Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Verena, Steffen"'
Autor:
Heming Yao, PhD, Zhichao Wu, BAppSc(Optom), PhD, Simon S. Gao, PhD, Robyn H. Guymer, MBBS, PhD, Verena Steffen, MSc, Hao Chen, PhD, Mohsen Hejrati, PhD, Miao Zhang, PhD
Publikováno v:
Ophthalmology Science, Vol 4, Iss 3, Pp 100428- (2024)
Purpose: Nascent geographic atrophy (nGA) refers to specific features seen on OCT B-scans, which are strongly associated with the future development of geographic atrophy (GA). This study sought to develop a deep learning model to screen OCT B-scans
Externí odkaz:
https://doaj.org/article/2923b293db234d3684c1e211097b8e74
Autor:
Dolly S. Chang, MD, PhD, Natalia F. Callaway, MD, MS, Verena Steffen, MSc, Karl Csaky, MD, PhD, Robyn H. Guymer, MBBS, PhD, David G. Birch, PhD, Praveen J. Patel, MD, Michael Ip, MD, Simon S. Gao, PhD, Jayla Briggs, BS, Lee Honigberg, PhD, Phillip Lai, MD, Daniela Ferrara, MD, PhD, Yasir J. Sepah, MBBS
Publikováno v:
Ophthalmology Science, Vol 4, Iss 1, Pp 100351- (2024)
Purpose: To assess different microperimetry (MP) macular sensitivity outcome measures capturing functional deterioration in eyes with geographic atrophy (GA) secondary to age-related macular degeneration (AMD). Design: Patients were included from 2 i
Externí odkaz:
https://doaj.org/article/4cac05321aed4ed8bfcbc006faad2bbe
Publikováno v:
Ophthalmology Science, Vol 3, Iss 4, Pp 100301- (2023)
Purpose: To investigate the relationship between complement pathway activities and progression of geographic atrophy (GA) secondary to age-related macular degeneration in samples collected from patients enrolled in the Chroma and Spectri trials. Desi
Externí odkaz:
https://doaj.org/article/870ab318f19d404c9039bbeb0e5c46d3
Publikováno v:
Ophthalmology Science, Vol 3, Iss 3, Pp 100286- (2023)
Purpose: Lampalizumab, an antigen-binding fragment of a humanized monoclonal antibody directed against complement factor D (CFD), is designed to treat geographic atrophy (GA) secondary to age-related macular degeneration. Given the lack of clinical e
Externí odkaz:
https://doaj.org/article/77ee63aa587c4d2c901652e1beaa3098
Autor:
Sharon M. Rymut, Siddharth Sukumaran, Gizette Sperinde, Meire Bremer, Joshua Galanter, Kenta Yoshida, Jordan Smith, Prajna Banerjee, Viyia Sverkos, Fang Cai, Verena Steffen, Lindsay M. Henderson, Horace Rhee, Paula N. Belloni, Joseph H. Lin, Tracy L. Staton
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 2, Pp 451-463 (2022)
Abstract Tryptase is the most abundant secretory granule protein in human lung mast cells and plays an important role in asthma pathogenesis. MTPS9579A is a novel monoclonal antibody that selectively inhibits tryptase activity by dissociating active
Externí odkaz:
https://doaj.org/article/f7a4fbb6f2ef4fbb9936375d3e4e7d94
Autor:
Neha, Anegondi, Simon S, Gao, Verena, Steffen, Richard F, Spaide, SriniVas R, Sadda, Frank G, Holz, Christina, Rabe, Lee, Honigberg, Elizabeth M, Newton, Julia, Cluceru, Michael G, Kawczynski, Thomas, Bengtsson, Daniela, Ferrara, Qi, Yang
Publikováno v:
Ophthalmology Retina. 7:243-252
To develop deep learning models for annualized geographic atrophy (GA) growth rate prediction using fundus autofluorescence (FAF) images and spectral-domain OCT volumes from baseline visits, which can be used for prognostic covariate adjustment to in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::388c96da0a556148af7955c3ccaeab91
https://doi.org/10.1016/j.oret.2022.08.018
https://doi.org/10.1016/j.oret.2022.08.018
Autor:
Steffen Schmitz-Valckenberg, Marlene Saßmannshausen, Sarah Thiele, Simon S. Gao, Frank G. Holz, Martina Braun, Hao Chen, Daniela Ferrara, Lee Honigberg, Verena Steffen
Publikováno v:
Ophthalmologica. 244:523-534
Introduction: This retrospective analysis assessed geographic atrophy (GA) progression in fellow eyes from the Proxima B trial intermediate age-related macular degeneration (iAMD) subcohort using high-resolution multimodal imaging anchored on optical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7342d28858dcbb278ccee0cb7f25688e
https://doi.org/10.1159/000517881
https://doi.org/10.1159/000517881
Autor:
Qi Yang, Neha Anegondi, Verena Steffen, Simon S. Gao, Julia Cluceru, Christina Rabe, Jian Dai, Daniela Ferrara
Publikováno v:
Lecture Notes in Computer Science ISBN: 9783031177200
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::671391705696c2002d7893039fd7d819
https://doi.org/10.1007/978-3-031-17721-7_4
https://doi.org/10.1007/978-3-031-17721-7_4
Autor:
Beth L. Ostaszewski, Tobias Bittner, Verena Steffen, David Mengel, Dominic M. Walsh, Christina Rabe, Dennis J. Selkoe, Ting Yang, Yifan Dang
Publikováno v:
Annals of Neurology
Objective Oligomeric forms of amyloid β protein (oAβ) are believed to be principally responsible for neurotoxicity in Alzheimer disease (AD), but it is not known whether anti-Aβ antibodies are capable of lowering oAβ levels in humans. Methods We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c091c8359cdccc5f65630f09be234940
https://doi.org/10.1002/ana.25513
https://doi.org/10.1002/ana.25513
Publikováno v:
Multimodal Biomedical Imaging XVI.
Geographic atrophy (GA) is late-stage dry age-related macular degeneration (AMD). Improved predictors of GA progression would be useful in clinical trial design and may be relevant for clinical practice. The purpose of this study was to accurately pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03baf5aa4abbcb70f43ba7fa242da0e8
https://doi.org/10.1117/12.2575898
https://doi.org/10.1117/12.2575898