Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Verena Lutz"'
Autor:
Petros A. Hantzopoulos, Bernd Gansbacher, Olaf Wilhelm, Elena E Rojo, Manfred Schmitt, Achim Krüger, Verena Lutz, Henner Graeff, Viktor Magdolen, Rita Soeltl
Publikováno v:
Cancer Gene Therapy. 7:292-299
The serine protease urokinase-type plasminogen activator, uPA, when bound to its specific receptor, uPAR (CD87), plays a significant role in tumor cell invasion and metastasis. In breast cancer, enhanced uPA antigen in the primary tumor is correlated
Autor:
Georg Brunner, Manfred Schmitt, Verena Lutz, Viktor Magdolen, Sabine Wilhelm, Daniel B. Rifkin, Henner Graeff, Gemma M. Escott, Olaf Wilhelm, E. Lynette Wilson
Publikováno v:
Journal of Cellular Physiology. 180:225-235
The glycosylphosphatidylinositol (GPI)-anchored, multifunctional receptor for the serine proteinase, urokinase plasminogen activator (uPAR, CD87), regulates plasminogen activation and cell migration, adhesion, and proliferation. uPAR occurs in functi
Autor:
Tobias Ullrich, Nadia Harbeck, Ronald E. Kates, Manfred Schmitt, Marion Kiechle, Silvia Riemer, Katharina Seck, Robert B. Diasio, Eva Gross, Verena Lutz
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 11(16)
Purpose: Complete or partial loss of dihydropyrimidine dehydrogenase (DPD) function has been described in cancer patients with intolerance to fluoropyrimidine drugs like 5-fluorouracil (5-FU) or Xeloda. The intention of this population study is to as
Autor:
Marion Kiechle, Verena Lutz, Heide Hellebrand, Steffi Neubauer, Adisorn Ratanaphan, Eva Gross, Hubertus Stockinger, Katharina Seck, Jutta Mayr
Publikováno v:
International journal of oncology. 22(2)
Dihydropyrimidine dehydrogenase (DPD) is the first and rate-limiting enzyme in the degradation of pyrimidines and pyrimidine base analogs including the anticancer drugs 5-fluorouracil (5-FU) and Xeloda. A decreased DPD enzyme activity has been descri
Publikováno v:
The Plant journal : for cell and molecular biology. 19(2)
Summary We investigated the P450 dependent flavonoid hydroxylase from the ornamental plant Catharanthus roseus. cDNAs were obtained by heterologous screening with the CYP75 Hf1 cDNA from Petunia hybrida. The C. roseus protein shared 68–78% identity
Autor:
Nadia Harbeck, Peter Heiss, Olaf Wilhelm, Kerstin Fischer, Horst Kessler, Ute Reuning, Thomas Luther, Verena Lutz, Viktor Magdolen, Tomizo Nishiguchi, Henner Graeff, Manfred Schmitt
Publikováno v:
FEBS letters. 438(1-2)
Ovarian cancer metastasis is associated with an increase in the urokinase-type plasminogen activator (uPA) and its receptor uPAR. We present evidence that binding of uPA to uPAR provokes a mitogenic response in the human ovarian cancer cell line OV-M
Autor:
H.-P. Kuo, Anna Pluzanska, Verena Lutz, José Baselga, Mark M. Kockx, Laurent Essioux, Rodryg Ramlau, Eng Huat Tan, Máximo Carreras, Barbara Klughammer
Publikováno v:
Journal of Thoracic Oncology. (8):S394-S395