Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Verena K. Hehle"'
Autor:
Marcello Donini, Mathew J. Paul, Eugenio Benvenuto, Veronica Morea, Craig J. van Dolleweerd, Verena K. Hehle, Patrizio Di Micco, Raffaele Lombardi, Julian K.-C. Ma
Publikováno v:
Plant biotechnology journal
13 (2015): 235–245. doi:10.1111/pbi.12266
info:cnr-pdr/source/autori:Hehle, Verena K.; Lombardi, Raffaele; Van Dolleweerd, Craig J.; Paul, Mathew J.; Di Micco, Patrizio; Morea, Veronica; Benvenuto, Eugenio; Donini, Marcello; Ma, Julian/titolo:Site-specific proteolytic degradation of IgG monoclonal antibodies expressed in tobacco plants/doi:10.1111%2Fpbi.12266/rivista:Plant biotechnology journal (Print)/anno:2015/pagina_da:235/pagina_a:245/intervallo_pagine:235–245/volume:13
13 (2015): 235–245. doi:10.1111/pbi.12266
info:cnr-pdr/source/autori:Hehle, Verena K.; Lombardi, Raffaele; Van Dolleweerd, Craig J.; Paul, Mathew J.; Di Micco, Patrizio; Morea, Veronica; Benvenuto, Eugenio; Donini, Marcello; Ma, Julian/titolo:Site-specific proteolytic degradation of IgG monoclonal antibodies expressed in tobacco plants/doi:10.1111%2Fpbi.12266/rivista:Plant biotechnology journal (Print)/anno:2015/pagina_da:235/pagina_a:245/intervallo_pagine:235–245/volume:13
Plants are promising hosts for the production of monoclonal antibodies (mAbs). However, proteolytic degradation of antibodies produced both in stable transgenic plants and using transient expression systems is still a major issue for efficient high-y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83a50a64228dd7f19fd7df22e70a8ce2
Wiley Online Library
Wiley Online Library
Autor:
Deborah K. Dunn-Walters, David D'Cruz, John Cason, Jo Spencer, Romeeza Tahir, LeeMeng Choong, Verena K. Hehle, Yu-Chang Wu, Pamela M. K. Lutalo, Andrew P. Cope, David Glyn Kipling, Louise D. Fraser
Publikováno v:
Molecular immunology. 65(2)
The unique specificity of the B cell receptor is generated by an ordered sequence of gene rearrangement events. Once IGH genes have rearranged, rearrangement at the IGK locus is initiated followed by the IGL locus if functional IGK rearrangement is n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::943e140cdc0147c85780e080f34f39bc
https://pubmed.ncbi.nlm.nih.gov/25700344
https://pubmed.ncbi.nlm.nih.gov/25700344
Autor:
Craig J. van Dolleweerd, Verena K. Hehle, Matthew J. Paul, Julian K.-C. Ma, Pascal M. W. Drake
Publikováno v:
BMC Biotechnology, Vol 11, Iss 1, p 128 (2011)
BMC Biotechnology
BMC Biotechnology
Background Interest in using plants for production of recombinant proteins such as monoclonal antibodies is growing, but proteolytic degradation, leading to a loss of functionality and complications in downstream purification, is still a serious prob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0257768c889ac316de2389031a8438c
https://doi.org/10.1186/1472-6750-11-128
https://doi.org/10.1186/1472-6750-11-128
Autor:
Tommaso Barbi, Sammy Ho, Mathew J. Paul, Leonard Both, Thais Guerra, Luisa De Moraes Madeira, Harry Thangaraj, Verena K. Hehle, Pascal M. W. Drake, Julian K.-C. Ma, Craig J. van Dolleweerd, Varghese Inchakalody, Rajko Reljic, Elena Stylianou, Ilaria Pepponi
Molecular Pharming represents an unprecedented opportunity to manufacture affordable modern medicines and make these available at a global scale. The area of greatest potential is in the prevention of infectious diseases, particular in underdeveloped
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86d319c3d2b06289c40874352d9664bd
https://europepmc.org/articles/PMC3230538/
https://europepmc.org/articles/PMC3230538/