wardelmann, Christian Schwöppe, Julian Timo Ronnacker, Bernhard Wünsch
Publikováno v:
Oncotarget
Truncated tissue factor (tTF), retargeted to tumor vasculature by GNGRAHA peptide (tTF-NGR), and doxorubicin have therapeutic activity against a variety of tumors. We report on combination experiments of both drugs using different schedules. We have
Autor:
Christian Schwöppe, Christoph Schliemann, Verena Mantke, Martin Lücke, Caroline Brand, Janine Ring, Rolf M. Mesters, Wolfgang E. Berdel, Max Fröhlich, Torsten Kessler, Simone König
Publikováno v:
Molecular Pharmaceutics. 12:3749-3758
tTF-NGR retargets the extracellular domain of tissue factor via a C-terminal peptide GNGRAHA, a ligand of the surface protein aminopeptidase N (CD13) and upon deamidation of integrin αvβ3, to tumor vasculature. tTF-NGR induces tumor vascular infarc
Autor:
Verena Mantke, Rolf M. Mesters, Wolfgang E. Berdel, Julian Timo Ronnacker, Janine Stucke-Ring, Carsten Höltke, Christoph Schliemann, Christian Schwöppe, Caroline Brand, Torsten Kessler
Publikováno v:
Cancer Research. 76:LB-223
Truncated tissue factor (tTF) retargeted to tumor vasculature by C-terminal GNGRAHA peptide (tTF-NGR) is able to induce tumor vessel infarction. Here, we describe the identification of the optimum therapeutic regimen for the use of tTF-NGR (or a rand