Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Verena B. Eisenbeis"'
Autor:
Tobias Dürr-Mayer, Danye Qiu, Verena B. Eisenbeis, Nicole Steck, Markus Häner, Alexandre Hofer, Andreas Mayer, Jay S. Siegel, Kim K. Baldridge, Henning J. Jessen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
The “anti-branching rule”, introduced in 1950, excludes branched polyphosphates from biological relevance due to their supposedly rapid hydrolysis. Here, the authors synthesize monodisperse branched polyphosphates and demonstrate their unexpected
Externí odkaz:
https://doaj.org/article/921f9a2b1f1c438c80bc3a9744880a07
Autor:
Danye Qiu, Miranda S. Wilson, Verena B. Eisenbeis, Robert K. Harmel, Esther Riemer, Thomas M. Haas, Christopher Wittwer, Nikolaus Jork, Chunfang Gu, Stephen B. Shears, Gabriel Schaaf, Bernd Kammerer, Dorothea Fiedler, Adolfo Saiardi, Henning J. Jessen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Myo-Inositol phosphates (InsPs) and pyrophosphates (PP-InsPs) are important second messengers but their analysis remains challenging. Here, the authors develop a capillary electrophoresis-mass spectrometry method for the identification and quantitati
Externí odkaz:
https://doaj.org/article/a6c9f68025794db3aaf128b31c15130b
Autor:
Verena B. Eisenbeis, Danye Qiu, Lisa Strotmann, Guizhen Liu, Isabel Prucker, Kevin Ritter, Christoph Loenarz, Adolfo Saiardi, Henning J. Jessen
1AbstractInositol pyrophosphates (PP-InsPs) are energetic signalling molecules with important functions in mammals. As their biosynthesis depends on ATP concentration, PP-InsPs are tightly connected to cellular energy homeostasis. Consequently, an in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65bf789a6cef6396d4efa09b21383c75
https://doi.org/10.1101/2022.11.27.518098
https://doi.org/10.1101/2022.11.27.518098
Autor:
Danye Qiu, Chunfang Gu, Guizhen Liu, Kevin Ritter, Verena B. Eisenbeis, Tamara Bittner, Artiom Gruzdev, Lea Seidel, Bertram Bengsch, Stephen B. Shears, Henning J. Jessen
Technical challenges have to date prevented a complete profiling of the levels of myo-inositol phosphates (InsPs) and pyrophosphates (PP-InsPs) in mammalian tissues. Here, we have deployed capillary electrophoresis mass spectrometry to identify and r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b43c809ae4b5a4c4046d4db43054eda
https://doi.org/10.1101/2022.09.14.507917
https://doi.org/10.1101/2022.09.14.507917
Publikováno v:
Journal of visualized experiments : JoVE. (174)
Inositol pyrophosphates (PP-InsPs) are an important group of intracellular signaling molecules. Derived from inositol phosphates (InsPs), these molecules feature the presence of at least one energetic pyrophosphate moiety on the myo-inositol ring. Th
Autor:
Min Gyu Kim, Hyungyu Min, Igor Pavlovic, Rho Hyun Seong, Eun-Ha Kim, Verena B. Eisenbeis, Wooseob Kim, Seyun Kim, Amit K. Dutta, Henning J. Jessen
Publikováno v:
Proceedings of the National Academy of Sciences. 116:12952-12957
T cell-independent (TI) B cell response is critical for the early protection against pathogen invasion. The regulation and activation of Bruton’s tyrosine kinase (Btk) is known as a pivotal step of B cell antigen receptor (BCR) signaling in TI humo
Autor:
Thomas M. Haas, Nikolaus Jork, Christoph Nopper, Claudia Jessen-Trefzer, Nicole Steck, Verena B. Eisenbeis, Tobias Dürr, Paul Ebensperger, Henning J. Jessen
Publikováno v:
Chemical Communications. 55:5339-5342
A tunable chemoenzymatic strategy provides access to the entire class of magic spot nucleotides and modified analogues. The approach combines chemoselective bisphosphorylations using phosphoramidites with regioselective ribonuclease T2 cyclo-phosphat
Autor:
Sebastian Hauke, Christopher Wittwer, Tamara Bittner, Dominik Bezold, Carsten Schultz, D. Thakor, Amit K. Dutta, Henning J. Jessen, Verena B. Eisenbeis, Igor Pavlovic
Publikováno v:
Chemical Science
β-Cells respond directly to the intracellular photochemical release of caged inositol pyrophosphate isomers with modulations of oscillations in cytosolic Ca2+.
Among many cellular functions, inositol pyrophosphates (PP-InsPs) are metabolic mess
Among many cellular functions, inositol pyrophosphates (PP-InsPs) are metabolic mess
Autor:
Robert K. Harmel, Nikolaus Jork, Bernd Kammerer, Danye Qiu, Thomas M. Haas, Chunfang Gu, Stephen B. Shears, Gabriel Schaaf, Miranda S. C. Wilson, Adolfo Saiardi, Christopher Wittwer, Esther Riemer, Verena B. Eisenbeis, Henning J. Jessen, Dorothea Fiedler
The analysis ofmyo-inositol phosphates (InsPs) andmyo-inositol pyrophosphates (PP-InsPs) is a daunting challenge due to the large number of possible isomers, the absence of a chromophore, the high charge density, the low abundance, and the instabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f09a6d7e8d6d4aa4415ec4d2b733eb4
https://doi.org/10.1101/2020.08.27.270405
https://doi.org/10.1101/2020.08.27.270405