Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Verena E.L. May"'
Autor:
Franz Marxreiter, Benjamin Ettle, Verena E.L. May, Hakan Esmer, Christina Patrick, Christine Lund Kragh, Jochen Klucken, Beate Winner, Olaf Riess, Jürgen Winkler, Eliezer Masliah, Silke Nuber
Publikováno v:
Neurobiology of Disease, Vol 59, Iss , Pp 38-51 (2013)
In Parkinson's disease (PD) patients, alpha-synuclein (α-syn) pathology advances in form of Lewy bodies and Lewy neurites throughout the brain. Clinically, PD is defined by motor symptoms that are predominantly attributed to the dopaminergic cell lo
Externí odkaz:
https://doaj.org/article/c105eda5863c4e4fa290d16245e9edf4
Autor:
Benjamin Ettle, Eliezer Masliah, Christina Patrick, Jürgen Winkler, Beate Winner, Christine Lund Kragh, Jochen Klucken, Silke Nuber, Franz Marxreiter, Hakan Esmer, Olaf Riess, Verena E.L. May
Publikováno v:
Neurobiology of Disease, Vol 59, Iss, Pp 38-51 (2013)
In Parkinson's disease (PD) patients, alpha-synuclein (α-syn) pathology advances in form of Lewy bodies and Lewy neurites throughout the brain. Clinically, PD is defined by motor symptoms that are predominantly attributed to the dopaminergic cell lo
Autor:
Kiren Ubhi, Eliezer Masliah, Anthony Adame, Chandra Inglis, Edward Rockenstein, Christina Patrick, Verena E.L. May, Michael Mante, Brian Spencer, Juergen Winkler
Publikováno v:
Experimental Neurology. 234:405-416
The term α-synucleinopathies refers to a group of age-related neurological disorders including Parkinson's disease (PD), Dementia with Lewy Bodies (DLB) and Multiple System Atrophy (MSA) that display an abnormal accumulation of alpha-synuclein (α-s
Autor:
Philipp Spitzer, Anne-Maria Poehler, Holger Meixner, J. Winkler, Oldriska Chutna, Edward Rockenstein, Verena E.L. May, Jochen Klucken, Tiago F. Outeiro, Wei Xiang, Eliezer Masliah
SNCA/α-synuclein aggregation plays a crucial role in synucleinopathies such as Parkinson disease and dementia with Lewy bodies. Aggregating and nonaggregating SNCA species are degraded by the autophagy-lysosomal pathway (ALP). Previously, we have sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::221eb1062fc7630513990e5ee1c28780
Autor:
Eliezer Masliah, Kiren Ubhi, Beate Winner, Jürgen Winkler, Benjamin Ettle, Michael Wegner, Edward Rockenstein, Silke Nuber, Anne-Maria Poehler, Verena E.L. May
Publikováno v:
Neurobiology of aging. 35(10)
Multiple system atrophy (MSA), an atypical parkinsonian disorder, is characterized by α-synuclein (α-syn+) cytoplasmatic inclusions in mature oligodendrocytes. Oligodendrocyte progenitor cells (OPCs) represent a distinct cell population with the po
Publikováno v:
Neuroscience. 222
Synucleinopathies including Parkinson's disease (PD) are characterized by the accumulation of alpha-synuclein (α-syn) within neural cell bodies and their processes. Transgenic mice overexpressing human wild-type or mutant forms of α-syn under the c
Autor:
Maren Bakkeboe, Antje Vogelgesang, Barbara M. Bröker, H. Wallaschofski, Soenke Langner, U. Grunwald, Christof Kessler, Verena E.L. May, Alexander Dressel
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 1, p e8718 (2010)
PLoS ONE, Vol 5, Iss 1, p e8718 (2010)
Stroke is a major cause of disability and leading cause of death in the northern hemisphere. Only recently it became evident that cerebral ischemia not only leads to brain tissue damage and subsequent local inflammation but also to a dramatic loss of