Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Vera Mugoni"'
Autor:
Vera Mugoni, Yari Ciani, Orsetta Quaini, Simone Tomasini, Michela Notarangelo, Federico Vannuccini, Alessia Marinelli, Elena Leonardi, Stefano Pontalti, Angela Martinelli, Daniele Rossetto, Isabella Pesce, Sheref S. Mansy, Mattia Barbareschi, Antonella Ferro, Orazio Caffo, Gerhardt Attard, Dolores Di Vizio, Vito Giuseppe D'Agostino, Caterina Nardella, Francesca Demichelis
Publikováno v:
Journal of Extracellular Biology, Vol 2, Iss 9, Pp n/a-n/a (2023)
Abstract Multi‐analyte liquid biopsies represent an emerging opportunity for non‐invasive cancer assessment. We developed ONCE (One Aliquot for Circulating Elements), an approach for the isolation of extracellular vesicles (EV) and cell‐free DN
Externí odkaz:
https://doaj.org/article/4ec0396d0d6d4b53b34bf42dcddc3061
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21908 (2011)
The lysosomal aspartic protease Cathepsin D (CD) is ubiquitously expressed in eukaryotic organisms. CD activity is essential to accomplish the acid-dependent extensive or partial proteolysis of protein substrates within endosomal and lysosomal compar
Externí odkaz:
https://doaj.org/article/9eb62298ae3c4d07a0f779cc3724009f
Publikováno v:
Cancer Letters. 524:57-69
Growing bodies of evidence have demonstrated that the identification of prostate cancer (PCa) biomarkers in the patients' blood and urine may remarkably improve PCa diagnosis and progression monitoring. Among diverse cancer-derived circulating materi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524614c979d893547bd030ebfc97d784
https://doi.org/10.1016/j.canlet.2021.10.011
https://doi.org/10.1016/j.canlet.2021.10.011
Autor:
Ming Chen, Riccardo Panella, Jonathan D. Lee, Jlenia Guarnerio, Francesco Lo-Coco, Richard Stone, Manoj Bhasin, Olga Pozdnyakova, Jon C. Aster, Lourdes M. Mendez, Ilene Galinsky, Letizia Longo, John G. Clohessy, Giulia Cheloni, Archita Venugopal Menon, José Cervera Zamora, David Avigan, Dina Stroopinsky, Vera Mugoni, Emanuele Monteleone, Pier Paolo Pandolfi, Andrew A. Lane
Publikováno v:
Cell Res
CELL RESEARCH
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
CELL RESEARCH
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Although targeted therapies have proven effective and even curative in human leukaemia, resistance often ensues. IDH enzymes are mutated in similar to 20% of human AML, with targeted therapies under clinical evaluation. We here characterize leukaemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e3e06a7e4d171856898a23b187f16c
https://europepmc.org/articles/PMC6796925/
https://europepmc.org/articles/PMC6796925/
Autor:
Caterina Nardella, Vera Mugoni, Francesca Demichelis, Antonella Ferro, Vito Giuseppe D'Agostino, Orazio Caffo, Michela Notarangelo, Orsetta Quaini, Yari Ciani
Publikováno v:
Clinical Cancer Research. 26:B60-B60
The last few years have witnessed exceptional advances in liquid biopsies based on the isolation and analysis of diverse tumor-derived material circulating in the blood, such as cell-free DNA (cfDNA) and extracellular vesicles (EVs). However, the iso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8aca12d1dc0bc318f43720055286558f
https://doi.org/10.1158/1557-3265.liqbiop20-b60
https://doi.org/10.1158/1557-3265.liqbiop20-b60
Publikováno v:
Journal of Chromatography A. 1412:59-66
The analysis of lipid molecules in living organism is an important step in deciphering metabolic pathways. Recently, the zebrafish has been adopted as a valuable animal model system to perform in vivo metabolomics studies, however limited methodologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169fe13227a934673f88750ff9bbb763
https://doi.org/10.1016/j.chroma.2015.07.115
https://doi.org/10.1016/j.chroma.2015.07.115
Publikováno v:
Nature Protocols. 8:2337-2347
Metabolism has a decisive role in many fundamental biological processes, including organism development and tissue homeostasis. Here we describe a protocol for fast and reliable (13)C-isotope-based in vivo metabolic profiling. This protocol covers th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a925855933706c33b60eca5ffd32040
https://doi.org/10.1038/nprot.2013.139
https://doi.org/10.1038/nprot.2013.139
Autor:
Vera Mugoni, Massimo Santoro, Valeria Catanzaro, Lorenzo Silengo, Claudio Medana, Emilia Turco, Jeroen Bakkers, Giuseppe Digilio, Ruben Postel, Michael P. Murphy, Elisa De Luca, Didier Y.R. Stainier
Publikováno v:
Cell
Cell, 152(3), 504-518. Elsevier B.V.
Cell, 152(3), 504-518. Elsevier B.V.
Summary Protection against oxidative damage caused by excessive reactive oxygen species (ROS) by an antioxidant network is essential for the health of tissues, especially in the cardiovascular system. Here, we identified a gene with important antioxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f79f8f8976df8681cff48999910ff68
Publikováno v:
Angiogenesis and Vascularisation ISBN: 9783709114278
The process of de novo vessel formation, called angiogenesis, is essential for tumor progression and metastasis. The identification and targeting of the molecular pathways involved in this process are becoming critical issues for anti-angiogenic canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::836939f6a347cddbdc779a68efceb937
http://hdl.handle.net/2318/147846
http://hdl.handle.net/2318/147846
High levels of reactive oxygen species (ROS) may cause a change of cellular redox state towards oxidative stress condition. This situation causes oxidation of molecules (lipid, DNA, protein) and leads to cell death. Oxidative stress also impacts the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dce8cc63b2030798e37f936487e5194
http://hdl.handle.net/2318/1505690
http://hdl.handle.net/2318/1505690