Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Verena Köberle"'
Autor:
Oliver Waidmann, Thomas Pleli, Andreas Weigert, Esther Imelmann, Bianca Kakoschky, Christian Schmithals, Claudia Döring, Matthias Frank, Thomas Longerich, Verena Köberle, Martin-Leo Hansmann, Bernhard Brüne, Stefan Zeuzem, Albrecht Piiper, Ivan Dikic
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract The nuclear factor kappa beta (NFκB) signaling pathway plays an important role in liver homeostasis and cancer development. Tax1-binding protein 1 (Tax1BP1) is a regulator of the NFκB signaling pathway, but its role in the liver and hepato
Externí odkaz:
https://doaj.org/article/740d319af09b47b9b936f1021dead416
Autor:
Jan Peveling-Oberhag, Anna Seiz, Claudia Döring, Sylvia Hartmann, Verena Köberle, Juliane Liese, Stefan Zeuzem, Martin-Leo Hansmann, Albrecht Piiper
Publikováno v:
Translational Oncology, Vol 7, Iss 6, Pp 672-680 (2014)
Several microRNAs (miRNAs) are associated with the molecular pathogenesis of hepatocellular carcinoma (HCC). However, previous studies analyzing the dysregulation of miRNAs in HCC show heterogeneous results. We hypothesized that part of this heteroge
Externí odkaz:
https://doaj.org/article/9d0fda6cbca74428bc7aa4f259857012
Autor:
Thomas Pleli, Daniel Martin, Bernd Kronenberger, Friederike Brunner, Verena Köberle, Georgios Grammatikos, Harald Farnik, Yolanda Martinez, Fabian Finkelmeier, Sandra Labocha, Nerea Ferreirós, Stefan Zeuzem, Albrecht Piiper, Oliver Waidmann
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e103532 (2014)
BackgroundAutotaxin (ATX) and its product lysophosphatidic acid (LPA) are considered to be involved in the development of liver fibrosis and elevated levels of serum ATX have been found in patients with hepatitis C virus associated liver fibrosis. Ho
Externí odkaz:
https://doaj.org/article/f85ff14292e741c48d9e01f2f8ef19b1
Autor:
Verena Köberle, Thomas Pleli, Christian Schmithals, Eduardo Augusto Alonso, Jörg Haupenthal, Halvard Bönig, Jan Peveling-Oberhag, Ricardo M Biondi, Stefan Zeuzem, Bernd Kronenberger, Oliver Waidmann, Albrecht Piiper
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75184 (2013)
BACKGROUND: MicroRNAs circulating in the blood, stabilized by complexation with proteins and/or additionally by encapsulation in lipid vesicles, are currently being evaluated as biomarkers. The consequences of their differential association with lipi
Externí odkaz:
https://doaj.org/article/27cc2e82207f44788788a7973b7c1911
Autor:
Oliver Waidmann, Verena Köberle, Friederike Brunner, Stefan Zeuzem, Albrecht Piiper, Bernd Kronenberger
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45652 (2012)
BACKGROUND: Liver cirrhosis is associated with high morbidity and mortality. MicroRNAs (miRs) circulating in the blood are an emerging new class of biomarkers. In particular, the serum level of the liver-specific miR-122 might be a clinically useful
Externí odkaz:
https://doaj.org/article/79936cb691704adfad8abdfacd40e139
Autor:
Albrecht Piiper, Rolf Marschalek, Bernd Kronenberger, Andreas Weigert, Tobias Schmid, Horst-Werner Korf, Stefan Zeuzem, Fabian Finkelmeier, Oliver Waidmann, Scarlett Nitsch, Otto Kollmar, Thomas Pleli, Bianca Kakoschky, Verena Köberle, Erik Kowarz, Christian Schmithals, Ahmed Atef Ibrahim
Supplementary Fig. S3. Doxycyline-induced overexpression of Dicer in HCC cells. HepG2 (A) and Huh-7 (B) cells stably transfected with the inducible Dicer construct were incubated with or without doxycycline (Dox) for 24 h. C: HepG2 cells with the ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153173b78795cd01540a4b2857d672af
https://doi.org/10.1158/1078-0432.22466477.v1
https://doi.org/10.1158/1078-0432.22466477.v1
Autor:
Albrecht Piiper, Rolf Marschalek, Bernd Kronenberger, Andreas Weigert, Tobias Schmid, Horst-Werner Korf, Stefan Zeuzem, Fabian Finkelmeier, Oliver Waidmann, Scarlett Nitsch, Otto Kollmar, Thomas Pleli, Bianca Kakoschky, Verena Köberle, Erik Kowarz, Christian Schmithals, Ahmed Atef Ibrahim
Table S1. Clinicopathological parameters of the patients with HCC. HBV, hepatitis B virus; HCV, hepatitis C virus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a6865ed66d510950ea5367a566e7d6f
https://doi.org/10.1158/1078-0432.22466471
https://doi.org/10.1158/1078-0432.22466471
Autor:
Albrecht Piiper, Rolf Marschalek, Bernd Kronenberger, Andreas Weigert, Tobias Schmid, Horst-Werner Korf, Stefan Zeuzem, Fabian Finkelmeier, Oliver Waidmann, Scarlett Nitsch, Otto Kollmar, Thomas Pleli, Bianca Kakoschky, Verena Köberle, Erik Kowarz, Christian Schmithals, Ahmed Atef Ibrahim
Purpose: A role of Dicer, which converts precursor miRNAs to mature miRNAs, in the tumor-promoting effect of hypoxia is currently emerging in some tumor entities. Its role in hepatocellular carcinoma (HCC) is unknown.Experimental Design: HepG2 and Hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e0051240aeb319e2ddd4c696dd0bad3
https://doi.org/10.1158/1078-0432.c.6526325
https://doi.org/10.1158/1078-0432.c.6526325
Autor:
Albrecht Piiper, Rolf Marschalek, Bernd Kronenberger, Andreas Weigert, Tobias Schmid, Horst-Werner Korf, Stefan Zeuzem, Fabian Finkelmeier, Oliver Waidmann, Scarlett Nitsch, Otto Kollmar, Thomas Pleli, Bianca Kakoschky, Verena Köberle, Erik Kowarz, Christian Schmithals, Ahmed Atef Ibrahim
Supplementary Information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20816ba146821c93fd1d8d962e308247
https://doi.org/10.1158/1078-0432.22466474.v1
https://doi.org/10.1158/1078-0432.22466474.v1
Autor:
Albrecht Piiper, Oliver Waidmann, Thomas J. Vogl, Stefan Zeuzem, Bernd Kronenberger, Horst-Werner Korf, Bernd Groner, Vida Vafaizadeh, Jose M. Arencibia, Ahmed Atef Ibrahim, Eduardo Alonso Augusto, Bianca Kakoschky, Thomas Pleli, Hüdayi Korkusuz, Verena Köberle, Christian Schmithals
Supplementary Figure S3: Body weight of HepG2 (A) and Huh-7 (B) xenograft-bearing mice treated with iRGD, control (Ctl.) peptide, PBS and sorafenib (Sora).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162248249a6792df0df3f94c810a6ab0
https://doi.org/10.1158/0008-5472.22405320
https://doi.org/10.1158/0008-5472.22405320