Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Vera S. Efimova"'
Autor:
Isaeva Lv, L.A. Novikova, Marine E. Bozdaganyan, Philipp S. Orekhov, Mikhail A. Rubtsov, Vera S. Efimova
Publikováno v:
Journal of Biotechnology. 325:186-195
Cytochrome P450scc system performs the first rate-limiting stage of steroidogenesis in mammals. The bovine P450scc system was reconstructed in Saccharomyces cerevisiae, using a foot-and-mouth disease virus 2A peptide (F2A)-based construct, to co-expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f410aa35c79ed55badf3a42683d62c10
https://doi.org/10.1016/j.jbiotec.2020.10.028
https://doi.org/10.1016/j.jbiotec.2020.10.028
Autor:
Vera S, Efimova, Ludmila V, Isaeva, Philipp S, Orekhov, Marine E, Bozdaganyan, Mikhail A, Rubtsov, Ludmila A, Novikova
Publikováno v:
Journal of biotechnology. 325
Cytochrome P450scc system performs the first rate-limiting stage of steroidogenesis in mammals. The bovine P450scc system was reconstructed in Saccharomyces cerevisiae, using a foot-and-mouth disease virus 2A peptide (F2A)-based construct, to co-expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3067dcc15214fa7ef4f7e8bd220f53e0
https://pubmed.ncbi.nlm.nih.gov/33157198
https://pubmed.ncbi.nlm.nih.gov/33157198
Autor:
Vera S. Efimova, Vadim N. Tashlitsky, Anastasia Andreevna Labudina, Isaeva Lv, L.A. Novikova, Mikhail A. Rubtsov
Publikováno v:
Journal of Cellular Biochemistry. 120:3124-3136
The cholesterol hydroxylase/lyase (CHL) system, consisting of cytochrome P450scc, adrenodoxin (Adx) and adrenodoxin reductase (AdR), initiates mammalian steroidogenesis, converting cholesterol to pregnenolone. The foot-and-mouth disease virus 2A-base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf7ef3e6cf8921f6874864df005caac1
https://doi.org/10.1002/jcb.27577
https://doi.org/10.1002/jcb.27577
Publikováno v:
Molecular biotechnology. 61(4)
The cholesterol hydroxylase/lyase (CHL) system, located in the mitochondria of the mammalian adrenal cortex cells, consists of cytochrome P450scc (CYP11A1), adrenodoxin (Adx), and adrenodoxin reductase (AdR) and performs the first stage of the steroi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::874d2885fa5fc1d492f07d2b4c1330ac
https://pubmed.ncbi.nlm.nih.gov/30729436
https://pubmed.ncbi.nlm.nih.gov/30729436
Autor:
L.A. Novikova, Nikolai N. Sluchanko, Mikhail A. Rubtsov, N. S. Frolova, Y. V. Faletrov, Vladimir M. Shkumatov, Kristina V. Tugaeva, Matvey S. Horetski, Isaeva Lv, Vera S. Efimova, Quingquing Lin
Publikováno v:
Chemistry and Physics of Lipids. 227:104850
20-hydroxycholesterol is a signaling oxysterol with immunomodulating functions and, thus, structural analogues with reporter capabilities could be useful for studying and modulating the cellular processes concerned. We have synthesized three new 20-h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15aa15e2a962998c09c17b07121cd0de
https://doi.org/10.1016/j.chemphyslip.2019.104850
https://doi.org/10.1016/j.chemphyslip.2019.104850
Autor:
Vera S. Efimova, Bakhyt T. Matkarimov, Anna V. Glyakina, Mikhail V. Karpov, Isaeva Lv, L.A. Novikova, Mikhail A. Rubtsov, Nikita V. Dovidchenko, Oxana V. Galzitskaya, Marina V. Donova, Nicolai Strizhov
Publikováno v:
Steroids. 143
Cytochrome P450scc (CYP11A1) is a mammalian mitochondrial enzyme which catalyzes cholesterol side chain cleavage to form pregnenolone. Along with cholesterol, some other steroids including sterols with a branched side chain like β-sitosterol are the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db8f271d6e6ecaa0db9a247dd2f7f5f
https://pubmed.ncbi.nlm.nih.gov/30641046
https://pubmed.ncbi.nlm.nih.gov/30641046
Publikováno v:
Molecular biotechnology. 59(9-10)
2A peptide discovered in Picornaviridae is capable of self-cleavage providing an opportunity to carry out synthesis of several proteins using one transcript. Dissociation in the 2A sequence during translation leads to the individual proteins formatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d90c9a6983a1a541b338a0caf241bd1b
https://pubmed.ncbi.nlm.nih.gov/28799023
https://pubmed.ncbi.nlm.nih.gov/28799023