Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Vered Solomon"'
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 69:695-699
Geobacillus stearothermophilus T-6 is a thermophilic soil bacterium that possesses an extensive system for the utilization of hemicellulose. The bacterium produces a small number of endo-acting extracellular enzymes that cleave high-molecular-weight
Autor:
Shifra, Lansky, Onit, Alalouf, Vered, Solomon, Anat, Alhassid, Lata, Govada, Naomi E, Chayen, Naomi E, Chayan, Hassan, Belrhali, Yuval, Shoham, Gil, Shoham
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 69:430-434
Acetylxylan esterases are part of the hemi-cellulolytic system of many microorganisms which utilize plant biomass for growth. Xylans, which are polymeric sugars that constitute a significant part of the plant biomass, are usually substituted with ace
Autor:
James Davis, William J. Boyle, Anthony W. Bannon, Vickie E. Baracos, David L. Lacey, Xiaolan Zhou, H.Q. Han, Vered Solomon, Keith Soo-Nyung Kwak
Publikováno v:
Cancer Research. 64:8193-8198
The progressive depletion of skeletal muscle is a hallmark of many types of advanced cancer and frequently is associated with debility, morbidity, and mortality. Muscle wasting is primarily mediated by the activation of the ubiquitin-proteasome syste
Publikováno v:
Proceedings of the National Academy of Sciences. 101:11275-11280
Relating thermodynamic parameters to structural and biochemical data allows a better understanding of substrate binding and its contribution to catalysis. The analysis of the binding of carbohydrates to proteins or enzymes is a special challenge beca
Autor:
Hagit Cohen, Jukka Mönkkönen, Eli Breuer, Taly Pinto, N. Patlas, Ivan S. Alferiev, Gerhard Hägele, Vered Solomon, Hilah Sagi, Markus J. Seibel, Aviva Ezra, David Stepensky, Asher Ornoy, Amnon Hoffman, Gershon Golomb
Publikováno v:
Pharmaceutical Research. 16:1399-1406
Purpose. To validate our hypothesis that a bisphosphonate (BP) having a nitrogen-containing heterocyclic ring on the side chain, and with no hydroxyl on the geminal carbon would possess increased activity, and better oral bioavailability due to enhan
Publikováno v:
The Journal of Nutrition. 129:227S-237S
Publikováno v:
Proceedings of the National Academy of Sciences. 95:12602-12607
The rapid loss of muscle mass that accompanies many disease states, such as cancer or sepsis, is primarily a result of increased protein breakdown in muscle, and several observations have suggested an activation of the ubiquitin–proteasome system.
Autor:
Asher Ornoy, N. Patlas, Ivan S. Alferiev, Gershon Golomb, Gerhard Hägele, Eli Breuer, Naomi Eidelman, Vered Solomon, Hagit Cohen
Publikováno v:
Pharmaceutical Research. 15:606-613
Purpose. This work was aimed at synthesizing novel bisphosphonates (BPs) and examining them in comparison to clinically used BPs such as pamidronate and alendronate, and to tetracycline, in order to evaluate their potential as anticalcification and a
Structure-specificity relationships of an intracellular xylanase from Geobacillus stearothermophilus
Publikováno v:
Acta crystallographica. Section D, Biological crystallography. 63(Pt 8)
Geobacillus stearothermophilus T-6 is a thermophilic Gram-positive bacterium that produces two selective family 10 xylanases which both take part in the complete degradation and utilization of the xylan polymer. The two xylanases exhibit significantl
Autor:
Martin L. Yarmush, Livingston Van De Water, Vered Solomon, Richard N. Mitchell, Sundararajan V Madibally, Mehmet Toner
Publikováno v:
The Journal of surgical research. 109(2)
Background. Insulin is proposed as a therapy for suppressing muscle wasting after burn trauma although the long-term effects of this therapy on wound healing are not yet known. The present study was designed to investigate the effect of systemically