Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Verena K. Maier"'
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100819- (2021)
Summary: The isolation of protein-RNA complexes in the “denaturing cross-linked RNA immunoprecipitation” (dCLIP) protocol is based on biotin-tagging proteins of interest, UV cross-linking RNA to protein in vivo, RNase protection assay, and isolat
Externí odkaz:
https://doaj.org/article/b65798577737407a813672ec527aad2f
Publikováno v:
Journal of Exposure Science & Environmental Epidemiology. 28:69-75
Exposure limit values give the exposure level at which an accepted (or acceptable) number of additional work related diseases are expected. The values are derived from dose-response curves and carry a large amount of uncertainty. In this paper we aim
Publikováno v:
Journal of Agricultural, Biological, and Environmental Statistics. 20:353-370
We observe a group of pigs over a period of about 100 days. Using high frequency radio frequency identification, it is recorded when each pig is feeding, leading to very dense binary functional data for each pig and day. One aim of the data analysis
Autor:
Catherine Cifuentes-Rojas, Jacob D. Jaffe, Jeannie T. Lee, Jana W. Qiao, Attila Szanto, Amanda L. Creech, Steven A. Carr, Nicholas Chevrier, Philipp Mertins, Partha Pratim Das, Caitlin M. Feeney, Stuart H. Orkin, Jordan E. Taylor, Verena K. Maier
Publikováno v:
Molecular & Cellular Proteomics. 14:1435-1446
Cell-type specific gene silencing by histone H3 lysine 27 and lysine 9 methyltransferase complexes PRC2 and G9A-GLP is crucial both during development and to maintain cell identity. Although studying their interaction partners has yielded valuable in
Autor:
Jeannie T. Lee, Sally E. Peach, Jesse S. Boehm, Amanda L. Creech, Verena K. Maier, Jacob D. Jaffe, Caitlin M. Feeney, Namrata D. Udeshi, Jordan E. Taylor, Steven A. Carr, Xiaoyun Wu
Publikováno v:
Methods. 72:57-64
Epigenetic control of genome function is an important regulatory mechanism in diverse processes such as lineage commitment and environmental sensing, and in disease etiologies ranging from neuropsychiatric disorders to cancer. Here we report a robust
Publikováno v:
Cell systems. 5(4)
Summary Interaction networks between chromatin complexes and long noncoding RNAs have become a recurrent theme in epigenetic regulation. However, technical limitations have precluded identification of RNA binding motifs for chromatin-associated prote
Autor:
Caroline J. Woo, Verena K. Maier, Roshni Davey, James Brennan, Guangde Li, John Brothers, Brian Schwartz, Susana Gordo, Anne Kasper, Trevor R. Okamoto, Hans E. Johansson, Berhan Mandefro, Dhruv Sareen, Peter Bialek, B. Nelson Chau, Balkrishen Bhat, David Bullough, James Barsoum
Publikováno v:
Proceedings of the National Academy of Sciences. 114
Significance Autosomal recessive mutations or deletions of the gene Survival Motor Neuron 1 ( SMN1 ) cause spinal muscular atrophy, a neurodegenerative disorder. Transcriptional up-regulation of a nearly identical gene, SMN2 , can functionally compen
Autor:
Helmut Küchenhoff, Alexandra Schneider, Susanne Breitner, Uta Geruschkat, Jianwei Gu, Annette Peters, Verena K. Maier, Veronika Deffner, Josef Cyrys, Mike Pitz
Publikováno v:
Journal of Exposure Science & Environmental Epidemiology. 26:17-25
Personal exposure to air pollution is associated with time- and location-specific factors including indoor and outdoor air pollution, meteorology and time activities. Our investigation aims at the description and identification of factors determining
Publikováno v:
bchm. 389:345-352
Chromatin serves to package, protect and organize the complex eukaryotic genomes to assure their stable inheritance over many cell generations. At the same time, chromatin must be dynamic to allow continued use of DNA during a cell's lifetime. One im
Publikováno v:
The EMBO Journal. 27:817-826
Nucleosome-remodelling factors containing the ATPase ISWI, such as ACF, render DNA in chromatin accessible by promoting the sliding of histone octamers. Although the ATP-dependent repositioning of mononucleosomes is readily observable in vitro, it is