Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Verena Kluever"'
Autor:
Tal M. Dankovich, Rahul Kaushik, Linda H. M. Olsthoorn, Gabriel Cassinelli Petersen, Philipp Emanuel Giro, Verena Kluever, Paola Agüi-Gonzalez, Katharina Grewe, Guobin Bao, Sabine Beuermann, Hannah Abdul Hadi, Jose Doeren, Simon Klöppner, Benjamin H. Cooper, Alexander Dityatev, Silvio O. Rizzoli
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-23 (2021)
Synapses are surrounded by an extracellular matrix (ECM) of extremely long-lived proteins that is thought to only be remodeled by proteolysis and de novo synthesis. Here, the authors show an alternative molecular recycling mechanism that occurs for t
Externí odkaz:
https://doaj.org/article/3f8c8045f2374bd4b5f68c1454eccc00
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4615 (2022)
Nano secondary ion mass spectrometry (nanoSIMS) imaging is a rapidly growing field in biological sciences, which enables investigators to describe the chemical composition of cells and tissues with high resolution. One of the major challenges of nano
Externí odkaz:
https://doaj.org/article/e542ba4709e04256ba938899f4fa9a6c
Autor:
Roya Yousefi, Kristina Jevdokimenko, Verena Kluever, David Pacheu-Grau, Eugenio F. Fornasiero
Publikováno v:
Cells, Vol 10, Iss 7, p 1747 (2021)
Protein homeostasis is an equilibrium of paramount importance that maintains cellular performance by preserving an efficient proteome. This equilibrium avoids the accumulation of potentially toxic proteins, which could lead to cellular stress and dea
Externí odkaz:
https://doaj.org/article/07b9ebb2b70141b09dd11adeaab3ddec
Publikováno v:
Molecules, Vol 26, Iss 13, p 3951 (2021)
The extraordinary cellular diversity and the complex connections established within different cells types render the nervous system of vertebrates one of the most sophisticated tissues found in living organisms. Such complexity is ensured by numerous
Externí odkaz:
https://doaj.org/article/68a36a3ee4cc42c2a5fc5c492f4d4f7a
Autor:
Verena Kluever, Belisa Russo, Sunit Mandad, Nisha Hemandhar Kumar, Mihai Alevra, Alessandro Ori, Silvio O. Rizzoli, Henning Urlaub, Anja Schneider, Eugenio F. Fornasiero
Publikováno v:
Science advances 8(20), eabn4437 (2022). doi:10.1126/sciadv.abn4437
Science Advances
Science Advances
Aging is a prominent risk factor for neurodegenerative disorders (NDDs); however, the molecular mechanisms rendering the aged brain particularly susceptible to neurodegeneration remain unclear. Here, we aim to determine the link between physiological
Autor:
Kristina Jevdokimenko, Eugenio F. Fornasiero, Verena Kluever, Roya Yousefi, David Pacheu-Grau
Publikováno v:
Cells
Volume 10
Issue 7
Cells, Vol 10, Iss 1747, p 1747 (2021)
Volume 10
Issue 7
Cells, Vol 10, Iss 1747, p 1747 (2021)
Protein homeostasis is an equilibrium of paramount importance that maintains cellular performance by preserving an efficient proteome. This equilibrium avoids the accumulation of potentially toxic proteins, which could lead to cellular stress and dea
Autor:
Tal M. Dankovich, Rahul Kaushik, Linda H. M. Olsthoorn, Gabriel Cassinelli Petersen, Philipp Emanuel Giro, Verena Kluever, Paola Agüi-Gonzalez, Katharina Grewe, Guobin Bao, Sabine Beuermann, Hannah Abdul Hadi, Jose Doeren, Simon Klöppner, Benjamin H. Cooper, Alexander Dityatev, Silvio O. Rizzoli
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-23 (2021)
Nature Communications 12(1), 7129 (2021). doi:10.1038/s41467-021-27462-7
Nature Communications, Vol 12, Iss 1, Pp 1-23 (2021)
Nature Communications 12(1), 7129 (2021). doi:10.1038/s41467-021-27462-7
The brain extracellular matrix (ECM) consists of extremely long-lived proteins that assemble around neurons and synapses, to stabilize them. The ECM is thought to change only rarely, in relation to neuronal plasticity, through ECM proteolysis and ren
Autor:
Eugenio F. Fornasiero, Verena Kluever
Publikováno v:
Ageing Research Reviews. 72:101465
Due to the extension of human life expectancy, the prevalence of cognitive impairment is rising in the older portion of society. Developing new strategies to delay or attenuate cognitive decline is vital. For this purpose, it is imperative to underst
Autor:
Verena Kluever, Stefan Bonn, Vikas Bansal, Henning Urlaub, J. D. Wren, Silvio O. Rizzoli, E. Fritsch, Eugenio F. Fornasiero, Annette Gärtner, L. Caldi Gomes, Sunit Mandad, Raza-Ur Rahman, Sarva Keihani, S. Kügler
Publikováno v:
Science advances 5(12), eaay2670 (2019). doi:10.1126/sciadv.aay2670
Science Advances
Science Advances
NeuroLNC, a previously unknown long ncRNA, regulates neuronal activity by interacting with the neurodegeneration protein TDP-43.
The cellular and the molecular mechanisms by which long noncoding RNAs (lncRNAs) may regulate presynaptic function a
The cellular and the molecular mechanisms by which long noncoding RNAs (lncRNAs) may regulate presynaptic function a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b2243aba061417eff0d84ab59446606
http://resolver.sub.uni-goettingen.de/purl?gs-1/17142
http://resolver.sub.uni-goettingen.de/purl?gs-1/17142
Autor:
Sinthuya Thavaneetharajah, Ursula Felderhoff-Mueser, Astrid Bertsche, Laura Lueckemann, Ivo Bendix, Katja Strasser, Verena Kluever, Joachim Fandrey, Daniela Hoeber
Publikováno v:
Brain research. 1646
Perinatal asphyxia to the developing brain remains a major cause of morbidity. Hypothermia is currently the only established neuroprotective treatment available for term born infants with hypoxic-ischemic encephalopathy, saving one in seven to eight