Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Verena Horneffer van der Sluis"'
Autor:
James L. Alexander, Joram M. Posma, Alasdair Scott, Liam Poynter, Sam E. Mason, M. Luisa Doria, Lili Herendi, Lauren Roberts, Julie A. K. McDonald, Simon Cameron, David J. Hughes, Vaclav Liska, Simona Susova, Pavel Soucek, Verena Horneffer-van der Sluis, Maria Gomez-Romero, Matthew R. Lewis, Lesley Hoyles, Andrew Woolston, David Cunningham, Ara Darzi, Marco Gerlinger, Robert Goldin, Zoltan Takats, Julian R. Marchesi, Julian Teare, James Kinross
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-14 (2023)
Abstract Background and aims The gut microbiota is implicated in the pathogenesis of colorectal cancer (CRC). We aimed to map the CRC mucosal microbiota and metabolome and define the influence of the tumoral microbiota on oncological outcomes. Method
Externí odkaz:
https://doaj.org/article/12e07005f08c4eff961ce1c2bc1eb63e
Autor:
Constantin von Bibra, Aya Shibamiya, Andrea Bähr, Birgit Geertz, Maria Köhne, Tim Stuedemann, Jutta Starbatty, Verena Horneffer-van der Sluis, Ulrich C. Klostermeier, Nadja Hornaschewitz, Xinghai Li, Eckhard Wolf, Nikolai Klymiuk, Markus Krane, Christian Kupatt, Bernhard Hiebl, Thomas Eschenhagen, Florian Weinberger
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 5 (2023)
Externí odkaz:
https://doaj.org/article/b2f866000a454c14a8dba3101b884926
Autor:
James L. Alexander, Benjamin H. Mullish, Nathan P. Danckert, Zhigang Liu, Marton L. Olbei, Aamir Saifuddin, Melissa Torkizadeh, Hajir Ibraheim, Jesús Miguéns Blanco, Lauren A. Roberts, Claire M. Bewshea, Rachel Nice, Simeng Lin, Hemanth Prabhudev, Caroline Sands, Verena Horneffer-van der Sluis, Matthew Lewis, Shaji Sebastian, Charlie W. Lees, Julian P. Teare, Ailsa Hart, James R. Goodhand, Nicholas A. Kennedy, Tamas Korcsmaros, Julian R. Marchesi, Tariq Ahmad, Nick Powell
Publikováno v:
EBioMedicine, Vol 88, Iss , Pp 104430- (2023)
Summary: Background: Patients with inflammatory bowel disease (IBD) treated with anti-TNF therapy exhibit attenuated humoral immune responses to vaccination against SARS-CoV-2. The gut microbiota and its functional metabolic output, which are perturb
Externí odkaz:
https://doaj.org/article/81748891479c4744b4c014c27869b064
Autor:
Dulce Lima Cunha, Rose Richardson, Dhani Tracey-White, Alessandro Abbouda, Andreas Mitsios, Verena Horneffer-van der Sluis, Panteleimon Takis, Nicholas Owen, Jane Skinner, Ailsa A. Welch, Mariya Moosajee
Publikováno v:
JCI Insight, Vol 6, Iss 9 (2021)
Choroideremia (CHM) is an X-linked recessive chorioretinal dystrophy caused by mutations in CHM, encoding for Rab escort protein 1 (REP1). Loss of functional REP1 leads to the accumulation of unprenylated Rab proteins and defective intracellular prot
Externí odkaz:
https://doaj.org/article/a6a56a5b83ac4e6895eb2e14c85983ca
Autor:
Lianne R. de Haan, Joanne Verheij, Rowan F. van Golen, Verena Horneffer-van der Sluis, Matthew R. Lewis, Ulrich H. W. Beuers, Thomas M. van Gulik, Steven W. M. Olde Damink, Frank G. Schaap, Michal Heger, Pim B. Olthof
Publikováno v:
Biomolecules, Vol 11, Iss 2, p 260 (2021)
In a previous study, obeticholic acid (OCA) increased liver growth before partial hepatectomy (PHx) in rats through the bile acid receptor farnesoid X-receptor (FXR). In that model, OCA was administered during obstructive cholestasis. However, patien
Externí odkaz:
https://doaj.org/article/b4a5002f359f48138d9a366378ee7c6b
Autor:
James L. Alexander, Benjamin H. Mullish, Nathan P. Danckert, Zhigang Liu, Marton L. Olbei, Aamir Saifuddin, Melissa Torkizadeh, Hajir Ibraheim, Jesús Miguéns Blanco, Lauren A. Roberts, Claire M. Bewshea, Rachel Nice, Simeng Lin, Hemanth Prabhudev, Caroline Sands, Verena Horneffer-van der Sluis, Matthew Lewis, Shaji Sebastian, Charlie W. Lees, Julian P. Teare, Ailsa Hart, James R. Goodhand, Nicholas A. Kennedy, Tamas Korcsmaros, Julian R. Marchesi, Tariq Ahmad, Nick Powell
Background: Patients with inflammatory bowel disease (IBD) treated with anti-TNF therapy exhibit attenuated humoral immune responses to vaccination against SARS-CoV-2. The gut microbiota and its functional metabolic output, which are perturbed in IBD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33804616af1a673e332bc98865ac705
http://hdl.handle.net/10044/1/101403
http://hdl.handle.net/10044/1/101403
Autor:
Benjamin H. Mullish, Laura Martinez‐Gili, Elena Chekmeneva, Gonçalo D. S. Correia, Matthew R. Lewis, Verena Horneffer‐Van Der Sluis, Lauren A. Roberts, Julie A. K. McDonald, Alexandros Pechlivanis, Julian R. F. Walters, Emma L. McClure, Julian R. Marchesi, Jessica R. Allegretti
Background: Factors influencing recurrence risk in primary Clostridioides difficile infection (CDI) are poorly understood, and tools predicting recurrence are lacking. Perturbations in bile acids (BAs) contribute to CDI pathogenesis and may be releva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::933f0d210898b0c1142be93d362fb0e3
http://hdl.handle.net/10044/1/100250
http://hdl.handle.net/10044/1/100250
Autor:
Benjamin H. Mullish, Laura Martinez-Gili, Elena Chekmeneva, Gonçalo D. S. Correia, Matthew R. Lewis, Verena Horneffer-Van Der Sluis, Julie A. K. McDonald, Alexandros Pechlivanis, Julian R. F. Walters, Emma L McClure, Julian R. Marchesi, Jessica R. Allegretti
1.AbstractBackgroundFactors that influence recurrence risk in primary Clostridioides difficile infection (CDI) are poorly understood, and tools to predict recurrence are lacking. Perturbations in microbial-derived bile acids (BAs) contribute to CDI p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6e39b8169af413b1e7721255325684d
http://hdl.handle.net/10044/1/104368
http://hdl.handle.net/10044/1/104368
Autor:
James L Alexander, Benjamin H Mullish, Nathan P Danckert, Zhigang Liu, Aamir Saifuddin, Melissa Torkizadeh, Hajir Ibraheim, Jesús Miguéns Blanco, Lauren A Roberts, Claire M Bewshea, Rachel Nice, Simeng Lin, Hemanth Prabhudev, Caroline Sands, Verena Horneffer-van der Sluis, Matthew Lewis, Shaji Sebastian, Charlie W. Lees, Julian P Teare, Ailsa Hart, James R. Goodhand, Nicholas A. Kennedy, Julian R. Marchesi, Tariq Ahmad, Nick Powell
Patients with inflammatory bowel disease (IBD) treated with anti-TNF therapy exhibit attenuated humoral immune responses to vaccination against SARS-CoV-2. The gut microbiota and its functional metabolic output, which are perturbed in IBD, play an im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6135e6b45089fa186351e3d41c6ec76f
https://doi.org/10.21203/rs.3.rs-1672833/v1
https://doi.org/10.21203/rs.3.rs-1672833/v1
Autor:
Matthew Lewis, Elena Chekmeneva, Stephane Camuzeaux, Caroline Sands, Ada Yuen, Mark David, Ash Salam, Katie Chappell, Benjamin Cooper, Gordon Haggart, Lynn Maslen, María Gómez-Romero, Verena Horneffer-van der Sluis, Gonçalo Correia, Zoltan Takats
Metabolomics utilising liquid chromatography mass spectrometry (LC-MS) offers biomedical researchers a powerful means of assessing and comparing human phenotypes via measurement of the metabolome in biological samples. Platforms for LC-MS-based globa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5452cc731aa043f0e89b2580210d2ba
https://doi.org/10.26434/chemrxiv-2022-nq9k0
https://doi.org/10.26434/chemrxiv-2022-nq9k0