Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Vera M. Poort"'
Autor:
Valentina Cordo’, Mariska T. Meijer, Rico Hagelaar, Richard R. de Goeij-de Haas, Vera M. Poort, Alex A. Henneman, Sander R. Piersma, Thang V. Pham, Koichi Oshima, Adolfo A. Ferrando, Guido J. R. Zaman, Connie R. Jimenez, Jules P. P. Meijerink
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
No targeted therapy has been approved yet for the treatment of T cell acute lymphoblastic leukemia. Here the authors show that unbiased phosphoproteomic profiling can identify targetable kinases and guide the design of personalized combination treatm
Externí odkaz:
https://doaj.org/article/c5d14de3e81a4a469e7a8481cdc98225
Autor:
Vera M Poort, Rico Hagelaar, Diego Montiel González, Jessica G.C.A.M. Buijs-Gladdines, Laurianne Trabut, Bram van Wijk, Jules PP Meijerink, Ruben Van Boxtel
Publikováno v:
Blood. 140:5909-5910
Publikováno v:
Blood Adv
T-cell lymphoblastic lymphoma (T-LBL) and lymphoblastic leukemia (T-ALL) represent malignancies that arise from the transformation of immature precursor T cells. Similarities in T-LBL and T-ALL have raised the question whether these entities represen
Autor:
Valentina, Cordo', Mariska T, Meijer, Rico, Hagelaar, Richard R, de Goeij-de Haas, Vera M, Poort, Alex A, Henneman, Sander R, Piersma, Thang V, Pham, Koichi, Oshima, Adolfo A, Ferrando, Guido J R, Zaman, Connie R, Jimenez, Jules P P, Meijerink
Publikováno v:
Nature communications. 13(1)
Protein kinase inhibitors are amongst the most successful cancer treatments, but targetable kinases activated by genomic abnormalities are rare in T cell acute lymphoblastic leukemia. Nevertheless, kinases can be activated in the absence of genetic d