Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Vera Simic"'
Autor:
Nancy Palechor-Ceron, Ewa Krawczyk, Aleksandra Dakic, Vera Simic, Hang Yuan, Jan Blancato, Weisheng Wang, Fleesie Hubbard, Yun-Ling Zheng, Hancai Dan, Scott Strome, Kevin Cullen, Bruce Davidson, John F. Deeken, Sujata Choudhury, Peter H. Ahn, Seema Agarwal, Xuexun Zhou, Richard Schlegel, Priscilla A. Furth, Chong-Xian Pan, Xuefeng Liu
Publikováno v:
Cells, Vol 8, Iss 11, p 1327 (2019)
Traditional cancer models including cell lines and animal models have limited applications in both basic and clinical cancer research. Genomics-based precision oncology only help 2−20% patients with solid cancer. Functional diagnostics and patient-
Externí odkaz:
https://doaj.org/article/34fd46c6c5844396b7c84756c117ab54
Autor:
Aibing Wang, Dan Zhou, Ewa Krawczyk, Tuanjie Li, Vera Simic, Jie Lu, Xuefeng Liu, Richard Schlegel, Hang Yuan
Publikováno v:
Journal of Medical Virology. 95
Autor:
Cynthia M. Simbulan-Rosenthal, Frank A. Suprynowicz, Nancy Palechor-Ceron, Vera Simic, Richard Schlegel, Dean S. Rosenthal, Aleksandra Dakic, Songtao Yu, Sujata Choudhury, Shuang Fang, Anirudh Gaur, Kyle A. DiVito, Xin Li, Xuefeng Liu
Publikováno v:
Oncotarget
// Aleksandra Dakic 1, 2 , Kyle DiVito 3 , Shuang Fang 1, 2 , Frank Suprynowicz 1, 2 , Anirudh Gaur 3 , Xin Li 4 , Nancy Palechor-Ceron 1, 2 , Vera Simic 1, 2 , Sujata Choudhury 1, 2 , Songtao Yu 1, 2 , Cynthia M. Simbulan-Rosenthal 3 , Dean Rosentha
Autor:
Christopher Albanese, Thomas N. Darling, Seema Agarwal, Anatoly Dritschilo, Nancy Palechor-Ceron, Rajesh L. Thangapazham, Sujata Choudhury, Scott H. Randell, Ewa Krawczyk, Richard Schlegel, Hang Yuan, Tung-Wei Hou, Jie Lu, Frank A. Suprynowicz, Yun-Ling Zheng, Praathibha Sripadhan, Bhaskar Kallakury, Vera Simic, Xuefeng Liu, Chen Chen, Olga A. Timofeeva, Aleksandra Dakic, Dean G. Tang
Publikováno v:
Nature protocols. 12(2)
Historically, it has been difficult to propagate cells in vitro that are derived directly from human tumors or healthy tissue. However, in vitro preclinical models are essential tools for both the study of basic cancer biology and the promotion of tr
Autor:
Tsion Z. Minas, Michael D. Johnson, Frank A. Suprynowicz, Aleksandra Dakic, Nancy Palechor-Ceron, Geeta Upadhyay, Christopher Albanese, Xuefeng Liu, Richard Schlegel, Vera Simic
Publikováno v:
The American Journal of Pathology. 183(6):1862-1870
Both feeder cells and Rho kinase inhibition are required for the conditional reprogramming and immortalization of human epithelial cells. In the present study, we demonstrated that the Rho kinase inhibitor Y-27632, significantly suppresses keratinocy
Autor:
Xuefeng Liu, Stephen W. Byers, Frank A. Suprynowicz, Yiyu Zhang, John Doorbar, Sawali R. Sudarshan, Yuhai Dai, Ziad J. Sahab, Vera Simic, Richard Schlegel, Christopher M. Kamonjoh, Alexander Kirilyuk
Publikováno v:
Journal of Virology. 86:9465-9473
The high-risk human papillomavirus type 16 (HPV-16) E5 protein (16E5) induces tumors in a transgenic mouse model and may contribute to early stages of cervical carcinogenesis. Although high-risk E5 expression is generally thought to be lost during th
Autor:
Jess D. Hebert, Vera Simic, Richard Schlegel, Ewa Krawczyk, Christopher M. Kamonjoh, Sawali R. Sudarshan, Frank A. Suprynowicz
Publikováno v:
Journal of Virology. 84:10619-10629
The human papillomavirus type 16 E5 oncoprotein (16E5) enhances acute, ligand-dependent activation of the epidermal growth factor receptor (EGFR) and concomitantly alkalinizes endosomes, presumably by binding to the 16-kDa “c” subunit of the V-AT
Publikováno v:
Virology. 332(1):102-113
The E5 proteins of bovine papillomavirus type 1 (BPV-1) and human papillomavirus type 16 (HPV-16) are small (44–83 amino acids), hydrophobic polypeptides that localize to membranes of the Golgi apparatus and endoplasmic reticulum, respectively. Whi
Autor:
Ewa Krawczyk, Frank A. Suprynowicz, Sujata Choudhury, Aleksandra Dakic, Richard Schlegel, Nancy Palechor-Ceron, Jie Lu, Vera Simic, Tung-Wei Hou, Hang Yuan, Praathibha Sripadhan, Seema Agarwal, Chen Chen, Xuefeng Liu
Publikováno v:
Cancer Research. 77:5777-5777
The E6/E7 oncogenes of the high-risk HPVs are both necessary and sufficient to immortalize HFKs and their presence and expression is required for the continued proliferation of HPV-positive cervical cancer cells. We and others have shown previously t
Autor:
Richard Schlegel, Ogla Timofeeva, Vera Simic, Xuefeng Liu, Ewa Krawczyk, Bhaskar Kallakury, Aleksandra Dakic, Nancy Palechor-Ceron, Anatoly Dritschilo
Publikováno v:
Cancer Research. 76:4256-4256
Background: Preclinical models provide an essential tool to study both cancer biology with particular relevance to identifying appropriate therapies and new targets. Both Patient-derived xenografts and 3D methods require significant time for the nece