Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Verena K. Raker"'
Autor:
Kaan Yilmaz, Stefanie Haeberle, Yong Ook Kim, Marvin J. Fritzler, Shih-Yen Weng, Benjamin Goeppert, Verena K. Raker, Kerstin Steinbrink, Detlef Schuppan, Alexander Enk, Eva N. Hadaschik
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionScurfy mice have a complete deficiency of functional regulatory T cells (Treg) due to a frameshift mutation in the Foxp3 gene. The impaired immune homeostasis results in a lethal lymphoproliferative disorder affecting multiple organs, inc
Externí odkaz:
https://doaj.org/article/a696944eb6ae4402b9488c883c8f0378
Autor:
Kerstin Johann, Toszka Bohn, Fatemeh Shahneh, Natascha Luther, Alexander Birke, Henriette Jaurich, Mark Helm, Matthias Klein, Verena K. Raker, Tobias Bopp, Matthias Barz, Christian Becker
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
The acidic tumour microenvironment in melanoma drives immune evasion by cAMP in tumor-infiltrating monocytes. Here, the authors show that the release of an adenylate cyclase inhibitor from micelles restores antitumor immunity and, when combined with
Externí odkaz:
https://doaj.org/article/7bf68961413a4a0db798c0e43c2d024c
Publikováno v:
Cells, Vol 9, Iss 9, p 2063 (2020)
Interleukin-2 (IL-2) is a T cell growth factor particularly required in regulatory T cell maintenance and memory T cell responses. High-dose IL-2 treatment was the first FDA-approved immunotherapy for cancer, while low-dose IL-2 administration has sh
Externí odkaz:
https://doaj.org/article/bf494585f35e4983ba507c8170b761d3
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Dendritic cells (DCs) are central players in the initiation and control of responses, regulating the balance between tolerance and immunity. Tolerogenic DCs are essential in the maintenance of central and peripheral tolerance by induction of clonal T
Externí odkaz:
https://doaj.org/article/269ad267cf4b4d81835ba41f07ec4a51
Autor:
Maria Isabel Fleischer, Nadine Röhrig, Verena K. Raker, Juliane Springer, Detlef Becker, Sandra Ritz, Matthias Bros, Henner Stege, Maximilian Haist, Stephan Grabbe, Jessica Haub, Christian Becker, Sabine Reyda, Jennifer Disse, Talkea Schmidt, Karsten Mahnke, Hartmut Weiler, Wolfram Ruf, Kerstin Steinbrink
Publikováno v:
Journal of thrombosis and haemostasis : JTHREFERENCES. 20(12)
Protease-activated receptor 2 (PAR2) signaling controls skin barrier function and inflammation, but the roles of immune cells and PAR2-activating proteases in cutaneous diseases are poorly understood.To dissect PAR2 signaling contributions to skin in
Autor:
Sabrina Muecklich, Khuram Shehzad, Jessica Tiemann, Li Li, Sonja Leson, Peter J. Nelson, Richard Jennemann, Matthias Klein, Christian Becker, Roger Sandhoff, Kerstin Steinbrink, Verena K. Raker
Publikováno v:
The Journal of investigative dermatology.