Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Vera M. S. Isca"'
Autor:
Vera M. S. Isca, Gabrielle Bangay, Salvatore Princiotto, Lucília Saraíva, Daniel J. V. A. dos Santos, Alfonso T. García-Sosa, Patrícia Rijo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Protein kinase C is a family of kinases that play important roles in carcinogenesis. Medicinal plants from Plectranthus spp. (Lamiaceae) are a well-known source of interesting abietanes, such as 7α-acetoxy-6β-hydroxyroyleanone (Roy). This
Externí odkaz:
https://doaj.org/article/bb2ce814416a4a93a98fc9bfbad18360
Autor:
Márcia S. Filipe, Eva M. Domínguez-Martín, Tânia C. S. P. Pires, Tiane C. Finimundy, Bruno Melgar, Filipa Mandim, Vera M. S. Isca, Raquel Pereira, Silvia Teixidó-Trujillo, Natalia A. Capote, Milan Nikolić, Nenad Filipović, Ana M. Díaz-Lanza, Ana Cristina Figueiredo, Lillian Barros, Patrícia Rijo
Publikováno v:
ACS Omega, Vol 9, Iss 16, Pp 18113-18118 (2024)
Externí odkaz:
https://doaj.org/article/09198ab9e7784eeda8804c530fcacc91
Publikováno v:
Physiological Reports, Vol 12, Iss 5, Pp n/a-n/a (2024)
Abstract The future of physiology has been a recurrent concern for physiologists and Physiological Societies within post‐Bologna Europe and the European Higher Education Area (EHEA). Our paper provides an overview of Physiology teaching and researc
Externí odkaz:
https://doaj.org/article/661eabb9c4da401daf6a178aba2bee36
Autor:
Patricia Rijo, Tamer M. M. Abuamara, Lashin Saad Ali Lashin, Sherif A. Kamar, Vera M. S. Isca, Tahseen S. Mohammed, Mohamed S. M. Abdrabo, Mohamed A. Amin, Ahmed I. Abd El Maksoud, Amr Hassan
Publikováno v:
Pharmaceuticals, Vol 17, Iss 5, p 589 (2024)
Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA) are classified as high-risk infections that can lead to death, particularly among older individuals. Nowadays, plant nanoparticles such as glycyrrhizic acid are recognized a
Externí odkaz:
https://doaj.org/article/4c5defe08b004cf09fa459fea079a4b7
Autor:
Vera M. S. Isca, Przemysław Sitarek, Anna Merecz-Sadowska, Magdalena Małecka, Monika Owczarek, Joanna Wieczfińska, Radosław Zajdel, Paweł Nowak, Patricia Rijo, Tomasz Kowalczyk
Publikováno v:
Molecules, Vol 29, Iss 8, p 1807 (2024)
The abietane diterpenoid 7α-acetoxy-6β-hydroxyroyleanone (Roy) isolated from Plectranthus grandidentatus demonstrates cytotoxicity across numerous cancer cell lines. To potentiate anticancer attributes, a series of semi-synthetic Roy derivatives we
Externí odkaz:
https://doaj.org/article/ca6cc14bfa5649288219b0f8d5e9fb4e
Autor:
Gabrielle Bangay, Vera M. S. Isca, Daniel J. V. A. Dos Santos, Ricardo J. Ferreira, Salvatore Princiotto, Mirna Jovanovic, Milica Pesic, Patricia Rijo
Publikováno v:
Medical Sciences Forum, Vol 14, Iss 1, p 144 (2022)
The number of multidrug resistant (MDR) cancer cases across the globe is continuing to rise, such that the search for novel anti-cancer therapeutics is paramount. For instance, the overexpression of membrane transport proteins, such as P-glycoprotein
Externí odkaz:
https://doaj.org/article/9b2a6d2d23a74118b2312c6e8664c92f
Autor:
Catarina Garcia, Vera M. S. Isca, Filipe Pereira, Carlos M. Monteiro, Epole Ntungwe, Francisco Sousa, Jelena Dinic, Suvi Holmstedt, Amílcar Roberto, Ana Díaz-Lanza, Catarina P. Reis, Milica Pesic, Nuno R. Candeias, Ricardo J. Ferreira, Noélia Duarte, Carlos A. M. Afonso, Patrícia Rijo
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Cancer is among the leading causes of death worldwide. One of the most challenging obstacles in cancer treatment is multidrug resistance (MDR). Overexpression of P-glycoprotein (P-gp) is associated with MDR. The growing incidence of cancer and the de
Externí odkaz:
https://doaj.org/article/e0c57d17a6814473b2b968463276ad86
Autor:
Tomasz Kowalczyk, Anna Merecz-Sadowska, Patricia Rijo, Vera M. S. Isca, Laurent Picot, Marzena Wielanek, Tomasz Śliwiński, Przemysław Sitarek
Publikováno v:
Cells, Vol 10, Iss 5, p 1242 (2021)
According to the present knowledge, this is the first report on establishing transformed root cultures of Leonotis nepetifolia after Rhizobium rhizogenes-mediated transformation. The preliminary phytochemical analysis showed differences in the conten
Externí odkaz:
https://doaj.org/article/6b1f2e9aa94941d3a11d47344ea1cd0a
Autor:
Vera M. S. Isca, Joana Andrade, Ana Sofia Fernandes, Paulo Paixão, Clara Uriel, Ana María Gómez, Noélia Duarte, Patrícia Rijo
Publikováno v:
Molecules, Vol 25, Iss 18, p 4250 (2020)
The antimicrobial evaluation of twelve natural and hemisynthetic isopimarane diterpenes are reported. The compounds were evaluated against a panel of Gram-positive bacteria, including two methicillin-resistant Staphylococcus aureus (MRSA) strains and
Externí odkaz:
https://doaj.org/article/53e14e00c233453d82fd9269999d55ca
Autor:
Tomasz Śliwiński, Przemysław Sitarek, Ewa Skała, Vera M. S. Isca, Ewelina Synowiec, Tomasz Kowalczyk, Michał Bijak, Patrícia Rijo
Publikováno v:
Pharmaceuticals, Vol 13, Iss 6, p 123 (2020)
Plectranthus spp. is widely known for its medicinal properties and bioactive metabolites. The cytotoxic and genotoxic properties of the four known abietane diterpenoids: 7α-Acetoxy-6β-hydroxyroyleanone (Roy), 6,7-dehydroroyleanone (Deroy), 7β,6β-
Externí odkaz:
https://doaj.org/article/6f34151cd4e24fbe9a364778fea2ae7f