Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Vera Lorenz"'
Autor:
Michika Mochizuki, Vera Lorenz, Robert Ivanek, Giacomo Della Verde, Emanuele Gaudiello, Anna Marsano, Otmar Pfister, Gabriela M. Kuster
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 10 (2017)
BackgroundRecent studies suggest that adult cardiac progenitor cells (CPCs) can produce new cardiac cells. Such cell formation requires an intricate coordination of progenitor cell proliferation and commitment, but the molecular cues responsible for
Externí odkaz:
https://doaj.org/article/eea1e1dc7a644ed18168efdfbb84e806
Autor:
Camilla Schinner, Lifen Xu, Henriette Franz, Aude Zimmermann, Marie-Therès Wanuske, Maitreyi Rathod, Pauline Hanns, Florian Geier, Pawel Pelczar, Yan Liang, Vera Lorenz, Chiara Stüdle, Piotr I. Maly, Silke Kauferstein, Britt M. Beckmann, Farah Sheikh, Gabriela M. Kuster, Volker Spindler
Publikováno v:
Circulation. 146(21)
Background: Arrhythmogenic cardiomyopathy (ACM) is characterized by progressive loss of cardiomyocytes with fibrofatty tissue replacement, systolic dysfunction, and life-threatening arrhythmias. A substantial proportion of ACM is caused by mutations
Autor:
Vera Lorenz, Camilla Schinner, Pawel Pelczar, C. Stuedle, H. Franz, B. M. Beckmann, M.-T. Wanuske, Volker Spindler, Lifen Xu, S. Kauferstein, P. I. Maly, Gabriela M. Kuster, A. Zimmermann, Florian Geier
BackgroundArrhythmogenic Cardiomyopathy (ACM) is characterized by progressive loss of cardiomyocytes with fibrofatty replacement, systolic dysfunction and life-threatening arrhythmias. A substantial proportion of ACM is caused by mutations in genes o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75533d51b7b8f3a1fdb8eba750ee2155
https://doi.org/10.1101/2021.09.02.458734
https://doi.org/10.1101/2021.09.02.458734
Autor:
Melania Balzarolo, Giacomo Della Verde, Otmar Pfister, Lydia Joray, Emma L. Robinson, Saskia C.A. de Jager, Hester M. den Ruijter, Gideon B Valstar, Stephane Heymans, Vera Lorenz, Michika Mochizuki, Beat A. Kaufmann, Gabriela M. Kuster, Lifen Xu
Publikováno v:
Cardiovascular Research, 118(14), 2973-2984. Oxford University Press
AIMS: Microvascular inflammation plays an important role in the pathogenesis of diastolic dysfunction (DD) and metabolic heart disease. NOX1 is expressed in vascular and immune cells and has been implicated in the vascular pathology of metabolic dise
Autor:
Volker Spindler, Lifen Xu, Camilla Schinner, Chiara Stüdle, Gabriela M. Kuster, Vera Lorenz, Henriette Franz
Publikováno v:
The FASEB Journal. 35
Autor:
Anna Marsano, Emanuele Gaudiello, Robert Ivanek, Otmar Pfister, Gabriela M. Kuster, Vera Lorenz, Giacomo Della Verde, Michika Mochizuki
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Recent studies suggest that adult cardiac progenitor cells ( CPC s) can produce new cardiac cells. Such cell formation requires an intricate coordination of progenitor cell proliferation and commitment, but the molecular cues responsible f
Autor:
Otmar Pfister, Vera Lorenz, Federica Facciotti, Berit I. Rosc-Schlüter, Stéphanie P. Häuselmann, Michika Mochizuki, Gabriela M. Kuster
Publikováno v:
Cardiovascular research
Aims: The highly expressed cell adhesion receptor CD29 (β1-integrin) is essential for cardiomyocyte growth and survival, and its loss of function causes severe heart disease. However, CD29-induced signalling in cardiomyocytes is ill defined and may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d895e3870c5e212a0df487d3fa5ef2
http://doc.rero.ch/record/300898/files/cvr348.pdf
http://doc.rero.ch/record/300898/files/cvr348.pdf
Autor:
Stéphanie P. Häuselmann, Gabriela M. Kuster, Berit I. Rosc-Schlüter, Otmar Pfister, Vera Lorenz
Publikováno v:
Antioxidants & redox signaling
The totality of functional cardiomyocytes and an intact cardiac progenitor cell pool are key players in the myocardial cell homeostasis. Perturbation of either one may compromise the structural and functional integrity of the heart and lead to heart
Autor:
Beat A. Kaufmann, Stéphanie P. Häuselmann, Gabriela M. Kuster, Otmar Pfister, Aleksandra Wodnar-Filipowicz, Christopher Mbah, Angelos Oikonomopoulos, Lifen Xu, Vera Lorenz, Ronglih Liao
Publikováno v:
Journal of the American College of Cardiology
Objectives The goal of this study was to define the role of FMS-like tyrosine kinase 3 (FLT3) in the heart. Background FLT3 is a prominent target of receptor tyrosine kinase inhibitors (TKIs) used for anticancer therapy. TKIs can cause cardiomyopathy
Autor:
Stéphanie P. Häuselmann, Gabriela M. Kuster, Berit I. Rosc-Schlüter, Otmar Pfister, Marijke Brink, Vera Lorenz, Isabelle Plaisance
Publikováno v:
Free radical biology & medicine
β(1)-Integrin mediates cardiomyocyte growth and survival and its proper regulation is essential for the structural and functional integrity of the heart. β(1)-Integrin expression is enhanced in hypertrophy, but the mechanism and significance of its