Zobrazeno 1 - 10 of 29 pro vyhledávání: '"Vera Pütter"'
1
Akademický článek
Dual targeting of the androgen receptor and PI3K/AKT/mTOR pathways in prostate cancer models improves antitumor efficacy and promotes cell apoptosis
Autor: Tatsuo Sugawara, Ekaterina Nevedomskaya, Simon Heller, Annika Böhme, Ralf Lesche, Oliver vonAhsen, Sylvia Grünewald, Holly M. Nguyen, Eva Corey, Simon J. Baumgart, Victoria Georgi, Vera Pütter, Amaury Fernández‐Montalván, James D. Vasta, Matthew B. Robers, Oliver Politz, Dominik Mumberg, Bernard Haendler
Publikováno v: Molecular Oncology, Vol 18, Iss 3, Pp 726-742 (2024)
Prostate cancer is a frequent malignancy in older men and has a very high 5‐year survival rate if diagnosed early. The prognosis is much less promising if the tumor has already spread outside the prostate gland. Targeted treatments mainly aim at bl
Externí odkaz: https://doaj.org/article/d4cfe16cad13404788f8437fa5048036
Zobrazit plný text záznamu
3
Akademický článek
Expression and Characterization of Relaxin Family Peptide Receptor 1 Variants
Autor: David Speck, Gunnar Kleinau, Mark Meininghaus, Antje Erbe, Alexandra Einfeldt, Michal Szczepek, Patrick Scheerer, Vera Pütter
Publikováno v: Frontiers in Pharmacology, Vol 12 (2022)
G-protein coupled receptors (GPCR) transduce extracellular stimuli into the cell interior and are thus centrally involved in almost all physiological-neuronal processes. This essential function and association with many diseases or pathological condi
Externí odkaz: https://doaj.org/article/a28adbaf73874fac9aa49bdca5b38ca8
Zobrazit plný text záznamu
4
Akademický článek
Discovery of novel MDR-Mycobacterium tuberculosis inhibitor by new FRIGATE computational screen.
Autor: Christoph Scheich, Zoltán Szabadka, Beáta Vértessy, Vera Pütter, Vince Grolmusz, Markus Schade
Publikováno v: PLoS ONE, Vol 6, Iss 12, p e28428 (2011)
With 1.6 million casualties annually and 2 billion people being infected, tuberculosis is still one of the most pressing healthcare challenges. Here we report on the new computational docking algorithm FRIGATE which unites continuous local optimizati
Externí odkaz: https://doaj.org/article/a878c5b6708143229ed51b0cd2d747ea
Zobrazit plný text záznamu
5
Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists
Autor: Douglas L, Orsi, Elisabeth, Pook, Nico, Bräuer, Anders, Friberg, Philip, Lienau, Christopher T, Lemke, Timo, Stellfeld, Ulf, Brüggemeier, Vera, Pütter, Hanna, Meyer, Maria, Baco, Stephanie, Tang, Andrew D, Cherniack, Lindsay, Westlake, Samantha A, Bender, Mustafa, Kocak, Craig A, Strathdee, Matthew, Meyerson, Knut, Eis, Jonathan T, Goldstein
Publikováno v: Journal of medicinal chemistry. 65(21)
The ligand-activated nuclear receptor peroxisome-proliferator-activated receptor-γ (PPARG or PPARγ) represents a potential target for a new generation of cancer therapeutics, especially in muscle-invasive luminal bladder cancer where PPARγ is a cr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ae813451ab4026cd308dc1142c4ed2b6
https://pubmed.ncbi.nlm.nih.gov/36542814
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje