Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Verena, Ruprecht"'
Autor:
Ishier Raote, Ann-Helen Rosendahl, Hanna-Maria Häkkinen, Carina Vibe, Ismail Küçükaylak, Mugdha Sawant, Lena Keufgens, Pia Frommelt, Kai Halwas, Katrina Broadbent, Marina Cunquero, Gustavo Castro, Marie Villemeur, Julian Nüchel, Anna Bornikoel, Binita Dam, Ravindra K. Zirmire, Ravi Kiran, Carlo Carolis, Jordi Andilla, Pablo Loza-Alvarez, Verena Ruprecht, Colin Jamora, Felix Campelo, Marcus Krüger, Matthias Hammerschmidt, Beate Eckes, Ines Neundorf, Thomas Krieg, Vivek Malhotra
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Uncontrolled secretion of ECM proteins, such as collagen, can lead to excessive scarring and fibrosis and compromise tissue function. Despite the widespread occurrence of fibrotic diseases and scarring, effective therapies are lacking. A pro
Externí odkaz:
https://doaj.org/article/252118aa60de4fe1a96942bcae197b43
Autor:
Sefora Conti, Valeria Venturini, Adrià Cañellas-Socias, Carme Cortina, Juan F. Abenza, Camille Stephan-Otto Attolini, Emily Middendorp Guerra, Catherine K. Xu, Jia Hui Li, Leone Rossetti, Giorgio Stassi, Pere Roca-Cusachs, Alba Diz-Muñoz, Verena Ruprecht, Jochen Guck, Eduard Batlle, Anna Labernadie, Xavier Trepat
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Colorectal cancer (CRC) tumors are composed of heterogeneous and plastic cell populations, including a pool of cancer stem cells that express LGR5. Whether these distinct cell populations display different mechanical properties, and how thes
Externí odkaz:
https://doaj.org/article/f3eda4b90df041b09e2517b0f47ce22e
Autor:
Luis Felipe Morales-Curiel, Adriana Carolina Gonzalez, Gustavo Castro-Olvera, Li-Chun (Lynn) Lin, Malak El-Quessny, Montserrat Porta-de-la-Riva, Jacqueline Severino, Laura Battle Morera, Valeria Venturini, Verena Ruprecht, Diego Ramallo, Pablo Loza-Alvarez, Michael Krieg
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Bioluminescence microscopy with deep learning enables subsecond exposures for timelapse and volumetric imaging with denoising and yields high signal-to-noise ratio images of cells.
Externí odkaz:
https://doaj.org/article/e61eac0cada44b279384c4020b8a7dd9
Autor:
Ivan Zadra, Senda Jimenez-Delgado, Miquel Anglada-Girotto, Carolina Segura-Morales, Zachary J. Compton, Carsten Janke, Luis Serrano, Verena Ruprecht, Isabelle Vernos
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The authors show that polyglutamylation of spindle microtubules is essential for error-free chromosome segregation and is mediated through Tubulin Tyrosine Ligase Like 11 (TTLL11), which is found to be frequently downregulated in cancer.
Externí odkaz:
https://doaj.org/article/c59e82c185544651a5ca231bbf2ff9fa
Autor:
Keisuke Sako, Saurabh J. Pradhan, Vanessa Barone, Álvaro Inglés-Prieto, Patrick Müller, Verena Ruprecht, Daniel Čapek, Sanjeev Galande, Harald Janovjak, Carl-Philipp Heisenberg
Publikováno v:
Cell Reports, Vol 16, Iss 3, Pp 866-877 (2016)
During metazoan development, the temporal pattern of morphogen signaling is critical for organizing cell fates in space and time. Yet, tools for temporally controlling morphogen signaling within the embryo are still scarce. Here, we developed a photo
Externí odkaz:
https://doaj.org/article/844fc9840afe40f88c9c4914fbd0d71c
Autor:
Ludovica, Ciampi, Federica, Mantica, Laura, López-Blanch, Jon, Permanyer, Cristina, Rodriguez-Marín, Jingjing, Zang, Damiano, Cianferoni, Senda, Jiménez-Delgado, Sophie, Bonnal, Samuel, Miravet-Verde, Verena, Ruprecht, Stephan C F, Neuhauss, Sandro, Banfi, Sabrina, Carrella, Luis, Serrano, Sarah A, Head, Manuel, Irimia
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(29)
Retinal photoreceptors have a distinct transcriptomic profile compared to other neuronal subtypes, likely reflecting their unique cellular morphology and function in the detection of light stimuli by way of the ciliary outer segment. We discovered a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::20d26c4067477c5ebe55c3d0389c5599
https://pubmed.ncbi.nlm.nih.gov/35858306
https://pubmed.ncbi.nlm.nih.gov/35858306
Autor:
Juan Manuel García-Arcos, Johannes Ziegler, Silvia Grigolon, Loïc Reymond, Gaurav Shajepal, Cédric J. Cattin, Alexis Lomakin, Daniel Müller, Verena Ruprecht, Stefan Wieser, Raphael Voituriez, Matthieu Piel
Spontaneous locomotion is a common feature of most metazoan cells, generally attributed to the fundamental properties of the actomyosin network. This force-producing machinery has been studied down to the most minute molecular details, especially in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5a58bcbb2a06e463b7bdab42393f5a9
https://doi.org/10.1101/2022.07.14.500109
https://doi.org/10.1101/2022.07.14.500109
Autor:
Luis Felipe Morales-Curiel, Gustavo Castro-Olvera, Adriana Gonzalez, Lynn Lin, Malak El-Quessny, Montserrat Porta-de-la-Riva, Jacqueline Severino, Laura Battle, Diego Ramallo, Verena Ruprecht, Pablo Loza-Alvarez, Michael Krieg
The application of genetically encoded fluorophores for microscopy has afforded one of the biggest revolutions in the biosciences. Bioluminescence microscopy is an appealing alternative to fluorescence microscopy, because it does not depend on extern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f27ddf9a0bec8fa8b617fa51436102c
https://doi.org/10.1101/2022.05.31.494105
https://doi.org/10.1101/2022.05.31.494105
Autor:
Marta Miret-Cuesta, Queralt Tolosa-Ramon, Hanna-Maria Häkkinen, Stefan Wieser, Senda Jiménez-Delgado, Christopher N. Wyatt, Manuel Irimia, Andrew Callan-Jones, Esteban Hoijman, Verena Ruprecht
Publikováno v:
Nature. 590:618-623
Errors in early embryogenesis are a cause of sporadic cell death and developmental failure1,2. Phagocytic activity has a central role in scavenging apoptotic cells in differentiated tissues3-6. However, how apoptotic cells are cleared in the blastula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372c4675449a8e306120cc16259f9635
https://doi.org/10.1038/s41586-021-03200-3
https://doi.org/10.1038/s41586-021-03200-3
Autor:
Ivan Zadra, Senda Jimenez-Delgado, Miquel Anglada-Girotto, Carolina Segura-Morales, Zachary J. Compton, Carsten Janke, Luis Serrano, Verena Ruprecht, Isabelle Vernos
Publikováno v:
Nature communications. 13(1)
Regulation of microtubule (MT) dynamics is key for mitotic spindle assembly and faithful chromosome segregation. Here we show that polyglutamylation, a still understudied post-translational modification of spindle MTs, is essential to define their dy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a0defaeebc30ba0e0a6c5992769e53e
https://pubmed.ncbi.nlm.nih.gov/36414642
https://pubmed.ncbi.nlm.nih.gov/36414642