Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Vera Vorstandlechner"'
Autor:
Vera Vorstandlechner, Maria Laggner, Dragan Copic, Katharina Klas, Martin Direder, Yiyan Chen, Bahar Golabi, Werner Haslik, Christine Radtke, Erwin Tschachler, Konrad Hötzenecker, Hendrik Jan Ankersmit, Michael Mildner
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Mechanisms triggering hypertrophic scar formation remain poorly understood. Here the authors perform scRNA-seq on mature human hypertrophic scars and developing scars in mice to identify the serine proteases dipeptidyl-peptidase 4 and urokinase as ke
Externí odkaz:
https://doaj.org/article/358e2696c34f432285e35a6424f017c0
Autor:
Maria Laggner, Gabriela Sánchez Acosta, Claudia Kitzmüller, Dragan Copic, Florian Gruber, Lukas Matthäus Altenburger, Vera Vorstandlechner, Alfred Gugerell, Martin Direder, Katharina Klas, Daniel Bormann, Anja Peterbauer, Akira Shibuya, Barbara Bohle, Hendrik Jan Ankersmit, Michael Mildner
Publikováno v:
EBioMedicine, Vol 81, Iss , Pp 104093- (2022)
Summary: Background: IgE-mediated hypersensitivity is becoming increasingly prevalent and activation of mast cells and basophils represent key events in the pathophysiology of allergy. We have previously reported that the secretome of γ-irradiated p
Externí odkaz:
https://doaj.org/article/bf8011a161ef4ab6abd6e073157238f0
Autor:
Vera Vorstandlechner, Dragan Copic, Katharina Klas, Martin Direder, Bahar Golabi, Christine Radtke, Hendrik J. Ankersmit, Michael Mildner
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1065 (2023)
Hypertrophic scars can cause pain, movement restrictions, and reduction in the quality of life. Despite numerous options to treat hypertrophic scarring, efficient therapies are still scarce, and cellular mechanisms are not well understood. Factors se
Externí odkaz:
https://doaj.org/article/22afc284dc52470589206699a963e104
Autor:
Maria Laggner, Alfred Gugerell, Christiane Bachmann, Helmut Hofbauer, Vera Vorstandlechner, Marcus Seibold, Ghazaleh Gouya Lechner, Anja Peterbauer, Sibylle Madlener, Svitlana Demyanets, Dirk Sorgenfrey, Tobias Ostler, Michael Erb, Michael Mildner, Hendrik Jan Ankersmit
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-16 (2020)
Abstract Background The recent concept of secretome-based tissue regeneration has profoundly altered the field of regenerative medicine and offers promising novel therapeutic options. In contrast to medicinal products with a single active substance,
Externí odkaz:
https://doaj.org/article/8510a4803f6c4c24aea52fe3a003070b
Autor:
Christopher Kremslehner, Anne Miller, Robert Nica, Ionela-Mariana Nagelreiter, Marie-Sophie Narzt, Bahar Golabi, Vera Vorstandlechner, Michael Mildner, Julia Lachner, Erwin Tschachler, Francesca Ferrara, Kristaps Klavins, Markus Schosserer, Johannes Grillari, Arvand Haschemi, Florian Gruber
Publikováno v:
Redox Biology, Vol 37, Iss , Pp 101583- (2020)
The epidermis is a multi-layered epithelium that consists mainly of keratinocytes which proliferate in its basal layer and then differentiate to form the stratum corneum, the skin's ultimate barrier to the environment. During differentiation keratino
Externí odkaz:
https://doaj.org/article/848b167f27eb4a08983cbf5b52fc64be
Autor:
Maria Laggner, Dragan Copic, Lucas Nemec, Vera Vorstandlechner, Alfred Gugerell, Florian Gruber, Anja Peterbauer, Hendrik J. Ankersmit, Michael Mildner
Publikováno v:
EBioMedicine, Vol 55, Iss , Pp - (2020)
Background: Since numerous pathological conditions are evoked by unwanted dendritic cell (DC) activity, therapeutic agents modulating DC functions are of great medical interest. In regenerative medicine, cellular secretomes have gained increasing att
Externí odkaz:
https://doaj.org/article/7302e099ba96449c9260b4f8457224e7
Autor:
Martin Direder, Tamara Weiss, Dragan Copic, Vera Vorstandlechner, Maria Laggner, Karin Pfisterer, Caterina Selina Mildner, Katharina Klas, Daniel Bormann, Werner Haslik, Christine Radtke, Matthias Farlik, Lisa Shaw, Bahar Golabi, Erwin Tschachler, Konrad Hoetzenecker, Hendrik Jan Ankersmit, Michael Mildner
Publikováno v:
Matrix Biology. 108:55-76
Keloids are disfiguring, hypertrophic scars with yet poorly understood pathomechanisms, which could lead to severe functional impairments. Here we analyzed the characteristics of keloidal cells by single cell sequencing and discovered the presence of
Autor:
Michael Mildner, Yiyan Chen, K. Hötzenecker, Erwin Tschachler, Katharina Klas, Maria Laggner, Hendrik Jan Ankersmit, Dragan Copic, Werner Haslik, Bahar Golabi, Martin Direder, Vera Vorstandlechner, Christine Radtke
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Nature Communications
Nature Communications
Despite recent advances in understanding skin scarring, mechanisms triggering hypertrophic scar formation are still poorly understood. In the present study, we investigate mature human hypertrophic scars and developing scars in mice at single cell re
Autor:
Michael Mildner, Hendrik Ankersmit, Daniel Bormann, Matthias Wielscher, Maria Laggner, Katharina Klas, Vera Vorstandlechner, Dragan Copic, Tamara Weiss, Martin Direder
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5fe0bb840d83147651f2ee9c4a66263
https://doi.org/10.26226/m.62fa00a9928e86001b4e84a8
https://doi.org/10.26226/m.62fa00a9928e86001b4e84a8
Autor:
Daniel Langthaler, Katharina Ebenberger, Vera Vorstandlechner, Jakob Nedomansky, G. Ihra, Thomas Rath, Anna Pittermann, Gabriela Muschitz, Alexandra Fochtmann-Frana, Christine Radtke
Publikováno v:
Wiener Klinische Wochenschrift
Summary Background As a consequence of improved survival rates after burn injury occupational reintegration of burn survivors has gained increasing significance. We aimed to develop a precise patient questionnaire as a tool to evaluate factors contri