Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Vera Miranda"'
Autor:
Nair Lopes, Sofia Salta, Bianca Troncarelli Flores, Vera Miranda-Gonçalves, Margareta P. Correia, Davide Gigliano, Rita Guimarães, Rui Henrique, Carmen Jerónimo
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Background Oesophageal cancer remains a challenging disease with high mortality rates and few therapeutic options. In view of these difficulties, epigenetic drugs have emerged as potential alternatives for patient care. The goal of this stud
Externí odkaz:
https://doaj.org/article/a6e805f969c24f529614687cebfbde21
Autor:
Catarina Macedo-Silva, Vera Miranda-Gonçalves, Nuno Tiago Tavares, Daniela Barros-Silva, Joana Lencart, João Lobo, Ângelo Oliveira, Margareta P. Correia, Lucia Altucci, Carmen Jerónimo
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-13 (2023)
Abstract External beam radiotherapy (RT) is a leading first-line therapy for prostate cancer (PCa), and, in recent years, significant advances have been accomplished. However, RT resistance can arise and result in long-term recurrence or disease prog
Externí odkaz:
https://doaj.org/article/65286e906b2b4ab4ae73151352e131b7
Autor:
Catarina Macedo‐Silva, Vera Constâncio, Vera Miranda‐Gonçalves, Pedro Leite‐Silva, Sofia Salta, João Lobo, Rita Guimarães, Carina Carvalho‐Maia, Davide Gigliano, Mónica Farinha, Olga Sousa, Rui Henrique, Carmen Jerónimo
Publikováno v:
Cancer Medicine, Vol 12, Iss 7, Pp 8777-8788 (2023)
Abstract Background Esophageal cancer (ECa) is associated with high mortality, mostly due to late diagnosis, precluding curativeintent surgery. Hence, neoadjuvant chemoradiation (ChRT) is recommended in most patients regardless of histological subtyp
Externí odkaz:
https://doaj.org/article/d970b954e26b4a219791784a6f9bb2cf
Autor:
Florian A. Büttner, Stefan Winter, Viktoria Stühler, Steffen Rausch, Jörg Hennenlotter, Susanne Füssel, Stefan Zastrow, Matthias Meinhardt, Marieta Toma, Carmen Jerónimo, Rui Henrique, Vera Miranda-Gonçalves, Nils Kröger, Silvia Ribback, Arndt Hartmann, Abbas Agaimy, Christine Stöhr, Iris Polifka, Falko Fend, Marcus Scharpf, Eva Comperat, Gabriel Wasinger, Holger Moch, Arnulf Stenzl, Marco Gerlinger, Jens Bedke, Matthias Schwab, Elke Schaeffeler
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-19 (2022)
Abstract Background Renal cell carcinoma (RCC) is a heterogeneous disease comprising histologically defined subtypes. For therapy selection, precise subtype identification and individualized prognosis are mandatory, but currently limited. Our aim was
Externí odkaz:
https://doaj.org/article/876bc134c9284335b9606279982c1274
Autor:
Eduarda P. Martins, Céline S. Gonçalves, Marta Pojo, Rita Carvalho, Ana S. Ribeiro, Vera Miranda‐Gonçalves, Ricardo Taipa, Fernando Pardal, Afonso A. Pinto, Carlos Custódia, Cláudia C. Faria, Fátima Baltazar, Nuno Sousa, Joana Paredes, Bruno M. Costa
Publikováno v:
Molecular Oncology, Vol 16, Iss 14, Pp 2611-2631 (2022)
Glioblastoma (GBM) is the most common and malignant primary brain tumor in adults. The prognosis of patients is very poor, with a median overall survival of ~ 15 months after diagnosis. Cadherin‐3 (also known as P‐cadherin), a cell–cell adhesio
Externí odkaz:
https://doaj.org/article/226b5a08c45b46729dda3b5a0bc6f9c5
Autor:
Catarina Guimarães‐Teixeira, João Lobo, Vera Miranda‐Gonçalves, Daniela Barros‐Silva, Cláudia Martins‐Lima, Sara Monteiro‐Reis, José Pedro Sequeira, Isa Carneiro, Margareta P. Correia, Rui Henrique, Carmen Jerónimo
Publikováno v:
Molecular Oncology, Vol 16, Iss 9, Pp 1841-1856 (2022)
N6‐methyladenosine (m6A) and its regulatory proteins have been associated with tumorigenesis in several cancer types. However, knowledge on the mechanistic network related to m6A in bladder cancer (BlCa) is rather limited, requiring further investi
Externí odkaz:
https://doaj.org/article/614cd03d082a4bc982fc53e7b4347ae2
Publikováno v:
International Journal of Translational Medicine, Vol 2, Iss 2, Pp 134-147 (2022)
Protein aggregation is a common characteristic of several human diseases such as Alzheimer’s disease. Recent evidence has indicated that the aggregation of peptides such as p53 is also marked in cancer cells. The aim of this study was to correlate
Externí odkaz:
https://doaj.org/article/cdfbe70aea4b4b9b83a8ca0c89cf721a
Autor:
Vera Miranda-Gonçalves, João Lobo, Catarina Guimarães-Teixeira, Daniela Barros-Silva, Rita Guimarães, Mariana Cantante, Isaac Braga, Joaquina Maurício, Christoph Oing, Friedemann Honecker, Daniel Nettersheim, Leendert H. J. Looijenga, Rui Henrique, Carmen Jerónimo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-18 (2021)
Abstract Background Germ cell tumors (GCTs) are developmental cancers, tightly linked to embryogenesis and germ cell development. The recent and expanding field of RNA modifications is being increasingly implicated in such molecular events, as well a
Externí odkaz:
https://doaj.org/article/a7363cbfa25843038c4292ef51b2d603
Publikováno v:
Epigenetics, Vol 16, Iss 4, Pp 353-372 (2021)
Testicular germ cell tumours (TGCTs) are heterogeneous neoplasms mostly affecting young-adult men. Despite high survival rates, some patients with disseminated disease acquire cisplatin resistance, entailing the need for less toxic therapies. Epigene
Externí odkaz:
https://doaj.org/article/c2fab5c2b4ce4fedabbdef92ccd5fcda
Autor:
João Lobo, Vera Constâncio, Catarina Guimarães‐Teixeira, Pedro Leite‐Silva, Vera Miranda‐Gonçalves, José Pedro Sequeira, Laura Pistoni, Rita Guimarães, Mariana Cantante, Isaac Braga, Joaquina Maurício, Leendert H. J. Looijenga, Rui Henrique, Carmen Jerónimo
Publikováno v:
Molecular Oncology, Vol 15, Iss 4, Pp 846-865 (2021)
Testicular germ cell tumors (TGCTs) are the most common cancers in men aged 15–39 years and are divided into two major groups, seminomas and nonseminomas. Novel treatment options are required for these patients, to limit side effects of chemotherap
Externí odkaz:
https://doaj.org/article/52fde9c1694a4ab4be5da24a6b2b8d6b