Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Vera M. Ripoll"'
Autor:
Ina Buchholz, Thomas McDonnell, Peter Nestler, Sudarat Tharad, Martin Kulke, Anna Radziszewska, Vera M. Ripoll, Frank Schmidt, Elke Hammer, Jose L. Toca-Herrera, Anisur Rahman, Mihaela Delcea
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Beta-2-glycoprotein I (β2GPI) is a blood protein and the major antigen in the autoimmune disorder antiphospholipid syndrome (APS). β2GPI exists mainly in closed or open conformations and comprises of 11 disulfides distributed across five d
Externí odkaz:
https://doaj.org/article/ab52dc10ebec4e0c9e466f4231064c67
Autor:
Akif A. Khawaja, Deborah L. W. Chong, Jagdeep Sahota, Theresia A. Mikolasch, Charis Pericleous, Vera M. Ripoll, Helen L. Booth, Saif Khan, Manuel Rodriguez-Justo, Ian P. Giles, Joanna C. Porter
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Neutrophilic inflammation correlates with mortality in fibrotic interstitial lung disease (ILD) particularly in the most severe form, idiopathic pulmonary fibrosis (IPF), although the underlying mechanisms remain unclear. Neutrophil function is modul
Externí odkaz:
https://doaj.org/article/5210d6d6f7624959a7d494252cd021f5
Autor:
Thomas C. R. McDonnell, Rohan Willis, Charis Pericleous, Vera M. Ripoll, Ian P. Giles, David. A. Isenberg, Allan R. Brasier, Emilio B. Gonzalez, Elizabeth Papalardo, Zurina Romay-Penabad, Mohammad Jamaluddin, Yiannis Ioannou, Anisur Rahman
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
APS is an autoimmune disease in which antiphospholipid antibodies (aPL) cause vascular thrombosis and pregnancy morbidity. In patients with APS, aPL exert pathogenic actions by binding serum beta-2-glycoprotein I (β2GPI) via its N-terminal domain I
Externí odkaz:
https://doaj.org/article/5dbe595d033240e5b72049f6a3eda9b1
Autor:
Thomas McDonnell, Bahar Artim-Esen, Chris Wincup, Vera M. Ripoll, David Isenberg, Ian P. Giles, Anisur Rahman, Charis Pericleous
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Antiphospholipid antibodies (aPL), the serological hallmark of antiphospholipid syndrome (APS), are a heterogeneous group of autoantibodies raised against circulating blood proteins. Of these proteins, the phospholipid-binding b2-glycoprotein I (β2G
Externí odkaz:
https://doaj.org/article/0ece953eefd0478c872233844c9d1904
Autor:
Nicola Farina, Ruya Abdulsalam, Thomas McDonnell, Charis Pericleous, Amrita D’Souza, Vera M Ripoll, Jemma Webster, David A Isenberg, Ian Giles, Anisur Rahman
Publikováno v:
Rheumatology.
Objective aPL are found in the blood of 20–30% of patients with SLE. Although aPL cause vascular thrombosis in the antiphospholipid syndrome, it is not clear whether positive aPL levels in early SLE increase risk of subsequent vascular events (VE).
Autor:
Thomas McDonnell, Vera M. Ripoll, Oliver Leach, Anisur Rahman, Amrita N. D’Souza, Charis Pericleous, David A. Isenberg, Ian Giles
Publikováno v:
Rheumatology (Oxford, England)
Objectives aPL are present in between 20 and 30% of patients with SLE. They can cause vascular events (VE) or pregnancy morbidity. aCL and anti-beta-2-glycoprotein I (anti-β2GPI) are measured in clinical practice. Domain I (DI) of β2GPI is the main
Autor:
Deborah L. W. Chong, J. Sahota, Saif Khan, Akif A. Khawaja, Vera M. Ripoll, Ian Giles, Manuel Rodriguez-Justo, Charis Pericleous, Helen Booth, Joanna C. Porter
Neutrophilic inflammation correlates with mortality in fibrotic interstitial lung disease (ILD) however, the underlying mechanisms remain unclear. We aimed to determine whether aberrant neutrophil activation is a feature of ILD and the relative role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d3c3c4862599dd1e51cfc09adc8017
https://doi.org/10.1101/2020.01.03.894196
https://doi.org/10.1101/2020.01.03.894196
Autor:
Vera M. Ripoll, Thomas McDonnell, Rachel C. Chambers, Natalia Smoktunowicz, Bahar Artim-Esen, Anisur Rahman, Charis Pericleous, David A. Isenberg, Ian J. Mackie, Eifion Robinson, Yiannis Ioannou, Ian Giles
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports
Scientific Reports
Factor (F) Xa reactive IgG isolated from patients with antiphospholipid syndrome (APS) display higher avidity binding to FXa with greater coagulant effects compared to systemic lupus erythematosus (SLE) non APS IgG. FXa signalling via activation of p
Publikováno v:
Rheumatology. 58
Autor:
Bahar Artim-Esen, Aylin Albay, Ian Giles, Charis Pericleous, Thomas McDonnell, Anisur Rahman, Vera M. Ripoll
Publikováno v:
Rheumatology. 58