Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Verena Goebeler"'
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Mucosal epithelial cell integrity is an important component of innate immunity and it protects the host from an environment rich in microorganisms. Virulence factors from Gram-negative bacteria [e.g. lipopolysaccharide (LPS)] induce significant pro-i
Externí odkaz:
https://doaj.org/article/a3437439d7814df39575ec0c56ff20e9
Autor:
Ulrich Eckhard, Pitter F. Huesgen, Oliver Schilling, Caroline L. Bellac, Georgina S. Butler, Jennifer H. Cox, Antoine Dufour, Verena Goebeler, Reinhild Kappelhoff, Ulrich auf dem Keller, Theo Klein, Philipp F. Lange, Giada Marino, Charlotte J. Morrison, Anna Prudova, David Rodriguez, Amanda E. Starr, Yili Wang, Christopher M. Overall
Publikováno v:
Data in Brief, Vol 7, Iss , Pp 299-310 (2016)
The data described provide a comprehensive resource for the family-wide active site specificity portrayal of the human matrix metalloproteinase family. We used the high-throughput proteomic technique PICS (Proteomic Identification of protease Cleavag
Externí odkaz:
https://doaj.org/article/ea1cfb7a0a4643beb4babc346c545730
Autor:
Caroline L. Bellac, Antoine Dufour, Michael J. Krisinger, Anantasak Loonchanta, Amanda E. Starr, Ulrich auf dem Keller, Philipp F. Lange, Verena Goebeler, Reinhild Kappelhoff, Georgina S. Butler, Leslie D. Burtnick, Edward M. Conway, Clive R. Roberts, Christopher M. Overall
Publikováno v:
Cell Reports, Vol 9, Iss 2, Pp 618-632 (2014)
Resolution of inflammation reduces pathological tissue destruction and restores tissue homeostasis. Here, we used a proteomic protease substrate discovery approach, terminal amine isotopic labeling of substrates (TAILS), to analyze the role of the ma
Externí odkaz:
https://doaj.org/article/54232a9bc7164ad28c7741c5076d0c8e
Publikováno v:
Analytical Chemistry. 95:3291-3299
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology, Vol 12 (2021)
Mucosal epithelial cell integrity is an important component of innate immunity and it protects the host from an environment rich in microorganisms. Virulence factors from Gram-negative bacteria [e.g. lipopolysaccharide (LPS)] induce significant pro-i
Autor:
Alissa Cait, Diana Canals Hernaez, Bernard C. Lo, Hong B. Yu, Ido Refaeli, Verena Goebeler, Bruce A. Vallance, Samuel B. Shin, Kelly M. McNagny, William W. Mohn
Publikováno v:
The Journal of Immunology. 202:956-965
The cytokine IL-22 is rapidly induced at barrier surfaces where it regulates host-protective antimicrobial immunity and tissue repair but can also enhance disease severity in some chronic inflammatory settings. Using the chronic Salmonella gastroente
Autor:
Charlotte J. Morrison, Ulrich Eckhard, Reinhild Kappelhoff, Pitter F. Huesgen, Oliver Schilling, Giada Marino, Yili Wang, Jennifer H. Cox, Theo Klein, David Rodríguez, Verena Goebeler, Christopher M. Overall, Georgina S. Butler, Philipp F. Lange, Ulrich auf dem Keller, Antoine Dufour, Amanda E. Starr, Caroline L. Bellac, Anna Prudova
Publikováno v:
Matrix biology 49, 37-60 (2016). doi:10.1016/j.matbio.2015.09.003
Scopus
Matrix Biology, 49
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Scopus
Matrix Biology, 49
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Secreted and membrane tethered matrix metalloproteinases (MMPs) are key homeostatic proteases regulating the extracellular signaling and structural matrix environment of cells and tissues. For drug targeting of proteases, selectivity for individual m
Autor:
Bernard C, Lo, Samuel B, Shin, Diana, Canals Hernaez, Ido, Refaeli, Hong B, Yu, Verena, Goebeler, Alissa, Cait, William W, Mohn, Bruce A, Vallance, Kelly M, McNagny
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 202(3)
The cytokine IL-22 is rapidly induced at barrier surfaces where it regulates host-protective antimicrobial immunity and tissue repair but can also enhance disease severity in some chronic inflammatory settings. Using the chronic
Autor:
David S. Grierson, Jayakumar Surendradoss, Markus Heller, Edith Mary Dullaghan, Verena Goebeler, Christian Buchwalder, Ronan F. B. Gealageas, Pauline P. L. So, Catrina M. J. Kim, Alice Andree Valentine Devineau, Edward E. Putnins
Publikováno v:
Journal of medicinal chemistry. 61(16)
Studies indicate that MAO-B is induced in peripheral inflammatory diseases. To target peripheral tissues using MAO-B inhibitors that do not permeate the blood-brain barrier (BBB) the MAO-B-selective inhibitor deprenyl was remodeled by replacing the t
Autor:
Reinhild Kappelhoff, Antoine Dufour, Michael J. Krisinger, Christopher M. Overall, Verena Goebeler, Edward M. Conway, Ulrich auf dem Keller, Leslie D. Burtnick, Clive R. Roberts, Philipp F. Lange, Anantasak Loonchanta, Caroline L. Bellac, Amanda E. Starr, Georgina S. Butler
Publikováno v:
Cell Reports, 9 (2)
Cell Reports, Vol 9, Iss 2, Pp 618-632 (2014)
Cell Reports, Vol 9, Iss 2, Pp 618-632 (2014)
Resolution of inflammation reduces pathological tissue destruction and restores tissue homeostasis. Here, we used a proteomic protease substrate discovery approach, terminal amine isotopic labeling of substrates (TAILS), to analyze the role of the ma