Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Vera Pendino"'
Autor:
Megan J. Bywater, Deborah L. Burkhart, Jasmin Straube, Arianna Sabò, Vera Pendino, James E. Hudson, Gregory A. Quaife-Ryan, Enzo R. Porrello, James Rae, Robert G. Parton, Theresia R. Kress, Bruno Amati, Trevor D. Littlewood, Gerard I. Evan, Catherine H. Wilson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Levels of the transcription factor Myc are deregulated in a range of different cancers. Here the authors show that Myc induces rapid transcriptional responses in some mouse tissues (liver), but not others (heart), and that transcriptional and prolife
Externí odkaz:
https://doaj.org/article/6242a1a22a8f47f48a5d16c07381d895
Autor:
Marco J. Morelli, Gianni Paolo Gamarra Figueroa, Diego Pasini, Giorgia Ceccotti, Fulvio Chiacchiera, Nina Tanaskovic, Francesca Biagioni, Marco Filipuzzi, Arianna Sabò, Giulia Brumana, Mirko Doni, Andrea Bisso, Vera Pendino, Daniela Olivero, Bruno Amati, Stefano Campaner
Publikováno v:
Hepatology. 72:1430-1443
Background & AimsActivation of MYC and CTNNB1 (encoding β-catenin) can co-occur in liver cancer, but how these oncogenes cooperate in tumorigenesis remains unclear.Approach & ResultsWe generated a mouse model allowing conditional activation of MYC a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e85cf67ac24324babcc75cbaaad032a
https://doi.org/10.1002/hep.31120
https://doi.org/10.1002/hep.31120
Autor:
James E. Hudson, Arianna Sabò, James Rae, Gerard I. Evan, Deborah L. Burkhart, Bruno Amati, Robert G. Parton, Vera Pendino, Catherine H. Wilson, Megan Bywater, Enzo R. Porrello, Theresia R. Kress, Trevor D. Littlewood, Jasmin Straube, Gregory A. Quaife-Ryan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications
Nature Communications
It is unclear why some tissues are refractory to the mitogenic effects of the oncogene Myc. Here we show that Myc activation induces rapid transcriptional responses followed by proliferation in some, but not all, organs. Despite such disparities in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94985bdce6d77e286a080a18857a8c4d
https://doaj.org/article/6242a1a22a8f47f48a5d16c07381d895
https://doaj.org/article/6242a1a22a8f47f48a5d16c07381d895
Autor:
Catherine H. Wilson, Vera Pendino, James E. Hudson, Deborah L. Burkhart, Jasmin Straube, Megan Bywater, Arianna Sabò, Gregory A. Quaife-Ryan, Enzo R. Porrello, Gerard I. Evan, Theresia R. Kress, Bruno Amati, Trevor D. Littlewood
Publikováno v:
Circulation Research. 125
It is unclear why some tissues are refractory to the mitogenic effects of the pleiotropic transcription factor Myc, even when its expression is deregulated. We have developed an in vivo model permitting determination of the early transcriptional cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::920566b1a85772d64222a99b12c877fb
https://doi.org/10.1161/res.125.suppl_1.108
https://doi.org/10.1161/res.125.suppl_1.108
Publikováno v:
Nucleic Acids Research
The identification of a constantly increasing number of genes whose mutations are causally implicated in tumor initiation and progression (cancer genes) requires the development of tools to store and analyze them. The Network of Cancer Genes (NCG 3.0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2141c1a52719267c3827e08c9c35e327
http://europepmc.org/articles/PMC3245144
http://europepmc.org/articles/PMC3245144
Autor:
Vera Pendino, Matteo D’Antonio, Marco Gentilini, Emanuele Ratti, Francesca D. Ciccarelli, Omer An
Publikováno v:
Database: The Journal of Biological Databases and Curation
NCG 4.0 is the latest update of the Network of Cancer Genes, a web-based repository of systems-level properties of cancer genes. In its current version, the database collects information on 537 known (i.e. experimentally supported) and 1463 candidate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5f55011d0d8c1f291fbca0bf106f213
http://europepmc.org/articles/PMC3948431
http://europepmc.org/articles/PMC3948431