Atheroma transcriptomics identifies ARNTL as a smooth muscle cell regulator and with clinical and genetic data improves risk stratification.

Autor: Narayanan S; Vascular Surgery, Department of Molecular Medicine and Surgery, Karolinska University Hospital and Karolinska Institutet, BioClinicum J8:20, Visionsgatan 4, SE-171 76 Stockholm, Sweden., Vuckovic S; Vascular Surgery, Department of Molecular Medicine and Surgery, Karolinska University Hospital and Karolinska Institutet, BioClinicum J8:20, Visionsgatan 4, SE-171 76 Stockholm, Sweden., Bergman O; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Karolinska University Hospital, Solna, Sweden., Wirka R; Department of Medicine and Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Verdezoto Mosquera J; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Chen QS; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Karolinska University Hospital, Solna, Sweden., Baldassarre D; Centro Cardiologico Monzino, IRCCS, Milan, Italy.; Department of Medical Biotechnology and Translational Medicine, Università di Milano, Milan, Italy., Tremoli E; Centro Cardiologico Monzino, IRCCS, Milan, Italy., Veglia F; Centro Cardiologico Monzino, IRCCS, Milan, Italy., Lengquist M; Vascular Surgery, Department of Molecular Medicine and Surgery, Karolinska University Hospital and Karolinska Institutet, BioClinicum J8:20, Visionsgatan 4, SE-171 76 Stockholm, Sweden., Aherahrrou R; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.; Institute for Cardiogenetics, Universität zu Lübeck; DZHK (German Centre for Cardiovascular Research), Partner Site Hamburg/Kiel/Lübeck, Germany.; University Heart Centre Lübeck, Lübeck, Germany., Razuvaev A; Vascular Surgery, Department of Molecular Medicine and Surgery, Karolinska University Hospital and Karolinska Institutet, BioClinicum J8:20, Visionsgatan 4, SE-171 76 Stockholm, Sweden., Gigante B; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Karolinska University Hospital, Solna, Sweden., Björck HM; Division of Cardiovascular Medicine, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Karolinska University Hospital, Solna, Sweden., Miller CL; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Quertermous T; Division of Cardiovascular Medicine, Stanford University, Stanford, CA, USA., Hedin U; Vascular Surgery, Department of Molecular Medicine and Surgery, Karolinska University Hospital and Karolinska Institutet, BioClinicum J8:20, Visionsgatan 4, SE-171 76 Stockholm, Sweden., Matic L; Vascular Surgery, Department of Molecular Medicine and Surgery, Karolinska University Hospital and Karolinska Institutet, BioClinicum J8:20, Visionsgatan 4, SE-171 76 Stockholm, Sweden.

Publikováno v: European heart journal [Eur Heart J] 2024 Nov 18. Date of Electronic Publication: 2024 Nov 18.