Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Verena Materna"'
Autor:
Hermann Lage, Maciej Zabel, Manfred Dietel, Elzbieta Gebarowska, Barbara Dolinska-Krajewska, Marek Spaczynski, Irina Kaplenko, Verena Materna, Pawel Surowiak
Purpose: Cisplatin resistance is a major obstacle in the treatment of ovarian carcinoma. ABCC2 is commonly localized in apical cell membranes and could confer cisplatin resistance. Here, we show that ABCC2 can be localized in the cytoplasmic membrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62601d59a078fb6928c6a83bde95ce9f
https://doi.org/10.1158/1078-0432.c.6518445
https://doi.org/10.1158/1078-0432.c.6518445
Autor:
Hermann Lage, Maciej Zabel, Manfred Dietel, Elzbieta Gebarowska, Barbara Dolinska-Krajewska, Marek Spaczynski, Irina Kaplenko, Verena Materna, Pawel Surowiak
Supplementary Figures S1-S2 from ABCC2 (MRP2, cMOAT) Can Be Localized in the Nuclear Membrane of Ovarian Carcinomas and Correlates with Resistance to Cisplatin and Clinical Outcome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f1db5b6e7059149de9dcb93bcb6dca8
https://doi.org/10.1158/1078-0432.22441359
https://doi.org/10.1158/1078-0432.22441359
Autor:
Hermann Lage, Maciej Zabel, Manfred Dietel, Elzbieta Gebarowska, Barbara Dolinska-Krajewska, Marek Spaczynski, Irina Kaplenko, Verena Materna, Pawel Surowiak
Supplementary Table S1-S2 from ABCC2 (MRP2, cMOAT) Can Be Localized in the Nuclear Membrane of Ovarian Carcinomas and Correlates with Resistance to Cisplatin and Clinical Outcome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3abdc07e23e220d5f18a802e1747aeb6
https://doi.org/10.1158/1078-0432.22441356.v1
https://doi.org/10.1158/1078-0432.22441356.v1
Autor:
Annette Lebeau, Andreas Turzynski, Henning Adam, Simone Wesselmann, Stefan Rakowsky, Verena Materna
Publikováno v:
Krankenhaus-Report 2019 ISBN: 9783662582244
Telemedizin, definiert als arztliche Leistungserbringung uber raumliche oder zeitliche Distanz hinweg und unter Einsatz moderner Informations- und Kommunikationstechnologien, gewinnt auch in der Versorgung von Krebspatienten an Bedeutung. Die onkolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e011d5a0781c00ed4d7f902f4666a165
https://doi.org/10.1007/978-3-662-58225-1_11
https://doi.org/10.1007/978-3-662-58225-1_11
Autor:
Piotr Donizy, Pawel Surowiak, Jerzy Rabczyński, Verena Materna, Hermann Lage, Agnieszka Hałoń, Rafal Matkowski
Publikováno v:
Archives of Gynecology and Obstetrics
Objective To determine the prognostic value of the immunohistochemical evaluation of the multidrug resistance-associated protein 2 (MRP2) expression, together with its subcellular localization in primary fallopian tube carcinomas (PFTCs). Methods The
Autor:
Agnieszka Hałoń, Tserenchunt Gansukh, Manfred Dietel, Hermann Lage, Malgorzata Drag-Zalesinska, Marek Spaczyński, Maciej Zabel, Pawel Surowiak, Verena Materna, Piotr Donizy, Ewa Nowak-Markwitz
Publikováno v:
Pathology Oncology Research
Estrogen as a potential factor of ovarian carcinogenesis, acts via two nuclear receptors, estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ), but the cellular signal pathways involved are not completely clear so far. In this study we ha
Autor:
Józef Oleksyszyn, Verena Materna, M. Spaczyński, Hermann Lage, Maciej Zabel, Pawel Surowiak, Manfred Dietel, Slawomir Suchocki, Marcin Drąg, Renata Grzywa
Publikováno v:
International Journal of Gynecological Cancer. 16:1783-1788
Aminopeptidase N/CD13 (EC 3.4.11.2) is suggested to play a role in cancer cells invasion, and its activity can be inhibited using specific inhibitors. CD13 inhibitors evoke apoptosis of CD13-positive cancer cells. However, expression of CD13 has not
Autor:
Piotr Dziegiel, Balazs Gyorffy, Rafal Matkowski, Marek Pudełko, M. Zabel, Manfred Dietel, Pawel Surowiak, Glen Kristiansen, Piotr Paluchowski, Hermann Lage, Verena Materna, Jan Kornafel, Adam Maciejczyk, Andrzej Wojnar
Publikováno v:
British Journal of Cancer
Determination of oestrogen receptor alpha (ER) represents at present the most important predictive factor in breast cancers. Data of ours and of other authors suggest that promising predictive/prognostic factors may also include pS2, metallothionein
Autor:
Rafal Matkowski, Marek Pudełko, Pawel Surowiak, Manfred Dietel, Katarzyna Szczuraszek, Verena Materna, Carsten Denkert, Jan Kornafel, Maciej Zabel, Hermann Lage, Andrzej Wojnar
Publikováno v:
Breast Cancer Research
Introduction Recent reports suggest that expression of the cyclooxygenase 2 (COX-2) enzyme may up-regulate expression of MDR1/P-glycoprotein (MDR1/P-gp), an exponent of resistance to cytostatic drugs. The present study aimed at examining the relation
Autor:
Verena Materna, Maciej Zabel, Irina Kaplenko, Pawel Surowiak, Hermann Lage, Manfred Dietel, Marek Spaczyński
Publikováno v:
Virchows Archiv. 447:626-633
Resistance to cis- or carboplatin represents the principal cause of therapeutic failures in ovarian carcinoma. The phenomenon of resistance to platinum-based drugs is partly related to expression of metallothionein (MT) and of glutathione S-transfera