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CHIT1 at diagnosis predicts faster disability progression and reflects early microglial activation in multiple sclerosis.

Autor: Beliën J; Laboratory for Neuroimmunology, Department of Neurosciences, Leuven Brain Institute, KU Leuven, Leuven, Belgium., Swinnen S; Laboratory for Neuroimmunology, Department of Neurosciences, Leuven Brain Institute, KU Leuven, Leuven, Belgium.; Department of Neurology, University Hospitals Leuven, Leuven, Belgium., D'hondt R; Department of Public Health and Primary Care, KU Leuven, Kortrijk, Belgium.; Imec research group itec, KU Leuven, Kortrijk, Belgium., Verdú de Juan L; Department of Neuroimmunology, Center for Brain Research, Medical University of Vienna, Vienna, Austria., Dedoncker N; Laboratory for Neuroimmunology, Department of Neurosciences, Leuven Brain Institute, KU Leuven, Leuven, Belgium., Matthys P; Laboratory of Immunobiology, Department of Microbiology, Immunology and Transplantation, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium., Bauer J; Department of Neuroimmunology, Center for Brain Research, Medical University of Vienna, Vienna, Austria., Vens C; Department of Public Health and Primary Care, KU Leuven, Kortrijk, Belgium.; Imec research group itec, KU Leuven, Kortrijk, Belgium., Moylett S; Laboratory for Neuroimmunology, Department of Neurosciences, Leuven Brain Institute, KU Leuven, Leuven, Belgium., Dubois B; Laboratory for Neuroimmunology, Department of Neurosciences, Leuven Brain Institute, KU Leuven, Leuven, Belgium. benedicte.dubois@uzleuven.be.; Department of Neurology, University Hospitals Leuven, Leuven, Belgium. benedicte.dubois@uzleuven.be.

Publikováno v: Nature communications [Nat Commun] 2024 Jun 12; Vol. 15 (1), pp. 5013. Date of Electronic Publication: 2024 Jun 12.